Elaboration of sponge-like biodegradable cationic particles via double-emulsion solvent evaporation

International audienc

Triazole containing magnetic core-silica shell nanoparticles for Pb 2+ , Cu 2+ and Zn 2+ removal

International audienc

Electrokinetic properties of bare and particles containing textile

International audienc

Submicron polycaprolactone particles as a carrier for imaging contrast agent for in vitro applications

International audienc

Combination of PCR and dual nanoparticles for detection of Plasmodium falciparum

We thank Dr. Chanin Nantasenamat for linguistic advice. We also thank Miss Siriruk Changrob and Miss Jitrada Wongpreecha for graphical artworks.International audienceHighly reactive particle-based DNA amplification was developed for the detection of the Pfg377 gene from P. falciparum gametocytes using functional magnetic latex particles (MLPs) and quantum dots encapsulated polymer particles (QDs-PPs). Firstly, MLPs were prepared from the precipitation of iron oxide, polymerization using initiator, and adsorption of aminodextran (AMD) so as to provide amino-functionalized MLPs. Furthermore, amino-containing polymer particles (PPs) were prepared by emulsifier-free polymerization and encapsulated with fluorescent quantum dots (QDs) for use as a signaling support. Subsequently, poly(maleic anhydride-alt-methyl vinyl ether) (PMAMVE) copolymer was effectively used for rapid and simple grafting of amino-modified DNA primers onto the surface of amino-functionalized particles thereby providing a promising method for particle immobilization. Herein, primer-grafted particles were applied in the amplification of the Pfg377 gene using the PCR approach. After amplification, PCR products containing PMAMVE-grafted MLPs and QDs-PPs were separated using a magnet and examined via a fluorescence microscope. PMAMVE-grafted particles were not found to inhibit the PCR reaction while facilitating efficient fluorescent detection of the PCR product. Results showed high sensitivity and specificity for the detection of amplified Pfg377 gene within only a few steps. This procedure represents a novel improvement to the post-amplification analysis

Sponge like microparticles for drug delivery and cosmeto-textile use: Formulation and human skin penetration

International audienc

Protein-Based Nanoparticle Preparation via Nanoprecipitation Method

International audienc

Polycaprolactone Based Nanoparticles Loaded with Indomethacin for Anti-Inflammatory Therapy: From Preparation to Ex Vivo Study

International audienc

Biphasic (Janus), Core–Shell and Functionalized Magnetic Polymer Particles: A Route of Synthesis to Application

International audienc