Supervivencia en pacientes con COVID-19 ingresados en UCI en un hospital de tercer nivel de Lambayeque, Perú.

Introduction: COVID-19, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has reached pandemic proportions worldwide, persisting over time. In this context, this study aims to analyze the factors associated with mortality in hospitalized patients with COVID-19 in a third-level hospital in the Lambayeque region. Material and metodo: A retrospective cohort study was conducted on patients diagnosed with COVID-19, hospitalized at the National Hospital Almanzor Aguinaga Asenjo (HNAAA) during the months of March to September 2020. Results: Forty patients admitted to the Intensive Care Unit (ICU) were examined, of whom twenty-two required mechanical ventilation (MV). Overall mortality in the ICU was 68.7%, while mortality among patients who required mechanical ventilation was 91.6%. A statistical association was found between death and vital signs on admission to the ICU, as well as with the waiting time for admission. The probability of survival at 2 and 7 days was 90.1% and 45.5%, respectively. Conclusions: In this cohort, a mortality rate of 68.7% was observed in the ICU, with a survival rate of 45.5% at 7 days and less than 10% at 18 days. No associations were found between survival and any of the variables of interest.Introducción: La COVID-19, causada por el Coronavirus 2 del Síndrome Respiratorio Agudo Severo (SARS-CoV-2), ha alcanzado proporciones pandémicas a nivel mundial, prolongándose en el tiempo. En este contexto, el presente estudio tiene como objetivo analizar los factores asociados a la mortalidad en pacientes hospitalizados por COVID-19 en un hospital de tercer nivel de la región Lambayeque. Material y método: Se realizó un estudio de cohorte retrospectivo de los pacientes con diagnóstico de COVID-19, hospitalizados en el Hospital Nacional Almanzor Aguinaga Asenjo (HNAAA) durante los meses de marzo a septiembre del 2020.  Resultados: Se examinaron cuarenta pacientes que ingresaron en la Unidad de Cuidados Intensivos (UCI), de los cuales veintidós necesitaron ventilación mecánica (VM). La mortalidad general en la UCI fue del 68.7%, mientras que la mortalidad entre los pacientes que necesitaron ventilación mecánica fue del 91.6%. Se encontró una asociación estadística entre el fallecimiento y los signos vitales al ingreso en la UCI, así como con el tiempo de espera para el ingreso. La probabilidad de supervivencia a 2 y 7 días fue del 90.1% y del 45.5%, respectivamente. Conclusiones: En esta cohorte, se observó una tasa de mortalidad del 68.7% en UCI, con una tasa de supervivencia del 45.5% a los 7 días y menos del 10% a los 18 días. No se encontró asociaciones entre la supervivencia y ninguna de las variables de interés

Factors associated with mortality in patients hospitalized for COVID-19 admitted to a tertiary hospital in Lambayeque, Peru, during the first wave of the pandemic.

IntroductionCOVID-19 caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spread worldwide, becoming a long-term pandemic.ObjectivesTo analyze the factors associated with mortality in patients hospitalized for COVID-19 in a tertiary hospital in the Lambayeque region of Peru.MethodsA retrospective cohort study of patients with a diagnosis of COVID-19, hospitalized in a hospital in northern Peru, was conducted from March to September 2020.ResultsOf the 297 patients studied, 69% were women, the mean age was 63.99 years (SD = ±15.33 years). Hypertension was the most frequent comorbidity (36.67%), followed by diabetes mellitus (24.67%) and obesity (8.33%). The probability of survival at 3 days of ICU stay was 65.3%, at 7 days 24.2%, and 0% on day 14. Risk factors associated with mortality in patients hospitalized for COVID-19 are age, male sex, tachypnea, low systolic blood pressure, low peripheral oxygen saturation, impaired renal function, elevated IL-6 and elevated D-dimer.ConclusionsMortality in hospitalized patients with COVID-19 was 51.18 per 100 persons, Mortality was found to be associated with hypertension, type of infiltrating, and sepsis

Prevalence of computer vision syndrome during the COVID-19 pandemic: a systematic review and meta-analysis

