Evaluation of oral health and bleeding management after dental procedures of patients with congenital bleeding disorders in Tehran city in 2015: A comparative study

Introduction: Platelets and clotting factors dysfunction lead to hereditary hemorrhagic disease. In according to the importance of these diseases, the aim of this study was the evaluation of oral health and bleeding management of the patients with congenital bleeding disorders in Tehran city in 2015. Methods: In this case-control study, 68 hemophilic patients  as case group were compared with 50 healthy people as control group. These samples matched in according to age and gender. DMFT/S and GI index (caries index and gingival index) was recorded and bleeding management evaluated by the patient's medical records and interviews. Data analyzed using SPSS version 16  and the level of significant was considered p ≤0.05. Results: Patients group The mean of age in hemophilic patients was 12.54 ± 2.94 and in the control group was 12.50±3.1. DMFT, DMFS and GI index was higher in the health group. With increasing the age of the patients  gingival inflammation index also increased significantly (p=0.001) so that 70% of individual with age higher than 15 had grade 3 gingival inflammation. Conclusions: Patients and parents awareness about dental hygiene and regular dental visit is very important for caries prevention and reduction of DMFT/S and GI index and regular dental visits are essential for the patients

Prevalence of Developmental Anomalies of Oral Mucosa within Patients Referred to Oral Medicine Department of Hamadan ِDentistry Faculty in 2014

Introduction: Developmental anomalies of oral mucosa are not necessarily related to a specific disease, that  may be demonstrated in differential diagnosis of oral disease and premalignant lesions. Mucosal anomalies incidence may be varied in different individuals, which can be related to many genetic and environmental elements. Therefore, this study aimed to evaluate the developmental anomalies of oral mucosa in the patients referred to department of Oral Medicine of Hamadan Dentistry faculty in 2014. Methods: In this cross-sectional study, the developmental anomalies of oral mucosa were studied in 800 patients, who referred to Hamadan School of Dentistry in Iran. All the 800 patients were clinically examined using dental mirrors on the dentistry unit in regard with diagnosis of mucosal anomalies. Demographic data and types of mucosal anomalies were recorded in a predesigned questionnaire. In order to analyze the study data, SPSS software (ver, 16) was applied via chi-square test at significance level of 0.05. Results: Oral developmental lesions were observed in 700 patients (87.5%). The most common lesion was reported as fissured tongue (50.9%), followed by Fordyce granules (49.5%), Macroglossia (17%), torousplatinus (13.4%). A significant association was detected between fissured tongue, macroglosia ,fordice granule with gender and age, Varicosities and furred tongue with age and Torus palatines , Comissural lip pit and hairy tongue with gender . Conclusion: The findings of the present study revealed high prevalence of oral mucosal anomalies. As a result, dentists and medical practitioners are demanded to attend to the oral mucosal anomalies

The validity, stability, and utility of measuring uric acid in saliva

AIM: Serum uric acid (UA) is associated with many health conditions, including kidney, cardiovascular, and metabolic disorders. We examined the validity and stability of salivary UA as a noninvasive measure of serum UA. MATERIALS & METHODS: Using serum and salivary UA data from healthy adults (n = 99), we examined the UA serum-saliva correlation, and UA associations with adiponectin and C-reactive protein. Using longitudinal data from young adults (n = 182), we examined salivary UA stability. RESULTS: We found robust positive serum-saliva correlations for UA. UA and adiponectin were inversely related in serum and saliva. Salivary UA was relatively stable; 62-66% of variance could be attributed to a latent trait-like component. CONCLUSION: Salivary UA may be an important biomarker indexing health and disease risk