Leiomyoma in a female urethral diverticulum

Neoplasms arising within urethral diverticula are rare. It is important to know if a diverticulum is fi lled by tumor, but traditional diagnostic methods, such as voiding cystourethrography, cannot detect a tumor or diverticulum, as in our case. We report an unusual case of leiomyoma developing in a female urethra diverticulum and review the literature

THE RELATIONSHIP BETWEEN ATTACHMENT AND SERUM OXYTOCIN AND HEAT SHOCK PROTEIN-70 LEVELS IN ADOLESCENTS OF PARENTS WITH SCHIZOPHRENIA AND BIPOLAR DISORDER

Background: The aim of this study was to evaluate serum heat shock protein 70 (HSP70) and oxytocin levels, attachment and perceived social support levels in adolescents with parental bipolar disorder (BD) and Schizophrenia (SCZ). Subjects and Methods: This study included 9 adolescents with SCZ parents, 30 adolescents with BD parents and 31 healthy adolescents. Brief Symptom Inventory (BSI), Relationship Scale Questionnaire-Adolescent Form (RSQ-A) and Multidimensional Scale of Perceived Social Support (MSPSS) were administered to all participants. In addition, serum HSP-70 and oxytocin levels were evaluated. Results: There was no significant difference between the groups in terms of attachment style, psychiatric symptoms and perceived social support. Serum HSP-70 levels were found to be lower in adolescents whose parents had BD. Serum oxytocin levels of the SCZ group were significantly lower than those of the BD group. Conclusions: HSP-70 level was found to be lower in adolescents with BD parents. Oxytocin level was found to be lower in adolescents with SCZ parents. These findings suggest that HSP-70 and oxytocin may be a marker of early life stress in adolescents with parental psychopathology. However, studies are needed to evaluate the relationship between attachment, oxytocin and HSP-70 in adolescents exposed to parental psychopathology in early life

Evaluation of dexamethasone suppression test in fibromyalgia patients with or without depression

WOS: 000183769800004PubMed: 12811674Objective: While in most healthy persons dexamethasone administration suppresses cortisol synthesis from the adrenal cortex, such suppression is not usually observed in patients with depression. We set out to investigate whether the dexamethasone suppression test (DST) reveals any neurobiological relationship between fibromyalgia (FM) and depression related to the hypothalamic-pituitary-adrenal (HPA) axis. Method. To discover a relationship between depression and FM we performed the DST in 2 0 FM patients with depression, 26 FM patients without depression and 20 healthy subjects serving as a control group. Results: Compared with the control group the cortisol level was found to be significantly higher in response to the DST in FM patients with depression (p = 0.03; z: -2.165), but not in those without depression (p = 0.15 3 ; z: -1.429). The cortisol level was not found to be statistically significant when patients with FM without depression were compared with the control group (p = 0.249 z: -1.152). In 7 FM patients with depression the DST failed to suppress cortisol; this was statistically significant compared with FM patients without depression (p = 0.014) and the control group (p = 0.008). Among FM patients without depression cortisol was not suppressed in one case. Cortisol was suppressed in all the controls. There was no statistically significant difference in cortisol suppression between FM patients without depression and the control group (p = 1.00). Conclusion: Our findings show that the DST reveals no neurobiological relationship between FM and depression related to the HPA axis

The influence of sports on anxiety, depression, and perceived problem solving ability

Amaç: Bu çalışmada, düzenli egzersiz yapan sporcuların anksiyete, depresyon ve problem çözme becerisi algısı düzeyleri incelenerek bu değişkenlerin düzenli spor yapmayan bireylere göre farklı olup olmadığının saptanması amaçlanmıştır. Yöntem: Tüm katılımcılar 18-35 yaşları arasındaydı. Katılımcılar, düzenli olarak spor yapan (haftada en az 5 saat) 69 sporcu (35 takım sporcusu, 34 bireysel sporcu) ve düzenli olarak spor yapmayan 26 kontrol olmak üzere iki grupta değerlendirildi. Tüm katılımcılara Beck Depresyon Ölçeği (BDÖ), Beck Anksiyete Ölçeği (BAÖ), Problem Çözme Envanteri (PÇE) ve sosyodemografik verilerin değerlendirildiği bir anket uygulandı. Bulgular: Tüm sporcuların BAÖ skorları, kontrollere göre istatistiksel olarak anlamlı düzeyde düşük bulundu. Bireysel sporcular ve kontrollere göre, takım sporcularının BDE ve PÇE skorları istatistiksel olarak anlamlı düzeyde daha düşüktü. Tartışma: Bulgularımıza göre düzenli olarak spor yapmanın anksiyete üzerine olumlu etkisi bulunmaktadır. Düzenli olarak özellikle takım sporları yapmanın ise depresyon ve problem çözme becerisi üzerine olumlu etkisi olduğu söylenebilir.Objective: In this study we aimed to investigate the depression, anxiety, and perceived problem solving ability levels of sportmen who exercise regularly and to figure out if they differentiate from non-exercising population according to these variables. Methods: All participants were aged between 18 and 35. Two groups of participants were included as follows: 69 sportmen (35 team sportmen, 34 individual sportmen) who exercise regularly (at least 5 hours/week) and 26 controls who stated not to exercise regularly. All participants completed the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Problem Solving Inventory (PSI), and a sociodemographic form. Results: BAI scores of two sportmen groups were statistically lower than the controls’. The team sportmen in comparison with personal sportmen and controls had significantly lower scores in BDI and PSI. Discussion: Our findings reveal that sports participation in general has a positive effect on anxiety and team sports participation has a positive effect on depression and perceived problem solving ability in particular

