Evaluation of the Correlation between Altmetric Attention Score and Citation Number of Top 50 Articles in Orthopedics

The altmetric Attention Score scale quantifies the attention that publications receive on various social media. Some studies have been conducted on the correlation between AAS and citations of articles in other disciplines but orthopedics. This study aimed to compare AAS with citation numbers on the top 50 articles regarding citation numbers. For this study the Scopus database was searched for the most 50 cited manuscripts on orthopedics from January 2015 to December 2020. Subsequently, altimetric attention score (AAS) and the number of Tweeters, Dimensions, etc, were retrieved for each article through "Bookmarklet for Researchers" at Altmetric.com. Results show a statistically low and non-significant relationship was indicated between the citation number and the AAS and also shown the linear relationship between the mention on Twitter and the altmetric attention score.  Most of previous articles represented that there is a weak to moderate relationship between the citation number and the AAS that is similar to our findings. There is a low but significant correlation exists between the AAS and the number of citations. In addition, the AAS is directly and linearly linked to the number of mentions on Twitter

Seasonal Pattern in Occurrence and In-hospital fatality rate from Traffic Accidents in Isfahan, Iran

Background:accident is the secondary cause of mortality in Iran, background of its occurrence and mortality are not wholly understood. The aim of this paper is to explain seasonal occurrence and mortality pattern of traffic accidents in Isfahan population, Iran Methods: This study is a cross-sectional analytic study. We extracted data on traffic accidents for Isfahan Province from the Ministry of Health (MOH). For analysis independent t test, ANOVA test, chi-square test was used. To calculate the odds ratio of death in hospital from traffic accidents, logistic regression model was used Results: The highest hospital admission for traffic accidents was seen during the summer and lowest during the autumn, they increased 43.35, 97.8 and 03.5 during the spring, summer and winter, respectively than the autumn. odds ratio for death from traffic accident during spring were (1.88 CI 95 0.98-1.42), summer (1.4 CI95 1.18-1.67) and in autumn (1.4 CI95 1.15-1.7),in male were (1.33 CI95 1.15-1.54) and in age group 21-40 were (1 CI95 0.87-1.16),41-60 (1.62 CI95 1.36-1.92),61≥(3.94 CI95 3.3-4.71) and in out of urban-rural (2.44 CI95 2.09-2.85),rural (3.1 CI95 2.64-3.64) and in motor vehicles(1.5 CI95 1.3-1.73)and in pedestrians(1.76 CI95 1.5-2.06) Conclusion: There are seasonal variations in occurrence and mortality due to traffic accidents. The highest occurrence of traffic accident was during summer, and the lowest rate in autumn. The highest in hospital mortality rate was observed in summer and the lowest in winter. After adjusting the model, the risk of in-hospital mortality was significant for gender,age,season, type of accidents and accident plac

Gender-Age Disparity of Cancers' Incidence in Iran

Cancer is one of the leading causes of death worldwide and among Iranian population; cancer is the third important causes of death. It is a critical issue to identify sex and age group difference of cancer pattern for planning and management of cancer patients, therefore the aim of present study was to examine sex and age difference in cancer incidence during 2003-2008 in Iran. The National Cancer Registry (NCR) reports from 2003 to 2008 have been applied to test trend of cancer incidence and illustrating sex-age disparity of most common cancers in Iran. Direct adjustment method was used for computing the age-specific rates (ASRs) and Cochran-Armitage tests for trends were used to test statistical significance of cancer incidence rate in both genders during 2003-2008. Our findings indicated that male and female incidence rate is increased from 64.2 to 117.5 and from 50.1 to 105.8, respectively during 2003-2008 (P for trend <0.001). Highest Age-Specific Rate of cancer in male was for stomach cancer (ASR=12.8), beside of skin cancer and in female was for breast cancer (ASR=33.2). Highest incidence rate of cancers was found in people aged 80-84 years in both genders. In elderly people, incidence rate of cancer was higher in male than female. The observed sex-age disparity of common cancers in this study indicated that male cancer of stomach and bladder and female cancer of breast and colorectal can be targeted in cancer control and prevention programs are required to reach remarkable reduction of cancer burden in Iran

Policy Brief for Reducing Contaminants and Residual Pesticides in Iran's Agricultural Crops

Background and Objective: The residual pesticides in agricultural crop have a negative impact on human health and lead to an increase in various diseases such as cancer. All aspects of the management process of pesticides control in the country requires intervention and quality improvement, according to Iran current situation of pesticide overuse and incorrect usage for various reasons, including lack of awareness among farmers, using cheap and low quality pesticides, existence of unauthorized pesticide shops. This study aimed to develop evidence-based programs to reduce and refine the usage of pesticides in the national level.Materials and Methods: To draft this policy document, we searched related upstream documents and studies and after assessing their validation with critical appraisal, used them to identify the problem. Then prioritized the factors affecting the problem, and extracted a conceptual model. Panel members also performed a focus group discussion on this model with content analysis method. Based on their scores of check lists, a primary draft of evidence-based policy options was prepared and after considering the feasibility and effectiveness of policy options, decisions were taken by Consensus on final version.Results: In this study six different intervention are introduced as policy options including: development of organic agriculture, increasing supervision on pesticides import to country, equipping the laboratories with private sector accompany, information provision to farmers, revising related legislations and coding the products.Conclusion: In case policy makers adhere all recommended policy options simultaneously, their effectiveness increases and pesticides problem will hopefully solve in the country.</p

Oncologic outcomes of Bacillus Calmette-Guérin therapy in elderly patients with non-muscle-invasive bladder cancer: A meta-analysis.

