56 research outputs found
Emojis Decoded: Leveraging ChatGPT for Enhanced Understanding in Social Media Communications
Emojis, which encapsulate semantics beyond mere words or phrases, have become
prevalent in social network communications. This has spurred increasing
scholarly interest in exploring their attributes and functionalities. However,
emoji-related research and application face two primary challenges. First,
researchers typically rely on crowd-sourcing to annotate emojis in order to
understand their sentiments, usage intentions, and semantic meanings. Second,
subjective interpretations by users can often lead to misunderstandings of
emojis and cause the communication barrier. Large Language Models (LLMs) have
achieved significant success in various annotation tasks, with ChatGPT
demonstrating expertise across multiple domains. In our study, we assess
ChatGPT's effectiveness in handling previously annotated and downstream tasks.
Our objective is to validate the hypothesis that ChatGPT can serve as a viable
alternative to human annotators in emoji research and that its ability to
explain emoji meanings can enhance clarity and transparency in online
communications. Our findings indicate that ChatGPT has extensive knowledge of
emojis. It is adept at elucidating the meaning of emojis across various
application scenarios and demonstrates the potential to replace human
annotators in a range of tasks.Comment: 12 pages, 2 page appendi
Pitfalls in Link Prediction with Graph Neural Networks: Understanding the Impact of Target-link Inclusion & Better Practices
While Graph Neural Networks (GNNs) are remarkably successful in a variety of
high-impact applications, we demonstrate that, in link prediction, the common
practices of including the edges being predicted in the graph at training
and/or test have outsized impact on the performance of low-degree nodes. We
theoretically and empirically investigate how these practices impact node-level
performance across different degrees. Specifically, we explore three issues
that arise: (I1) overfitting; (I2) distribution shift; and (I3) implicit test
leakage. The former two issues lead to poor generalizability to the test data,
while the latter leads to overestimation of the model's performance and
directly impacts the deployment of GNNs. To address these issues in a
systematic way, we introduce an effective and efficient GNN training framework,
SpotTarget, which leverages our insight on low-degree nodes: (1) at training
time, it excludes a (training) edge to be predicted if it is incident to at
least one low-degree node; and (2) at test time, it excludes all test edges to
be predicted (thus, mimicking real scenarios of using GNNs, where the test data
is not included in the graph). SpotTarget helps researchers and practitioners
adhere to best practices for learning from graph data, which are frequently
overlooked even by the most widely-used frameworks. Our experiments on various
real-world datasets show that SpotTarget makes GNNs up to 15x more accurate in
sparse graphs, and significantly improves their performance for low-degree
nodes in dense graphs.Comment: Extended Version of our WSDM'24 paper. 8 pages, 2 page appendi
Large Language Models and Causal Inference in Collaboration: A Comprehensive Survey
Causal inference has shown potential in enhancing the predictive accuracy,
fairness, robustness, and explainability of Natural Language Processing (NLP)
models by capturing causal relationships among variables. The emergence of
generative Large Language Models (LLMs) has significantly impacted various NLP
domains, particularly through their advanced reasoning capabilities. This
survey focuses on evaluating and improving LLMs from a causal view in the
following areas: understanding and improving the LLMs' reasoning capacity,
addressing fairness and safety issues in LLMs, complementing LLMs with
explanations, and handling multimodality. Meanwhile, LLMs' strong reasoning
capacities can in turn contribute to the field of causal inference by aiding
causal relationship discovery and causal effect estimations. This review
explores the interplay between causal inference frameworks and LLMs from both
perspectives, emphasizing their collective potential to further the development
of more advanced and equitable artificial intelligence systems
High-Resolution Boundary Detection for Medical Image Segmentation with Piece-Wise Two-Sample T-Test Augmented Loss
Deep learning methods have contributed substantially to the rapid advancement
of medical image segmentation, the quality of which relies on the suitable
design of loss functions. Popular loss functions, including the cross-entropy
and dice losses, often fall short of boundary detection, thereby limiting
high-resolution downstream applications such as automated diagnoses and
procedures. We developed a novel loss function that is tailored to reflect the
boundary information to enhance the boundary detection. As the contrast between
segmentation and background regions along the classification boundary naturally
induces heterogeneity over the pixels, we propose the piece-wise two-sample
t-test augmented (PTA) loss that is infused with the statistical test for such
heterogeneity. We demonstrate the improved boundary detection power of the PTA
loss compared to benchmark losses without a t-test component
Present and future of functionalized Cu current collectors for stabilizing lithium metal anodes
