Zircaloy-4 and Incoloy 800H/HT Alloys for the Current and Future Nuclear Fuel Claddings

Fuel cladding is one of the most critical components of nuclear reactors; so it is important to improve our understanding of various properties and behaviors of the cladding under different conditions approximating the nuclear reactor environment. Moreover, the efficiency of energy production, in addition to safety concerns, has resulted in progressive improvement of nuclear reactors design from Generation I to Generation IV. To complement this progressive trend, materials used for fuel cladding need to be improved or new materials should be developed. In this thesis, I address problems in the improvement of present fuel cladding and also investigate fuel cladding materials to be used in future Generation IV nuclear reactors. In the case of current Zircaloy-4 fuel claddings, a detailed evaluation of the surface roughness effects on their performance and properties of Zircaloy-4 fuel claddings was studied. A smoother surface on Zircaloy-4 cladding tubes is demanded by the customers; however no systematic study is available addressing the effect of surface roughness on the claddings’ performance. Thus the effects of surface roughness on texture, oxidation, hydriding behaviors and mechanical properties of Zircaloy-4 cladding tubes were investigated using various methods. It was found that surface roughness has some effects on the oxidation of Zircaloy-4. Increasing the surface roughness would increase the weight gain, however, this effect was more pronounced at the initial oxidation stages. Synchrotron techniques were used to characterize the electronic structure of zirconium alloys in their oxidized and hydrided states. With this approach, complex interactions between hydrogen and oxygen in the zirconium matrix could be investigated, which could not be resolved using conventional methods. As a candidate for future fuel cladding material, Incoloy 800H/HT, which is expected to be considered in super-critical water-cooled Gen IV reactors, was studied in order to optimize microstructure, texture and grain boundary characteristics. A specific Thermo-Mechanical Processing (TMP) was employed to manipulate the texture, microstructure and grain boundary character distribution. The deformation and annealing textures of thermo-mechanically processed samples were investigated by means of X-ray diffraction and orientation imaging microscopy. It was found that different rolling paths lead to different textures. The origin of different textures in differently (unidirectional and cross) rolled Incoloy 800H/HT at high deformation strains were investigated. In addition, the recrystallization kinetic of differently rolled samples was studied. It was found that the oriented nucleation plays an important role in determining the recrystallization texture. Unidirectional rolled samples exhibited a faster recrystallization kinetic compared with cross rolled ones, due to the presence of γ-fibre. The effect of the aforementioned microstructural parameters (grain size, texture and GBCD) on the oxidation resistance of Incoloy 800H/HT in super-critical water was investigated. It was found that the oxidation resistance of Incoloy 800H/HT can be improved by TMP. The optimum TMP process for enhancing the oxidation resistance was proposed. Microstructural parameters that can improve the oxidation resistance of Incoloy 800H/HT were identified. These findings will contribute to the effective selection of fuel cladding material for application in Gen IV SCW reactors

Helicobacter pylori Outer Membrane Protein 18 ( Hp1125 ) Induces Dendritic Cell Maturation and Function

Background.  Dendritic cells (DCs) are potent antigen-presenting cells that initiate T-cell responses. A robust adaptive Th1 immune response is crucial to an adaptive (Th2) immune response necessary for vaccine-induced protective immunity against Helicobacter pylori. It has been shown that several outer membrane proteins (Omps) induce a robust antibody response. However, it is also known that the antibodies generated are not protective. Moreover there is great variation in the recognition of high molecular weight H. pylori proteins by sera from infected patients. In contrast to the high molecular weight proteins, serologic responses to small molecular weight proteins provide assessment of current infection with H. pylori and also of its eradication. Aim.  The goal of the study was to analyze the activation of the immune response by a specific low molecular weight Omp that is universally expressed by all H. pylori strains. Therefore, we studied interaction of H. pylori Omp18 with DCs. Methods.  Activation of murine bone marrow-derived DCs and production of cytokines by Omp18 was assessed by fluorescence-activated cell sorter (FACS) for costimulatory markers and ELISA, respectively. The ability of Omp18 stimulated DCs to induce lymphocyte proliferation was measured in a mixed leukocyte reaction. Results.  Omp18 induced higher expression of the B7 (CD80 and CD86) costimulatory molecule after 18 hours indicating processing and presentation of the antigen on the surface by bone marrow-derived DCs. The maturing DCs also secreted significant levels of IL-12, but was 4-fold less than that stimulated by whole bacteria. Omp18-primed DCs induced proliferation and release of IFNγ by syngeneic splenocytes. Conclusion.  We concluded that Omp18 is capable of activating DCs initiating a Th1 immune response.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73882/1/j.1523-5378.2005.00350.x.pd

Propiedades térmicas del mortero de cemento con diferentes proporciones de mezcla