A study on the effects of escitalopram treatment of mean platelet volume in patients with major depression [Major depresyonlu hastalarda ortalama trombosit hacmi: Essitalopram tedavisinin etkisi]

Introduction: The relationship between major depression and increased platelet activity has been previously indicated by several studies. The aim of this study was to examine mean platelet volume (MPV), which is an indicator of platelet activity, in depressed subjects and investigate whether escitalopram treatment would affect MPV. Methods: Fifteen patients (11 women and 4 men), meeting the criteria for a current episode of major depressive disorder were participated, as well as 17 physically and mentally healthy comparison subjects (11 women and 6 men). MPV and platelet count (PLC) of the controls and patients were measured at the entry to the study. After 8 weeks of open-label treatment with the selective serotonin reuptake inhibitor escitalopram (10-20 mg/d), the patients with depression were readmitted and the measurements were repeated. Results: In comparison with the control group, the depressed group exhibited greater platelet activity as detected by increased MPV. After escitalopram treatment, the patients with depression exhibited significant reduction in MPV. Conclusion: In this study, normalization of platelet activation is associated with escitalopram treatment of patients with depression. This finding may provide evidence for the use of escitalopram in patients with major depression and comorbid ischemic heart disease

The effect of escitalopram on platelet activity

WOS: 000285545500017PubMed: 20709365

A study on the effects of escitalopram treatment of mean platelet volume in patients with major depression

WOS: 000209020900079Introduction: The relationship between major depression and increased platelet activity has been previously indicated by several studies. The aim of this study was to examine mean platelet volume (MPV), which is an indicator-of platelet activity, in depressed subjects and investigate whether escitalopram treatment would-affect MPV. Methods: Fifteen patients (11 women and 4 men), meeting the criteria for a current episode of major depressive disorder were participated, as well as 17 physically and mentally healthy comparison subjects (11 women and 6 Men). MPV and platelet count (PLC) at the controls and patients were measured at the entry to the study. After 8 weeks of open-label treatment with the selective serotonin reuptake inhibitor escitalopram (10-20 mg/d), the patients with depression were readmitted and the measurements were repeated. Results: In Comparison with the control-group, the depressed group-exhibited greater platelet activity as detected by increased MPV. After escitalopram treatment, the patients with depression exhibited significant reduction in MPV. Conclusion: In this study, normalization of platelet activation is associated with escitalopram treatment of patients with depression. This finding may provide evidence for-the use of escitalopram in patients with major depression and comorbid ischemic heart disease

Mean Platelet Volume in Patients With Major Depression Effect of Escitalopram Treatment

WOS: 000267995200009PubMed: 19593177Background: The relationship between major depression and increased platelet activity has been previously indicated by several studies. The aims of this study were to examine mean platelet volume (MPV), which is an indicator of platelet activity, in patients with depression and investigate whether escitalopram treatment would affect MPV. Methods: Fifteen patients (11 women and 4 men) meeting the criteria for a current episode of major depressive disorder were recruited to the study and 17 physically and mentally healthy comparison subjects (11 women and 6 men). Mean platelet volume and platelet count of the controls and patients were measured upon entry to the study. After 8 weeks of open-label treatment with the selective serotonin reuptake inhibitor escitalopram (10-20 mg/d), the patients with depression were readmitted and the measurements were repeated. Results: At baseline, in comparison with the control group, the group with depression exhibited greater platelet activity as detected by increased MPV After escitalopram treatment, the patients with depression exhibited significant reduction in MPV There was also a significant decline in platelet count. Conclusions: In this study, normalization of platelet activation is associated with escitalopram treatment for patients with depression. This finding may provide evidence for the use of escitalopram in patients with major depression and comorbid ischemic heart disease

Memantine-Related Psychotic Symptoms in a Patient With Bipolar Disorder

WOS: 000280470700019PubMed: 20667296

Anksiyete, depresyon ve problem çözme becerisi algısı üzerine düzenli sporun etkisi

Objective: In this study we aimed to investigate the depression, anxiety, and perceived problem solving ability levels of sportmen who exercise regularly and to figure out if they differentiate from non-exercising population according to these variables. Methods: All participants were aged between 18 and 35. Two groups of participants were included as follows: 69 sportmen (35 team sportmen, 34 individual sportmen) who exercise regularly (at least 5 hours/week) and 26 controls who stated not to exercise regularly. All participants completed the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Problem Solving Inventory (PSI), and a sociodemographic form. Results: BAI scores of two sportmen groups were statistically lower than the controls'. The team sportmen in comparison with personal sportmen and controls had significantly lower scores in BDI and PSI. Discussion: Our findings reveal that sports participation in general has a positive effect on anxiety and team sports participation has a positive effect on depression and perceived problem solving ability in particular