3 research outputs found

    Model reruang magnitud kecerahan langit di Balai Cerap KUSZA, Universiti Sultan Zainal Abidin (UNISZA)

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    Magnitud kecerahan langit merupakan antara aspek penting dalam bidang astronomi, terutama bagi cerapan astronomi optik yang memerlukan keadaan langit yang sangat gelap. Di Malaysia, terdapat banyak balai cerap rasmi dan persendirian yang digunakan bagi tujuan tersebut. Laporan kajian ini membincangkan berkenaan model taburan ruang (model reruang) bagi mendapatkan gambaran penuh magnitud kecerahan langit di sekitar Balai Cerap KUSZA (BCK) yang terletak di Kampung Merang, Setiu Terengganu. BCK dipilih dalam kajian ini kerana ia bukan sahaja merupakan lokasi rasmi bagi kerja-kerja pencerapan rukyah anak bulan baharu untuk penetapan takwim Islam (hilal), malah BCK juga menyediakan fasiliti bagi pengajaran dan pembelajaran (PdP) serta penyelidikan berkaitan astronomi dan astrofizik. Kajian ini penting bagi memastikan kelestarian cahaya gelap di BCK dan kawasan sekitarnya adalah releven dengan keperluan semasa. Magnitud kecerahan langit diukur pada waktu malam menggunakan alat pengesan cahaya (SQM) di beberapa lokasi sekitar BCK yang kemudiannya dibandingkan dengan data simulasi satelit. Seterusnya teknik interpolasi menggunakan Sistem Maklumat Geografi (GIS) dilakukan bagi menghasilkan peta model reruang kecerahan langit yang jelas menunjukkan kawasan langit gelap dan terang di BCK dan kawasan sekitarnya. Analisis data menunjukkan kewujudan beberapa lokasi langit cerah (penunjuk pencemaran cahaya) di sekitar kawasan BCK dengan nilai tertinggi adalah 16.35 mag arcsec−2 (3.115×10-2 cd m- ²) yang mungkin disebabkan oleh aktiviti manusia. Kecerahan langit di Balai Cerap KUSZA ialah 21.34 mag per arcsec−2 (3.144×10-4 cd m- ²) dan merupakan antara titik paling gelap dalam kawasan BCK. Secara keseluruhan, data menunjukkan kawasan sekitar balai cerap masih selamat daripada pencemaran cahaya yang keterlaluan. Walau bagaimanapun, pencemaran cahaya tidak terkawal akan mengganggu gugat aktiviti cerapan. Oleh itu, peta model reruang yang dihasilkan ini dijangka dapat membantu penyelidik astronomi optik untuk memantau kadar pencemaran cahaya di BCK bagi tujuan penyelidikan astronomi umumnya dan rukyah hilal secara khususnya di Malaysia

    Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries

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    © 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit

    Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

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    © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research
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