The energy required for the heating and cooling of buildings is strongly dependant on the thermal properties of the construction material. Cement mortar is a common construction material that is widely used in buildings. The main aim of this study is to assess the thermal properties of cement mortar in terms of its ther­mal conductivity, heat capacity and thermal diffusivity in a wide range of grades (cement: sand ratio between 1:2 and 1:8). As there is insufficient information to predict the thermal conductivity and diffusivity of a cement mortar from its physical and mechanical properties, the relationships between thermal conductivity and diffu­sivity and density, compressive strength, water absorption and porosity are also discussed. Our results indicate that, for a cement mortar with a 28-day compressive strength in the range of 6–60 MPa, thermal conductivity, specific heat and thermal diffusivity are in the range of 1.5–2.7 W/(m.K), 0.87–1.04 kJ/kg.K and 0.89–1.26 (x10-6 m2/s), respectively. The scanning electron microscope (SEM) images showed that pore size varied from 18 μm to 946 μm for samples with different cement-to-sand ratios. The porosity of cement mortar has a signifi­cant effect on its thermal and physical properties. For this reason, thermal conductivity and thermal diffusivity was greater in cement mortar samples with a higher density and compressive strength.La energía reque­rida para la calefacción y la refrigeración de los edificios depende en gran medida de las propiedades térmicas del material de construcción. El mortero de cemento es un material de construcción común que se usa ampliamente en edificios. El objetivo principal de este estudio es evaluar las propiedades térmicas del mortero de cemento en términos de su conductividad térmica, capacidad térmica y difusividad térmica en una amplia gama de grados (relación cemento: arena entre 1: 2 y 1: 8). Como no hay información suficiente para predecir la conductividad térmica y la difusividad de un mortero de cemento a partir de sus propiedades físicas y mecánicas, también se discuten las relaciones entre la conductividad térmica y la difusividad y la densidad, la resistencia a la compresión, la absorción de agua y la porosidad. Los resultados indican que, para un mortero de cemento con una resistencia a la compresión de 28 días en el rango de 6–60 MPa, la conductividad térmica, el calor específico y la difusividad térmica están en el rango de 1.5–2.7 W / (mK), 0.87–1.04 kJ / kg·K y 0.89–1.26 (x10-6 m2/s), respectivamente. Las imágenes del microscopio electrónico de barrido (SEM) mostraron que el tamaño de poro variaba de 18 μm a 946 μm para muestras con diferentes proporciones de cemento:arena. La porosidad del mortero de cemento tiene un efecto significativo en sus propiedades térmicas y físicas. Por esta razón, la conductividad térmica y la difusividad térmica fueron mayores en las muestras de mortero de cemento con mayor densidad y resistencia a la compresión

MXene/rGO grafted sponge with an integrated hydrophobic structure towards light-driven phase change composites

While phase change materials (PCMs) have great potential for use in solar energy storage, they suffer from a lack of shape stability and energy conversion ability. In this study, proper amination of melamine sponge (MS) was designed to construct an integrated MXene and reduced graphene oxide (rGO) structure. The MXene/rGO layer is sufficiently robust to endure the capillary pressure caused by solvent evaporation during the airdrying process. In addition, the reduction of GO using oleylamine (OA) contributes to the protection of MXene from oxidation by preventing the surface of MXene nanosheets from being exposed to oxygen and moisture. The as-designed MXene/rGO sponges have been shown to effectively enhance the thermophysical and photo absorption properties of paraffin wax (PW) in the composite PCM. The composite with the highest amount of MXene/rGO maintained 93.3% of the latent heat of pure PW. The photothermal storage efficiency can reach as high as 93.0% at an MXene content of around 1%. A thermal conductivity enhancement of 66.9% can be achieved compared to the pure MS/PW composite. Therefore, this study presents a new approach for designing of high-performance phase change composites for waste-heat recovery and solar thermal energy storage applications.</p

Parametric study on the thermal performance enhancement of a thermosyphon heat pipe using covalent functionalized graphene nanofluids

Heat transfer characteristics of copper sintered heat pipe explored using a modified graphene nanoplatelets (GNP)-containing nanofluid with great dispersion stability as a novel working fluid. Firstly, a water dispersible GNP with specific desire was synthesized by the reaction of GNP sheets with the diazonium salt (DS) of sodium 4-aminoazobenzene-4-sulfonate. An X-ray photoelectron spectroscopy (XPS) test shown successful covalent functionalization of GNP using DS which provided special water dispersibility characteristics. The results indicate that the thermal conductivity enhancement was up to 17% by adding modified GNP sheets in the base fluid. It also, exhibited a maximum sedimentation of 16% after 840 hrs. Further research works were carried on thermal performance of heat pipe by varying nanofluid concentrations, filling ratio, input heating powers and inclination angles of heat pipes. The results proof that the maximum enhancements of the effective thermal conductivity and reduction in thermal resistance for purposed nanofluid atφ = 5% were 105% and 26.4%, respectively. Moreover, these good features of the GNP/DS nanofluid make it a very promising working fluid to enhance the thermal performance and efficiency of the current heat pipe systems

The frequency of human leukocyte antigen-DRB1 alleles, using sequence-based genotyping in 68 parents-child trios study in Iranian subjects

Background: The human leukocyte antigen-DRB1 (HLA-DRB1) locus is one of the most polymorphic human loci and has a crucial role in the immune system. Assessing the allelic frequencies of HLA-DRB1 locus would be a fundamental factor in defining the origin of populations, relationships with other populations, disease association studies and the constitution of unrelated bone marrow donor registries. In the current study HLA-DRB1 alleles and their frequencies are determined in a family-based study by DNA sequencing-based typing high-resolution (2 field) level of typing. Materials and Methods: Genomic DNA from 3 members of 68 unrelated families (a total of 204 individuals) was extracted. Exon 2 of DRB1 gene was amplified and performed useing AssignTM SBT v4.7 sequence analysis software.Results: We had DRB1*11:04 with frequency of 0.0931, DRB1*03:01 with 0.0882, DRB1*11:01 with 0.0735, DRB1*13:01 with 0.071 and also alleles DRB1*08:03, DRB1*13:42, DRB1*14:04 and DRB1*14:07 with frequency of 0.0024.Conclusion: A total of 34 different alleles were found in the study subjects with DRB1*11:04, DRB1*03:01, DRB1*11:01 being the most frequent alleles respectively.