65 research outputs found

    The Concept of Welfare State in the Light of Islam and Modern World

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    The paper primarily deals with welfare state and the topic chosen for this discussion is of great importance in our everyday lives. The state is the territory where we live and enjoy our freedom as a whole. In this assignment It has been tried to discuss the real meaning of a State, the role of state in the life of an individual, the difference between Islamic welfare state and modern welfare State. State is considered as a mother of people due to duties and different aspects of a state, it can be influenced on the common manā€™s life. The early Islamic state set by the Prophet at Madina was the patronage of the people and modern state also claims as the custodian of People. This paper is a brief discussion, while it explores and highlights the role of state. &nbsp

    Earthquake Hazard in District Ziarat, Baluchistan: Mitigation Measures

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    The individual citizenā€™s preparedness for the impact and mitigation of potentially catastrophic future earthquakes in Ziarat district will depend on their level of understanding of seismic hazards in the region and the collateral damages. It is based on an adequate program of civil defence which includes the measures that must be taken for the protection of people. Present study aims at suggesting mitigation measures to suggest that the respondentsā€™ age, education and occupation are statistically significant with the vulnerability reduction, that is tested on Pearsonā€™s Chi-Square test. For this purpose, a sample of 193 households was surveyed from the four union councils of district Ziarat, with a semi-structured questionnaire using the proportional allocation method. It was found that earthquake hazard mitigation measures were significantly affected by peopleā€™s education level and occupation. A number of measures include the need of taking necessary measures in the study area for all age groups of population. Apart from launching essential education and training, awareness dissemination regarding highly hazardous and vulnerable areas/conditions of households at risk is indispensable

    DUODENAL TUMOR IN GASTROINTESTINAL STROMAL TUMORS: A RARE CASE

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    Gastrointestinal stromal tumors are commonly developed in gastrointestinal tract but in duodenum is less than 3% of all gastrointestinal neoplasm. The early diagnostic criteria are very difficult in these tumors in worldwide and being a challenge for medical team due to difficult anatomical structure of duodenum. The studyā€™s aim is to know the incident rate of duodenal gastrointestinal stromal tumors. The average age of these tumors is more than 40 years but in the current case, 19-years old female patient present with complaint of melena and anemia. Her family history was negative. She was diagnosed by scope test of oral gastric duodenum with biopsy, abdominal x-rays, computerized tomography scan and histopathology. The patient was treated by Classic Whippleā€™s procedure. According to the oncologist, patient has low risk of duodenal tumor from gastrointestinal stromal tumor. These tumors have no need to treat with adjuvant therapy: chemotherapy (Glavic) and radiation therapy after surgical resection

    Protein Engineering of Endoglucanase CelR of Clostridium thermocellum for Enhanced Expression

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    Background:Ā Enhanced production and improved properties of cellulases for a greater activity on plant biomass would rank amongst the top priorities for second-generation ethanol production. Based on the emergence of protein engineering as a cutting-edge technology for enhancing enzyme activity and expression level, the present study is aimed at the application of this technique to the major cellulosomal processing endoglucanase ofĀ C. thermocellum, CelR for refining enzyme characteristics.Ā Methods:Ā The full-length native enzyme gene (CelR) and a truncated version without the docking domains at C-terminus (CelR-CB) were PCR amplified using gene specific primers. The amplified PCR products were T/A cloned in the vector pTZ57 R/T and transformed inĀ E. coliĀ DH5Ī±. The cellulase genes from the confirmed transformed plasmids were sub-cloned in T7 promoter-based expression vector pET-28a and expression analysis was done inĀ E. coliĀ (DE3) BL21 codon Plus.Ā Results:Ā An SDS PAGE analysis of both the CelR derivatives revealed that the truncated version i.e. CelR-CB showed a two-fold increase in expression level as compared to the full-length enzyme.Ā Conclusion:Ā The increased expression level of CelR inĀ E. coliĀ coupled with its increased production therefore makes it a promising method for augmenting the recombinant enzyme production for potential applications.