Li metal has been recognized as the most promising anode materials for next-generation high-energy-density batteries, however, the inherent issues of dendrite growth and huge volume fluctuations upon Li plating/stripping normally result in fast capacity fading and safety concerns. Functionalized Cu current collectors have so far exhibited significant regulatory effects on stabilizing Li metal anodes (LMAs), and hold a great practical potential owing to their easy fabrication, low-cost and good compatibility with the existing battery technology. In this review, a comprehensive overview of Cu-based current collectors, including planar modified Cu foil, 3D architectured Cu foil and nanostructured 3D Cu substrates, for Li metal batteries is provided. Particularly, the design principles and strategies of functionalized Cu current collectors associated with their functionalities in optimizing Li plating/stripping behaviors are discussed. Finally, the critical issues where there is incomplete understanding and the future research directions of Cu current collectors in practical LMAs are also prospected. This review may shed light on the critical understanding of current collector engineering for high-energy-density Li metal batteries
Effects of supplemental octanoate on hepatic lipid metabolism, serum biochemical indexes, antioxidant capacity and inflammation-related genes expression of large yellow croaker (Larimichthys crocea) fed with high soybean oil diet
Dietary high soybean oil (SO) levels might cause hepatic lipid deposition, induce oxidative stress and inflammatory response in aquatic animals, while octanoate (OCT) is beneficial to metabolism and health in mammals. However, the effect of OCT has been studied rarely in aquatic animals. In this study, a 10-week feeding trial was conducted to investigate the effect of supplemental OCT on hepatic lipid metabolism, serum biochemical indexes, antioxidant capacity and inflammatory response of large yellow croaker (Larimichthys crocea) fed with high SO levels diet. The negative control diet contained 7% fish oil (FO), while the positive control diet contained 7% SO. The other four experimental diets were supplemented with 0.7, 2.1, 6.3 and 18.9 g/kg sodium octanoate (OCT) based on the positive control diet. Results showed that OCT supplementation effectively reduced the hepatic crude lipid, triglyceride (TG), total cholesterol (TC) and non-esterified free fatty acids contents, and alleviated lipid accumulation caused by the SO diet. Meanwhile, OCT supplementation decreased the serum TG, TC, alanine transaminase, aspartate transaminase and low-density lipoprotein cholesterol levels, increased the serum high-density lipoprotein cholesterol level, improved the serum lipid profiles and alleviated hepatic injury. Furthermore, with the supplementation of OCT, the mRNA expression of genes related to lipogenesis (acc1, scd1, fas, srebp1, dgat1 and cebpα) and fatty acid (FA) transport (fabp3, fatp and cd36) were down-regulated, while the mRNA expression of genes related to lipolysis (atgl, hsl and lpl) and FA β-oxidation (cpt1 and mcad) were up-regulated. Besides that, dietary OCT increased the total antioxidant capacity, activities of peroxidase, catalase and superoxide dismutase and the content of reduced glutathione, decreased the content of 8-hydroxy-deoxyguanosine and malondialdehyde and relieved hepatic oxidative stress. Supplementation of 0.7 and 2.1 g/kg OCT down-regulated the mRNA expression of genes related to pro-inflammatory cytokines (tnfα, il1β and ifnγ), and suppressed hepatic inflammatory response. In conclusion, supplementation with 0.7-2.1 g/kg OCT could reduce hepatic lipid accumulation, relieve oxidative stress and regulate inflammatory response in large yellow croaker fed the diet with high SO levels, providing a new way to alleviate the hepatic fat deposition in aquatic animals
Knowledge and attitudes of healthcare workers in Chinese intensive care units regarding 2009 H1N1 influenza pandemic
<p>Abstract</p> <p>Background</p> <p>To describe the knowledge and attitudes of critical care clinicians during the 2009 H1N1 influenza pandemic.</p> <p>Methods</p> <p>A survey conducted in 21 intensive care units in 17 provinces in China.</p> <p>Results</p> <p>Out of 733 questionnaires distributed, 695 were completed. Three hundred and fifty-six respondents (51.2%) reported their experience of caring for H1N1 patients. Despite the fact that 88.5% of all respondents ultimately finished an H1N1 training program, only 41.9% admitted that they had the knowledge of 2009 H1N1 influenza. A total of 572 respondents (82.3%) expressed willingness to care for H1N1 patients. Independent variables associated with increasing likelihood to care for patients in the logistic regression analysis were physicians or nurses rather than other professionals (odds ratio 4.056 and 3.235, p = 0.002 and 0.007, respectively), knowledge training prior to patient care (odds ratio 1.531, p = 0.044), and the confidence to know how to protect themselves and their patients (odds ratio 2.109, p = 0.001).</p> <p>Conclusion</p> <p>Critical care clinicians reported poor knowledge of H1N1 influenza, even though most finished a relevant knowledge training program. Implementation of appropriate education program might improve compliance to infection control measures, and willingness to work in a pandemic.</p
Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial
Background: Previous cluster-randomized controlled trials evaluating the impact of implementing evidence-based guidelines for nutrition therapy in critical illness do not consistently demonstrate patient benefits. A large-scale, sufficiently powered study is therefore warranted to ascertain the effects of guideline implementation on patient-centered outcomes.
Methods: We conducted a multicenter, cluster-randomized, parallel-controlled trial in intensive care units (ICUs) across China. We developed an evidence-based feeding guideline. ICUs randomly allocated to the guideline group formed a local "intervention team", which actively implemented the guideline using standardized educational materials, a graphical feeding protocol, and live online education outreach meetings conducted by members of the study management committee. ICUs assigned to the control group remained unaware of the guideline content. All ICUs enrolled patients who were expected to stay in the ICU longer than seven days. The primary outcome was all-cause mortality within 28 days of enrollment.
