Assessing the Hierarchical Hamiltonian Splitting Integrator for Collisionless N-body Simulations

The N-body problem has become one of the hottest topics in the fields of computational dynamics and cosmology. The large dynamical range in some astrophysical problems led to the use of adaptive time steps to integrate particle trajectories, however, the search of optimal strategies is still challenging. We quantify the performance of the hierarchical time step integrator Hamiltonian Splitting (HamSp) for collisionless multistep simulations. We compare with the constant step Leap-Frog (LeapF) integrator and the adaptive one (AKDK). Additionally, we explore the impact of different time step assigning functions. There is a computational overhead in HamSp however there are two interesting advantages: choosing a convenient time-step function may compensate and even turn around the efficiency compared with AKDK. We test both reversibility and time symmetry. The symmetrized nature of the HamSp integration is able to provide time-reversible integration for medium time scales and overall deliver better energy conservation for long integration times, and the linear and angular momentum are preserved at machine precision. We address the impact of using different integrators in astrophysical systems. We found that in most situations both AKDK and HamSp are able to correctly simulate the problems. We conclude that HamSp is an attractive and competitive alternative to AKDK, with, in some cases, faster and with better energy and momentum conservation. The use of recently discussed Bridge splitting techniques with HamSp may allow to reach considerably high efficiency.Comment: 13 pages, 16 figure

International nosocomial infection control consortium (INICC) report, data summary of 36 countries, for 2004-2009

The results of a surveillance study conducted by the International Nosocomial Infection Control Consortium (INICC) from January 2004 through December 2009 in 422 intensive care units (ICUs) of 36 countries in Latin America, Asia, Africa, and Europe are reported. During the 6-year study period, using Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN; formerly the National Nosocomial Infection Surveillance system [NNIS]) definitions for device-associated health care-associated infections, we gathered prospective data from 313,008 patients hospitalized in the consortium's ICUs for an aggregate of 2,194,897 ICU bed-days. Despite the fact that the use of devices in the developing countries' ICUs was remarkably similar to that reported in US ICUs in the CDC's NHSN, rates of device-associated nosocomial infection were significantly higher in the ICUs of the INICC hospitals; the pooled rate of central line-associated bloodstream infection in the INICC ICUs of 6.8 per 1,000 central line-days was more than 3-fold higher than the 2.0 per 1,000 central line-days reported in comparable US ICUs. The overall rate of ventilator-associated pneumonia also was far higher (15.8 vs 3.3 per 1,000 ventilator-days), as was the rate of catheter-associated urinary tract infection (6.3 vs. 3.3 per 1,000 catheter-days). Notably, the frequencies of resistance of Pseudomonas aeruginosa isolates to imipenem (47.2% vs 23.0%), Klebsiella pneumoniae isolates to ceftazidime (76.3% vs 27.1%), Escherichia coli isolates to ceftazidime (66.7% vs 8.1%), Staphylococcus aureus isolates to methicillin (84.4% vs 56.8%), were also higher in the consortium's ICUs, and the crude unadjusted excess mortalities of device-related infections ranged from 7.3% (for catheter-associated urinary tract infection) to 15.2% (for ventilator-associated pneumonia). Copyright © 2012 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved

Volvimos a las aulas... ¿y cómo? : experiencias y propuestas de enseñanza 2020-2021

