HAPS Gateway Link in the 5850-7075 MHz and Coexistence with Fixed Satellite Service

Gateway link is essential to connect HAPS platform to terrestrial based networks. This crucial link is incorporated in HAPS fixed service spectrum allocation in considerably high frequencies, renders the link for more attenuations by atmospheric gases, and rain effects, especially when the regional climate is not favorable. However, under the agenda item 1.20 of World Radio Conference-2012 (WRC-12) new HAPS allocation in the 5850-7075 MHz band is proposed. Although, spectrum features are incomparably reliable, on the contrary, Fixed Satellite Service (FSS) uplink transmissions will have signal levels much higher than those in HAPS systems and have the potential for causing interference at the HAPS gateway receiver. In this article a key aspect of co-channel interference phenomena is investigated to facilitate optimum frequency sharing in the band in question. By proposing mitigation techniques and statistical method this generic prediction model enhances the capability of the HAPS spectrum sharing and provides flexibility in spectrum planning for different fixed services

The charged lepton mass matrix and non-zero θ13\theta_{13} with TeV scale New Physics

We provide an explicit structure of the charged lepton mass matrix which is 2-3 symmetric except for a single breaking of this symmetry by the muon mass. We identify a flavor symmetric limit for the mass matrices where the first generation is decoupled from the other two in the charged lepton sector while in the neutrino sector the third generation is decoupled from the first two generations. The leptonic mixing in the symmetric limit can be, among other structures, the bi-maximal (BM) or the tri-bimaximal (TBM) mixing. Symmetry breaking effects are included both in the charged lepton and the neutrino sector to produce corrections to the leptonic mixing and explain the recent $\theta_{13}$ measurements. A model that extends the SM by three right handed neutrinos, an extra Higgs doublet, and two singlet scalars is introduced to generate the leptonic mixing.Comment: 28 pages, 24 figures. arXiv admin note: substantial text overlap with arXiv:1111.307

Some toxicological studies on house crickets in relation to their circadian rhythms

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SGLT-2 Inhibitors: A Novel Mechanism in Targeting Glycemic Control in Type 2 Diabetes Mellitus

OBJECTIVE: To review the chemistry, pharmacology, pharmacodynamics, pharmacokinetics, clinical efficacy, tolerability, dosing, drug interactions, and administration of canagliflozin, dapagliflozin, and empagliflozin, and comparing the benefit and risk aspects of using these agents in the older adult diabetes patient population. DATA SOURCES, STUDY SELECTION, DATA EXTRACTION, AND DATA SYNTHESIS: A search of PubMed using the terms SGLT-2 inhibitors, canagliflozin, dapagliflozin, empagliflozin, efficacy, and tolerability was performed to find relevant primary literature on each of the sodium/glucose cotransporter 2 (SGLT-2) inhibitors currently approved for use in type 2 diabetes. Phase III trials for all agents were included. All English-language articles from 2010 to 2015 appearing in these searches were reviewed for relevance to this paper. In addition, related articles suggested in the PubMed search were also reviewed. The SGLT-2 inhibitors have shown a reduction in hemoglobin A1c values and fasting plasma glucose levels with a low incidence of hypoglycemia. The incidence of mycotic infections is increased in patients taking an SGLT-2 inhibitor. CONCLUSION: SGLT-2 inhibitors may be a viable treatment option for patients not controlled on other oral agents. The risk of hypoglycemia is small. However, the clinical efficacy and tolerability of these agents has not been fully elucidated in older and frail patients

Fourth-generation SM imprints in B -> K^*l^+l^- decays with polarized K^*

The implication of the fourth-generation quarks in the B -> K^*l^+l^- (l=mu,tau) decays, when K^* meson is longitudinally or transversely polarized, is presented. In this context, the dependence of the branching ratio with polarized K^* and the helicity fractions (f_{L,T}) of K^* meson are studied. It is observed that the polarized branching ratios as well as helicity fractions are sensitive to the NP parameters, especially when the final state leptons are tauons. Hence the measurements of these observables at LHC can serve as a good tool to investigate the indirect searches of new physics beyond the Standard Model.Comment: 13 pages, 10 figures, V2: some of the graphs are modified according to the new data from recent experiments. arXiv admin note: substantial text overlap with arXiv:1107.569

Use of the painDETECT tool in rheumatoid arthritis suggests neuropathic and sensitization components in pain reporting.