Abstract Background Computer vision syndrome has become a significant public health problem, especially in developing countries. Therefore, this study aims to identify the prevalence of computer vision syndrome during the COVID-19 pandemic. Methods A systematic review and meta-analysis of the literature was conducted using the databases PubMed, Scopus, Web of Science, and Embase up to February 22, 2023, using the search terms "Computer Vision Syndrome" and "COVID-19". Three authors independently performed study selection, quality assessment, and data extraction, and the Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument was used to evaluate study quality. Heterogeneity was assessed using the statistical test I 2 , and the R version 4.2.3 program was used for statistical analysis. Results A total of 192 studies were retrieved, of which 18 were included in the final meta-analysis. The total sample included 10,337 participants from 12 countries. The combined prevalence of computer vision syndrome was 74% (95% CI: 66, 81). Subgroup analysis based on country revealed a higher prevalence of computer vision syndrome in Pakistan (99%, 95% CI: 97, 100) and a lower prevalence in Turkey (48%, 95% CI: 44, 52). In addition, subgroup analysis based on study subjects showed a prevalence of 82% (95% CI: 74, 89) for computer vision syndrome in non-students and 70% (95% CI: 60, 80) among students. Conclusion According to the study, 74% of the participants experienced computer vision syndrome during the COVID-19 pandemic. Given this finding, it is essential to implement preventive and therapeutic measures to reduce the risk of developing computer vision syndrome and improve the quality of life of those affected. Trial registration The protocol for this systematic review and meta-analysis was registered in the international registry of systematic reviews, the International Prospective Register of Systematic Reviews (PROSPERO), with registration number CRD42022345965

Quality of Life, Anxiety, and Depression in Peruvian Patients with Acute Coronary Syndrome

The current study aims to identify the factors associated with anxiety and depression in patients with acute coronary syndrome (ACS) at hospital discharge from a Peruvian health center. Patients at discharge from the cardiology hospitalization service between November 2019 and December 2020 were evaluated using a cross-sectional study. The median time elapsed from the ACS event to the interview date was 10 months. A total of 34.1% of the population presented mild depression and 78.8% had mild anxiety. All three of our analyses indicated that patients who had attended university had significantly lower levels of both depression and anxiety, and patients with diabetes had significantly higher levels of anxiety. The lower-low socioeconomic group had 1.5 times the frequency of depression (p-value = 0.002) and 3.12 times the frequency of anxiety (p-value = 0.050). Interestingly, while a good quality of life was associated with lower levels of depression, it was also associated with higher levels of moderate/severe anxiety (p-value = 0.035). A multiple regression analysis found that hypertension was also associated with higher levels of anxiety, and patients who have had COVID-19 had 21.05 times the level of moderate/severe anxiety (p-value = 0.000). Cases of ACS are more frequent in patients with an age greater than or equal to 60 years, as well as in males. Isolation was a common feature that may have a negative impact on their quality of life and mental health

Calidad de vida, ansiedad y depresión en pacientes peruanos con síndrome coronario agudo

El presente estudio tiene como objetivo identificar los factores asociados a la ansiedad y depresión en pacientes con síndrome coronario agudo (SCA) al alta hospitalaria de un centro de salud peruano. Los pacientes al alta del servicio de hospitalización de cardiología entre noviembre de 2019 y diciembre de 2020 fueron evaluados mediante un estudio transversal. La mediana de tiempo transcurrido desde el evento de SCA hasta la fecha de la entrevista fue de 10 meses. El 34,1% de la población presentó depresión leve y el 78,8% ansiedad leve. Nuestros tres análisis indicaron que los pacientes que habían asistido a la universidad tenían niveles significativamente más bajos tanto de depresión como de ansiedad, y los pacientes con diabetes tenían niveles significativamente más altos de ansiedad. El grupo socioeconómico bajo-bajo tuvo 1,5 veces más frecuencia de depresión ( p-valor = 0,002) y 3,12 veces la frecuencia de la ansiedad ( p -valor = 0,050). Curiosamente, mientras que una buena calidad de vida se asoció con niveles más bajos de depresión, también se asoció con niveles más altos de ansiedad moderada/grave ( valor de p = 0,035). Un análisis de regresión múltiple encontró que la hipertensión también se asoció con niveles más altos de ansiedad, y los pacientes que habían tenido COVID-19 tenían 21,05 veces el nivel de ansiedad moderada/grave ( valor de p = 0,000). Los casos de SCA son más frecuentes en pacientes con una edad mayor o igual a 60 años, así como en el sexo masculino. El aislamiento fue una característica común que puede tener un impacto negativo en su calidad de vida y salud mental