A convenient synthesis of 5-amino-4-(2-benzothiazolyl)pyrazoles

1175-117

A new convenient synthesis of 3-hetaryl-pyrazolo[5,1-c][1,2,4]triazines

Reactions of enaminones 2 with diazotized 5-amino-3-phenylpyrazole provide a convenient route to 3-[(4,5-disubstituted-pyrazol-3-yl)carbonyl]-pyrazolo[5,1-c][1,2,4]triazines. Condensation of the latter with hydrazine hydrate yielded the title compounds. The structures of the compounds prepared were elucidated on the basis of their spectral and elemental analyses

1,3,4-Thiadiazoles of pharmacological interest: Recent trends in their synthesis via tandem 1,3-dipolar cycloaddition: Review

This review article presents a survey of the utility of a new synthetic strategy for 1,3,4-thiadiazole derivatives based on reactions of nitrilimines with various functionalized sulfur dipolarophiles which proceed via tandem in situ 1,3-dipolar cycloaddition and β-elimination of simple molecule from the initially formed cycloadduct. The biological activities of some of the compounds prepared by such a strategy are pointed out. Only the literature reports within the period from 2000 to mid 2012 are covered

Synthesis and tautomerism of aryl- and hetaryl-azo derivatives of bi- and tri-heterocycles

This review summarizes results from the literature concerning synthesis and azo-hydrazone tautomerism of arylazo- and hetarylazo-derivatives of various bi- and tri-heterocycles reported by us and other research groups from 1981 to mid 2009