Rheumatoid arthritis (RA) is an inflammatory autoimmune condition typified by systemic inflammation targeted toward synovial joints. Inhibition of proinflammatory networks by disease-modifying antirheumatic drugs, eg, methotrexate and biologic therapies, including tumor necrosis factor-α inhibitors, often leads to suppression of disease activity observed at the clinical level. However, despite the era of widespread use of disease-modifying treatments, there remain significant groups of patients who continue to experience pain. Our study formulated a pain assessment tool in the arthritis clinic to assess feasibility of measurements including the visual analog scale (VAS) and painDETECT to assess multimodal features of pain in people with established RA (n=100). Clinical measures of disease activity (Disease Activity Score in 28 Joints [DAS28]) were also recorded. Our data showed that despite the majority of subjects on at least one disease-modifying agent, the majority of patients reported severe pain (54%) by VAS, despite well-controlled clinical disease, with mean DAS28 2.07±0.9. Using the painDETECT questionnaire, 67% of patients had unlikely neuropathic pain. A significant proportion of subjects (28%) had possible neuropathic pain and 5% had features of likely neuropathic pain by painDETECT scoring. We found a positive correlation between VAS and painDETECT (R (2)=0.757). Of note, the group who had likely or probable neuropathic pain also showed significantly increased pain reporting by VAS (P30) also had statistically higher proportions of pain reporting (VAS 89.0±0.7 mm) compared with subjects who had a normal body mass index (VAS 45.2±21.8 mm), P<0.05. Our findings suggest that multimodal features of pain perception exist in RA, including neuropathic and sensitization elements, perhaps explaining why a subgroup of people with RA continue to experience ongoing pain, despite their apparent suppression of inflammation

Azimuthal Asymmetries in Hadronic Final States at HERA

The distribution of hadrons produced in deeply inelastic electron-proton collisions depends on the azimuthal angle between lepton scattering plane and hadron production plane in the photon-proton centre-of-mass frame. In addition to the well known up-down asymmetry induced by the azimuthal dependence of the Born level subprocess, there is also a non-vanishing left-right asymmetry, provided the incoming electron is polarized. This asymmetry is time-reversal-odd and induced by absorptive corrections to the Born level process. We investigate the numerical magnitude of azimuthal asymmetries in semi-inclusive hadron production at HERA with particular emphasis on a possible determination of the time-reversal-odd asymmetry.Comment: 9 pages, LaTeX, 7 figures included, The complete paper, including figures, is also available via anonymous ftp at ftp://ttpux2.physik.uni-karlsruhe.de/ttp99/ttp99-29/ or via www at http://www-ttp.physik.uni-karlsruhe.de/Preprints

Development of fisheries co-management in Cambodia : a case study and its implications

The livelihoods and food security of many Cambodians depend heavily on inland capture fisheries, so the sustainable management of these fisheries is very important. Notwithstanding, the sustainability of Mekong fisheries is threatened by increasing fishing pressure and habitat modifications. Current management is considered insufficiently capable of controlling levels of exploitation and achieving equitable distribution of the resource, and the Cambodian government is promoting co-management initiatives as a way of addressing these issues. Using an institutional analysis approach, the current performance of co-management in a Mekong mainstream fishery was assessed, and factors limiting success identified. Results suggest that performance and sustainability of co-management are currently constrained by a lack of clearly defined property rights and resource boundaries, a mismatch between resource scale and management initiatives, and an absence of enabling legislation. Furthermore, objectives for management differ between stakeholders and are not well defined overall. While enabling legislation due to come into effect shortly is expected to improve performance and sustainability of co-management, boundary and scale issues will continue to pose challenges to co-management in open systems such as the Mekong mainstream. As a result, calls for innovative solutions, such as a federation of co-management schemes, will continue. In addition, increasing dependence on fishing, and external threats to resources need to be addressed if sustainability is to be improvedFishery management, Inland fisheries, Cambodia,