Correlation Between Socio-Demographic Characteristics and Burden Among Family Caregivers of Psychotic Patients

A descriptive study using a convenience sample of family caregivers of psychotic patients recruiting from outpatient clinic and inpatients department in the Psychiatry and Neurology Hospital at Assiut University. They interviewed individually by using Socio-Demographic sheet and Burden Assessment Scale. More than forty percent of caregivers (41.9%) were in the age group, ranged from 45 to less than 60 years and 66.7 % of them were females. family caregivers had the highest mean score of time perspective burden (7.3±2.7) followed by financial problems (2.2±1.2) and personal distress (7.2±2.7). It can be concluded that, family caregivers of psychotic patients were highly suffering from burden related to time perspective and financial burden. Keywords: burden, family caregivers, and psychotic patients. DOI: 10.7176/JHMN/70-06 Publication date: January 31st 202

COVID-19 and the Unseen Benefits of Dexamethasone

According to World Health Organization (WHO) current updates, the COVID-19 pandemic has spread all over the globe affecting 216 countries and caused 8,860,331 confirmed cases and 465,740 deaths last followed by 24 June 2020. Many countries cannot afford the nucleic acid tests to confirm COVID-19 infected patients; as a result, people cannot know the COVID-19 status of the people living around them. The use of dexamethasone in COVID-19 hospitalized patients for up to 10 days lower 28-day mortality as compared to the patients taking usual care and also receiving mechanical ventilation at randomization (by age-adjusted percentage points 12.3, approximately one third of proportional reduction) and those patients receiving oxygen without invasive mechanical ventilation (by age-adjusted percentage points 4.1, approximately one fifth of proportional reduction)

CARACTÉRISATION DE LA FLORE DE LA FORÊT D’ACHEMECHE POUR UN AMÉNAGEMENT INTÉGRÉ ET UN DEVELOPPEMENT TERRITORIAL DURABLE DE LA COMMUNE RURALE DE RAS JERRY / PROVINCE D’EL HAJEB /MAROC

The forest of Achemeche is the indispensable support of the framework of life and of the natural resources of the rural commune of Ras jerry, it constitutes the back country of the territory which our major objective is to integrate it into the integrated management and sustainable territorial development of the commune. The diversity of its flora is located weakened more and more because of the significant pressures due to human and urban activities, a state of knowledge of its plants and its remarkable wildlife in a prime time will allow us to provide scenarios for their preservation, conservation and valorisation in a sustainable manner

Adult laryngeal haemangioma; a rare entity

Laryngeal haemangioma is commonly seen in children. Adult laryngeal haemangiomas are rare and usually involve the supraglottic region. Most common symptom includes dysphagia, dysphonia and shortness of breath. Detailed history, fiberoptic laryngoscopy and computerized scanning may suggest benign nature of the lesion but diagnosis is only confirmed by a biopsy. In comparison to infantile haemangiomas which usually respond to propronolol, the treatment of adult laryngeal haemangiomas is always surgical removal. We present a case report of a supraglottic haemangioma in an adult male, who was treated surgically without any complications

Role of Nε-(Carboxymethyl)Lysine in the Development of Ischemic Heart Disease in Type 2 Diabetes Mellitus

This study aims to determine the levels of Nε-(carboxymethyl)lysine (CML) in patients with Type 2 diabetic patients with and without ischemic heart disease (IHD) and to find for a possible association between circulating CML and a number of clinical parameters including lipids, hemoglobin A1c (HbA1c) and malondialdehyde (MDA) in Type 2 diabetic IHD patients. Serum CML levels were measured by enzyme-linked immunosorbent assay using polyclonal anti-CML antibodies. Serum levels of CML and MDA were assessed in 60 IHD patients with Type 2 diabetes, 43 IHD patients without Type 2 diabetes, 64 Type 2 diabetics without IHD, and 80 sex- and age-matched healthy subjects. Correlations studies between CML levels and lipids, HbA1c, and lipid peroxidation were performed in Type 2 diabetes patients with and without IHD. A statistical significance was observed in the levels of serum glucose, lipids (triglyceride, total cholesterol, HDL-cholesterol), MDA, HbA1c, CML and LDL-cholesterol (p<0.05) between the groups of the study. CML levels were significantly increased in diabetic IHD patients compared with Type 2 diabetes patients but without IHD (537.1 ± 86.1 vs 449.7 ± 54.9, p<0.001). A positive correlation was observed between serum levels of CML and MDA, r = 0.338 (p = 0.008) in Type 2 diabetes patients with IHD. However, age, HbA1c and lipids had no significant influence on CML levels among diabetics (p>0.05). In conclusion, this study demonstrates the effect of both diabetes and oxidative stress on the higher levels of circulating CML. These results showed that increased serum levels of CML are associated with the development of IHD in Type 2 diabetes mellitus

Nε-(Carboxymethyl)lysine and Coronary Atherosclerosis-Associated Low Density Lipoprotein Abnormalities in Type 2 Diabetes: Current Status

In comparison to the general population, individuals with diabetes suffer a 3- to 4-fold increased risk for developing complications of atherosclerosis and vascular insufficiency. This fact should be taken into account to develop a suitable determinant for the early detection of these complications and subsequently reduce the adverse effect of type 2 diabetes. In vitro experiments have shown that the products of glucose auto-oxidation and Amadori adducts are both potential sources of Nε-(carboxymethyl)lysine (CML). Excessive formation of CML on low density lipoprotein (LDL) has been proposed to be an important mechanism for the dyslipidemia and accelerated atherogenesis observed in patients with type 2 diabetes. It has been postulated that the uptake of CML-LDL by LDL receptors is impaired, thereby decreasing its clearance from the blood circulation. Alternatively, the uptake of these modified LDL particles by scavenger receptors on macrophages and vascular smooth muscle cells (SMCs) and by AGE receptors on endothelial cells, SMCs, and monocytes is highly enhanced and this, in turn, is centrally positioned to contribute to the pathogenesis of diabetic vascular complications especially coronary artery disease. The present review summarizes the up-to-date information on effects and mechanism of type 2 diabetes-associated coronary atherosclerosis induced by CML-LDL modification

HPC as a Service: A naive model

Applications like Big Data, Machine Learning, Deep Learning and even other Engineering and Scientific research requires a lot of computing power; making High-Performance Computing (HPC) an important field. But access to Supercomputers is out of range from the majority. Nowadays Supercomputers are actually clusters of computers usually made-up of commodity hardware. Such clusters are called Beowulf Clusters. The history of which goes back to 1994 when NASA built a Supercomputer by creating a cluster of commodity hardware. In recent times a lot of effort has been done in making HPC Clusters of even single board computers (SBCs). Although the creation of clusters of commodity hardware is possible but is a cumbersome task. Moreover, the maintenance of such systems is also difficult and requires special expertise and time. The concept of cloud is to provide on-demand resources that can be services, platform or even infrastructure and this is done by sharing a big resource pool. Cloud computing has resolved problems like maintenance of hardware and requirement of having expertise in networking etc. An effort is made of bringing concepts from cloud computing to HPC in order to get benefits of cloud. The main target is to create a system which can develop a capability of providing computing power as a service which to further be referred to as Supercomputer as a service. A prototype was made using Raspberry Pi (RPi) 3B and 3B+ Single Board Computers. The reason for using RPi boards was increasing popularity of ARM processors in the field of HPCComment: 2019 8th International Conference on Information and Communication Technologies (ICICT), Karachi, Pakistan, 201