IntroductionThere is a challenge on the medical efficacy of intravesical Bacillus Calmette-Guérin (BCG) therapy and the power of the immune system boosting, which can be influenced by the age of the non-muscle-invasive bladder cancer (NMIBC) patients. This meta-analysis evaluates the efficacy of BCG therapy among aged (>70) and younger patients with non-muscle-invasive bladder cancer (NMIBC).MethodsThe central database of PubMed, Scopus, and Web of Science were queried until August 4, 2021, by using "BCG," "Bladder Cancer," "AGE," and "efficacy" keywords. After excluding duplicated results, titles and abstracts were evaluated by two independent reviewers. The exclusion criteria included non-English studies, conference abstracts, reviews, editorials, letters, and comments. Three main outcomes, disease-free survival (DFS), progression-free survival (PFS), and cancer-specific survival (CSS), were considered. The statistical analysis was performed using STATA (version 14; Stata Corp, College Station, Texas, USA).ResultsFrom 1115 found documents, the 24 research articles were recruited in the systematic review, and 10 were the candidate for meta-analysis. The overall estimate of H.R. revealed that BCG therapy in those over age 70 is significantly associated with an improved risk of progression and cancer-specific death in studied patients. However, this association was not statistically significant for DFS (1.04 (95% CI: 0.85,1.26)).ConclusionThe BCG maintenance therapy improved CSS and PFS oncological outcomes in elderly patients with NMIBC. BCG therapy did not significantly change the DSF

The Diagnostic Accuracy of Combined Enolase/Cr, CA125, and CA19-9 in the Detection of Endometriosis

Background. The present study was designed to verify the accuracy of the noninvasive biomarkers enolase/Cr, CA125, and CA19-9 as a clinical diagnostic tool for the detection of endometriosis. Methods. A cross-sectional study was performed at Rasool-e-Akram Hospital affiliated to Iran University of Medical Sciences, Tehran, Iran, from April 2015 to April 2018. Eighty-six women were scheduled to undergo laparoscopy due to chronic pelvic pain, infertility, pelvic mass, and abnormal uterine bleeding. Serum and urine samples of all patients were collected preoperatively. Serum levels of CA125 and CA19-9, and urine levels of enolase-1 were measured. Serum levels of CA125 and CA19-9 were determined by the electrochemiluminescence method (ECL). Urinary enolase-1 was measured by the ELISA method. Result. Serum levels of CA125 and CA19-9 were significantly higher in the endometriosis group than in controls (p<0.001, p=0.004, respectively). Levels of enolase I and enolase/Cr were higher in patients with endometriosis, but the differences were not statistically significant. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of combined enolase/Cr, CA125, and CA19-9 were 65%, 66.6%, 71%, and 60.1%, respectively. The positive likelihood ratio (PLR) and negative likelihood ratio (NLR) of combined enolase/Cr, CA125, and CA19-9 was 1.94 and 0.52, respectively. The area under the ROC curve for enolase/Cr+CA125+CA19−9 was 0.675 (95% confidence interval 0.573-0.710). Conclusion. The present study revealed that concurrent measurement of enolase-1, CA125, and CA19-9 might be a valuable noninvasive test for the identification of endometriosis

Determinants of delay in tuberculosis diagnosis in Hamadan province, 2006−2014

Introduction: Identifying factors that delay diagnosis of tuberculosis (TB) are important for the health system when timely patient treatment and reducing TB transmission are desirable goals. Aim of this study was to investigate the prognostic factors that delay TB diagnosis. Material and methods: This retrospective cohort study used National TB Program (NTP) data from 1056 TB patients during 2006–2014 in Hamadan province, western Iran. The Cox regression model was performed to determine associations between baseline explanatory variables and survival outcome with Hazard Ratio HRs (95% CIs). Results: N (%) of delay in TB diagnosis more than 90 days was significantly higher in male patients, new case patients and pulmonary positive cases. After adjustment for covariates, HR (95% CI) in relapsed TB compared to new cases was 0.67 (0.53, 0.85) and these figures for positive pulmonary cases and extra pulmonary cases in compared to negative pulmonary cases were 0.80 (0.68, 0.94) and 0.84 (0.73, 0.98) respectively. Conclusion: A high proportion of patients had delays in diagnosis exceeding three months. Our findings suggest that male gender, new cases, positive and extra pulmonary cases might increase the risk for delayeddiagnosis among TB patients

Pattern of Pediatric Animal Bites and Post Exposure Prophylaxis in Isfahan Province-Iran, 2015

Background: The incidence of animal bite is increasing in Iran and there is lack of knowledge about animal bite in children. Hence, the aim of this study was to describe the characteristics of animal bite in children and also evaluate delayed time of post exposure prophylaxis(PEP) in children. Materials and Methods: This cross-sectional study was conducted on 172 children cases of animal bites in Isfahan province in 2015. We used registered data from Rabies Treatment Center (RTC) of counties using the census method. Descriptive statistics were used to describe demographic and clinical status of bitten children. The Chi-square test was used to identify factors affecting on delayed time in PEP using Stata 12, software. Results: Of 172 cases, 66.8% were boy, and 68.0% lived in urban area. The cases were mainly bitten by cats (47.7%), and the most common sites of the animal bite were hands (55.8%). The bite incidents were happened more frequently in spring (32.0%). Overall, 30.8% of the cases received PEP by more than 48 hours after exposure. Conclusion: The results of this study showed that the pattern of animal bites is different in children compared with adults. More bites caused by cats, especially in the upper limbs. Delay in PEP in children is more common; therefore, it is necessary for parents to be sensitive in this regard