    In-Reactor Polypropylene Functionalization-The Influence of Catalyst Structures and Reaction Conditions on the Catalytic Performance

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    To unravel the relationship between silylene-bridged metallocene catalyst structures and polymerization conditions and their effect on the performance in in-reactor functionalization of polypropylene, the behaviors of rac-Me2Si(2-Me-4-Ph-Ind)2ZrCl2/MMAO, rac-Me2Si(Ind)2ZrCl2, rac-Me2Si(2-Me-4-Ph-Ind)2HfCl2, and rac-Me2Si(Ind)2HfCl2 in propylene/aluminum alkyl-passivated 10-undecen-1-ol copolymerization were compared. Kinetic analysis revealed higher catalytic activities for zirconocenes compared to analogous hafnocenes. Both the zirconocene and hafnocene with substituted indenyl ligands afforded a higher molecular weight capability, improved stereo-selectivity, and enhanced ability to incorporate functionalized comonomers compared to their non-substituted congeners. An in-depth study of polypropylene functionalization using the best performing catalyst system, rac-Me2Si(2-Me-4-Ph-Ind)2ZrCl2/MMAO, at temperatures ranging from 40 to 100 Ā°C, revealed a linear inversely proportional correlation of polymerization temperature with functionalized comonomer reactivity (ā†‘Tp ā†’ ā†“ r1), copolymer molecular weight (ā†‘Tp ā†’ ā†“Mn), and melting temperature (ā†‘Tp ā†’ ā†“Tm). While performing well under standard laboratory polymerization conditions, rac-Me2Si(2-Me-4-Ph-Ind)2ZrCl2/MMAO showed limited molecular weight and stereo-selectivity capabilities under high-temperature (130-150 Ā°C) solution process conditions. Although immobilization of rac-Me2Si(2-Me-4-Ph-Ind)2ZrCl2 onto silica, allowing it to be used under industrially relevant slurry and gas-phase conditions, led to an active catalyst, it failed to incorporate any functionalized comonomer

    Characteristics and Assessment of Groundwater

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    Groundwater system is very vital to humanity and the ecosystem. Aquifers are determined based on the absence or presence of water table positioning, that is, confined, unconfined, leaky aquifers and fractured aquifers. The objective of this chapter is to discuss the characteristic and assessment of groundwater within the scope of vertical distribution of GW, types of the aquifer system, types of SW-GW interface, and SW-GW interaction at both local and regional scales. The properties of the aquifer depend on the physical characteristics of the materials (porosity, permeability, specific yield, specific storage, and hydraulic conductivities) which are determined by techniques like resistivity surveys and pumping tests followed by remote sensing and geographic information system for better information on the groundwater system. Furthermore, understanding the SW-GW interactions through available methods (seepage meter, heat tracer, and environmental tracer) is useful in watershed management, that is, risk management and assessment of the aquifer system

    Effect of Growth Stages and Lactic Acid Fermentation on Anti-Nutrients and Nutritional Attributes of Spinach (Spinacia oleracea)

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    Spinach (Spinacia oleracea) is a winter-season green, leafy vegetable grown all over the world, belonging to the family Amaranthus, sub-family Chenopodiaceae. Spinach is a low-caloric food and an enormous source of micronutrients, e.g., calcium, folates, zinc, retinol, iron, ascorbic acid and magnesium. Contrarily, it also contains a variety of anti-nutritional factors, e.g., alkaloids, phytates, saponins, oxalates, tannins and many other natural toxicants which may hinder nutrient-absorption. This study was aimed at investigating the effect of fermentation on improving the nutrient-delivering potential of spinach and mitigating its burden of antinutrients and toxicants at three growth stages: the 1st growth stage as baby leaves, the 2nd growth stage at the coarse stage, and the 3rd growth stage at maturation. The results revealed the significant (p < 0.05) effect of fermentation on increasing the protein and fiber content of spinach powder from 2.53 to 3.53% and 19.33 to 22.03%, respectively, and on reducing total carbohydrate content from 52.92 to 40.52%; the effect was consistent in all three growth stages. A significant decline in alkaloids (6.45 to 2.20 mg/100 g), oxalates (0.07 mg/100 g to 0.02 mg/100 g), phytates (1.97 to 0.43 mg/100 g) and glucosinolates (201 to 10.50 Āµmol/g) was observed as a result of fermentation using Lactiplantibacillus plantarum. Fermentation had no impact on total phenolic content and the antioxidant potential of spinach, as evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric-reducing antioxidant power (FRAP) assays. This study proposes fermentation as a safer bioprocess for improving the nutrient-delivering potential of spinach, and suggests processed powders made from spinach as a cost-effective complement to existing plant proteins
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