Results: Forty-eight ICUs were randomized to the guideline group and 49 to the control group. From March 2018 to July 2019, the guideline ICUs enrolled 1399 patients, and the control ICUs enrolled 1373 patients. Implementation of the guideline resulted in significantly earlier EN initiation (1.20 vs. 1.55 mean days to initiation of EN; difference − 0.40 [95% CI − 0.71 to − 0.09]; P = 0.01) and delayed PN initiation (1.29 vs. 0.80 mean days to start of PN; difference 1.06 [95% CI 0.44 to 1.67]; P = 0.001). There was no significant difference in 28-day mortality (14.2% vs. 15.2%; difference − 1.6% [95% CI − 4.3% to 1.2%]; P = 0.42) between groups.
Conclusions: In this large-scale, multicenter trial, active implementation of an evidence-based feeding guideline reduced the time to commencement of EN and overall PN use but did not translate to a reduction in mortality from critical illness. Trial registration: ISRCTN, ISRCTN12233792. Registered November 20th, 2017
Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial.
BackgroundPrevious cluster-randomized controlled trials evaluating the impact of implementing evidence-based guidelines for nutrition therapy in critical illness do not consistently demonstrate patient benefits. A large-scale, sufficiently powered study is therefore warranted to ascertain the effects of guideline implementation on patient-centered outcomes.MethodsWe conducted a multicenter, cluster-randomized, parallel-controlled trial in intensive care units (ICUs) across China. We developed an evidence-based feeding guideline. ICUs randomly allocated to the guideline group formed a local "intervention team", which actively implemented the guideline using standardized educational materials, a graphical feeding protocol, and live online education outreach meetings conducted by members of the study management committee. ICUs assigned to the control group remained unaware of the guideline content. All ICUs enrolled patients who were expected to stay in the ICU longer than seven days. The primary outcome was all-cause mortality within 28 days of enrollment.ResultsForty-eight ICUs were randomized to the guideline group and 49 to the control group. From March 2018 to July 2019, the guideline ICUs enrolled 1399 patients, and the control ICUs enrolled 1373 patients. Implementation of the guideline resulted in significantly earlier EN initiation (1.20 vs. 1.55 mean days to initiation of EN; difference - 0.40 [95% CI - 0.71 to - 0.09]; P = 0.01) and delayed PN initiation (1.29 vs. 0.80 mean days to start of PN; difference 1.06 [95% CI 0.44 to 1.67]; P = 0.001). There was no significant difference in 28-day mortality (14.2% vs. 15.2%; difference - 1.6% [95% CI - 4.3% to 1.2%]; P = 0.42) between groups.ConclusionsIn this large-scale, multicenter trial, active implementation of an evidence-based feeding guideline reduced the time to commencement of EN and overall PN use but did not translate to a reduction in mortality from critical illness.Trial registrationISRCTN, ISRCTN12233792 . Registered November 20th, 2017
Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial (vol 26, 46, 2022)
BackgroundPrevious cluster-randomized controlled trials evaluating the impact of implementing evidence-based guidelines for nutrition therapy in critical illness do not consistently demonstrate patient benefits. A large-scale, sufficiently powered study is therefore warranted to ascertain the effects of guideline implementation on patient-centered outcomes.MethodsWe conducted a multicenter, cluster-randomized, parallel-controlled trial in intensive care units (ICUs) across China. We developed an evidence-based feeding guideline. ICUs randomly allocated to the guideline group formed a local "intervention team", which actively implemented the guideline using standardized educational materials, a graphical feeding protocol, and live online education outreach meetings conducted by members of the study management committee. ICUs assigned to the control group remained unaware of the guideline content. All ICUs enrolled patients who were expected to stay in the ICU longer than seven days. The primary outcome was all-cause mortality within 28 days of enrollment.ResultsForty-eight ICUs were randomized to the guideline group and 49 to the control group. From March 2018 to July 2019, the guideline ICUs enrolled 1399 patients, and the control ICUs enrolled 1373 patients. Implementation of the guideline resulted in significantly earlier EN initiation (1.20 vs. 1.55 mean days to initiation of EN; difference - 0.40 [95% CI - 0.71 to - 0.09]; P = 0.01) and delayed PN initiation (1.29 vs. 0.80 mean days to start of PN; difference 1.06 [95% CI 0.44 to 1.67]; P = 0.001). There was no significant difference in 28-day mortality (14.2% vs. 15.2%; difference - 1.6% [95% CI - 4.3% to 1.2%]; P = 0.42) between groups.ConclusionsIn this large-scale, multicenter trial, active implementation of an evidence-based feeding guideline reduced the time to commencement of EN and overall PN use but did not translate to a reduction in mortality from critical illness.Trial registrationISRCTN, ISRCTN12233792 . Registered November 20th, 2017
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