Classical and Bayesian estimation for the extended odd Weibull power Lomax model with applications

A new continuous distribution called the extended odd Weibull power Lomax (ExOW-POLO) distribution is introduced and studied. Numerous reliability and statistical features are derived. Additionally studied are point estimates using maximum likelihood, maximum product space, least square, weighted least square, and Bayesian estimation techniques. The mean square error and bias of the maximum likelihood and Bayesian parameter estimators are computed using simulation approaches, such as Markov chain Monte Carlo. Two intraocular pressure (IOP) real datasets were conducted between January 2015 and February 2018 on 49 patients (84 eyes) under the age of two who presented with primary congenital glaucoma to the Paediatric Ophthalmology Unit of the Mansoura Ophthalmic Center of Mansoura University in Egypt have been fitted the ExOW-POLO distribution. Comparing the properties of the proposed distribution’s fitting of the data to recognized extensions of the Lomax distribution. The analysis revealed that the most well-known extensions of Lomax distribution were made by the ExOW-POLO distribution outfit. In addition, the correlation measures and independent sample test for the two IOP real datasets are introduced with (A) Levene’s test for equality of variances for the two cases and (B) the t-test for equality of means. For Levene’s test for equality of variances: the null hypothesis is that equal variances are assumed and the alternative hypothesis is that equal variances are not assumed

The Use of Ologen Implant in Childhood Glaucoma Surgeries: A Review

This study assesses the effectiveness and safety of using Ologen implants (Aeon Astron Europe BV, Leiden, The Netherlands) as an adjunctive therapy in childhood glaucoma surgeries. We systematically reviewed the existing literature across various electronic databases to examine the effectiveness and safety of Ologen implants in childhood glaucoma surgeries. Our analysis encompassed 14 studies on the use of Ologen implants in childhood glaucoma. Among these, seven were prospective, five were retrospective, and two did not specify their study design. Success rates varied depending on the type of surgery and the included childhood glaucoma subtype. The success rates for Ologen implants-augmented surgeries were as follows: 33.3-70% for trabeculectomy, 50-81% for combined trabeculotomy-trabeculectomy procedure, 33%-87% for glaucoma drainage device, and 60% in deep sclerectomy. Ologen implant has a potential role in mitigating postoperative fibrosis and enhancing success rates in various childhood glaucoma surgeries. However, the existing literature is limited. Future comparative prospective studies with larger cohorts are needed.</p