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Functionalized coatings by electrospinning for anti-oxidant food packaging
The development of advanced formulations used for food packaging applications, which behave as protection or preservation materials and improve consumers’ health offers a route to reduced food wastage. The present study deals with investigations on the possibility of obtaining functionalized coatings by electrospinning of poly(ɛ-caprolactone), a synthetic biodegradable polymer together with vitamin E (α-tocopherol), selected as plant-based phenolic antioxidant. In this approach electrospinning allows the production of high surface area materials and thus offering an increased antioxidant activity. The electrospun fibres of poly(ɛ-caprolactone)/vitamin E were obtained, studied and their antioxidant properties were evaluated by measuring the fibre reactivity with 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. The potential for extending the shelf-life of food products by using this approach is discussed
Chiral Lewis Acid Catalyzed Asymmetric Cycloadditions of Carbonyl Ylides Generated from Diazoimide Derivatives and Their Synthetic Applications to Indolizidine Alkaloids
Highly enantioselective 1,3-dipolar
cycloaddition reactions, catalyzed
by chiral Lewis acids, between several 3-(2-alkenoyl)-2-oxazolidinones
and carbonyl ylides that were generated from <i>N</i>-diazoacetyl
lactams are described. Reactions of <i>N</i>-diazoacetyl
lactams that possess 5-, 6-, and 7-membered rings were transformed
to the corresponding epoxy-bridged indolizidines, quinolizidines,
and 1-azabicyclo[5.4.0]Âundecanes with good to high enantioselectivities.
Regio- and stereoselective ring-opening of the epoxy-bridged indolizidine
cycloadduct gave the corresponding alcohol as a single diastereomer.
The sequence of asymmetric cycloaddition followed by ring-opening
was applied to the syntheses of several chiral indolizidine derivatives,
including (+)-tashiromine
Chiral Lewis Acid Catalyzed Asymmetric Cycloadditions of Carbonyl Ylides Generated from Diazoimide Derivatives and Their Synthetic Applications to Indolizidine Alkaloids
Highly enantioselective 1,3-dipolar
cycloaddition reactions, catalyzed
by chiral Lewis acids, between several 3-(2-alkenoyl)-2-oxazolidinones
and carbonyl ylides that were generated from <i>N</i>-diazoacetyl
lactams are described. Reactions of <i>N</i>-diazoacetyl
lactams that possess 5-, 6-, and 7-membered rings were transformed
to the corresponding epoxy-bridged indolizidines, quinolizidines,
and 1-azabicyclo[5.4.0]Âundecanes with good to high enantioselectivities.
Regio- and stereoselective ring-opening of the epoxy-bridged indolizidine
cycloadduct gave the corresponding alcohol as a single diastereomer.
The sequence of asymmetric cycloaddition followed by ring-opening
was applied to the syntheses of several chiral indolizidine derivatives,
including (+)-tashiromine