Mohaded, Ana María. Universidad Nacional de Córdoba. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina.Domínguez Pesce, Agustín. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Música; Argentina.Salit, Celia. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Música; Argentina.Estarellas, Natalia. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Menoyo, Sofía G. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Argüello, Cecilia Beatriz. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Música; Argentina.Sajeva, Maura Jorgelina. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Teatro; Argentina.Irazusta, María Cecilia. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Otero Gruer, Dolores. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Mendizabal, Lilian Isabel. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Teatro; Argentina.Cáceres, Carlos Esteban. Universidad Nacional de Córdoba. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina.Fernández, Juan Manuel. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina.Menta, María Eugenia. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Música; Argentina.Hernández, Alejandra Fabiana. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Miranda, Adriana Esther. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Vivanco, Fernanda. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Teatro; Argentina.Serra, Mariela. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Teatro; Argentina.Altamirano, Ivana Verónica. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Teatro; Argentina.Bravo, Carolina. Universidad Nacional de Córdoba. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina.Jacobo, Mónica. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Sequeira, Jazmín. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Teatro; Argentina.Suárez, Victoria Inés. Universidad Nacional de Córdoba. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina.Yaya Aguilar, María Marcela. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Cine y Televisión; Argentina.Curletto, Hugo Daniel. Universidad Nacional de Córdoba. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina.Checchi, Pablo Martín. Universidad Nacional de Córdoba. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina.Nuestra principal responsabilidad como institución educativa universitaria es la formación de ciudadanes, garantizando saberes con los que puedan construir y sostener proyectos de vida en marcos de libertad compartida y promoviendo pers- pectivas que aporten en la transformación de la sociedad con parámetros más jus- tos, inclusivos y fraternos. Esta tarea, que está en permanente transformación y ac- tualización, sufrió un sismo en el 2020 y 2021 a partir de las condiciones devenidas por la pandemia. La Facultad de Artes por el tipo de conocimiento y metodología que proyecta, requiere de la presencialidad como plataforma de funcionamiento. Sin embargo, inmersos en la emergencia, les docentes, nodocentes, estudiantes y egresades re- aprendimos, reorganizamos y reinventamos dinámicas que nos permitieron seguir habilitando el derecho a la educación pública, a la creación de conocimiento especí- fico en artes y a la significación solidaria de los lazos societarios. Todos estos procesos implicaron un enorme trabajo colectivo que posibilitó diversas respuestas y abanicos de experiencias, creadas, procesadas, aplicadas y so- pesadas mientras transitábamos ese común estado pantallistico que habitábamos desde cada hogar por separado. El inicio del 2022 significó una nueva mutación, con sus consecuentes incerti- dumbres. Se abría una etapa marcada por la necesidad de consolidar una pedagogía de la presencia y de desarrollar otras didácticas de los cuerpos, recuperando la ale- gría del encuentro sin descuidar las lógicas de prevención en salud.Mohaded, Ana María. Universidad Nacional de Córdoba. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina.Domínguez Pesce, Agustín. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Música; Argentina.Salit, Celia. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Música; Argentina.Estarellas, Natalia. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Menoyo, Sofía G. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Argüello, Cecilia Beatriz. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Música; Argentina.Sajeva, Maura Jorgelina. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Teatro; Argentina.Irazusta, María Cecilia. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Otero Gruer, Dolores. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Mendizabal, Lilian Isabel. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Teatro; Argentina.Cáceres, Carlos Esteban. Universidad Nacional de Córdoba. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina.Fernández, Juan Manuel. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina.Menta, María Eugenia. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Música; Argentina.Hernández, Alejandra Fabiana. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Miranda, Adriana Esther. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Vivanco, Fernanda. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Teatro; Argentina.Serra, Mariela. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Teatro; Argentina.Altamirano, Ivana Verónica. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Teatro; Argentina.Bravo, Carolina. Universidad Nacional de Córdoba. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina.Jacobo, Mónica. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Artes Visuales; Argentina.Sequeira, Jazmín. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Teatro; Argentina.Suárez, Victoria Inés. Universidad Nacional de Córdoba. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina.Yaya Aguilar, María Marcela. Universidad Nacional de Córdoba. Facultad de Artes. Departamento Académico de Cine y Televisión; Argentina.Curletto, Hugo Daniel. Universidad Nacional de Córdoba. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina.Checchi, Pablo Martín. Universidad Nacional de Córdoba. Facultad de Artes.Departamento Académico de Cine y Televisión; Argentina

Impact of International Nosocomial Infection Control Consortium (INICC) strategy on central line-associated bloodstream infection rates in the intensive care units of 15 developing countries

BACKGROUND. The International Nosocomial Infection Control Consortium (INICC) was established in 15 developing countries to reduce infection rates in resource-limited hospitals by focusing on education and feedback of outcome surveillance (infection rates) and process surveillance (adherence to infection control measures). We report a time-sequence analysis of the effectiveness of this approach in reducing rates of central line-associated bloodstream infection (CLABSI) and associated deaths in 86 intensive care units with a minimum of 6-month INICC membership. METHODS. Pooled CLABSI rates during the first 3 months (baseline) were compared with rates at 6-month intervals during the first 24 months in 53,719 patients (190,905 central line-days). Process surveillance results at baseline were compared with intervention period data. RESULTS. During the first 6 months, CLABSI incidence decreased by 33% (from 14.5 to 9.7 CLABSIs per 1,000 central line-days). Over the first 24 months there was a cumulative reduction from baseline of 54% (from 16.0 to 7.4 CLABSIs per 1,000 central line-days; relative risk, 0.46 [95% confidence interval, 0.33-0.63]; P < .001). The number of deaths in patients with CLABSI decreased by 58%. During the intervention period, hand hygiene adherence improved from 50% to 60% (P < .001); the percentage of intensive care units that used maximal sterile barriers at insertion increased from 45% to 85% (P < .001 ), that adopted chlorhexidine for antisepsis increased from 7% to 27% (P=.018 ), and that sought to remove unneeded catheters increased from 37% to 83% (P=.004); and the duration of central line placement decreased from 4.1 to 3.5 days (P < .001). CONCLUSIONS. Education, performance feedback, and outcome and process surveillance of CLABSI rates significantly improved infection control adherence, reducing the CLABSI incidence by 54% and the number of CLABSI-associated deaths by 58% in INICC hospitals during the first 2 years. © 2010 by The Society for Healthcare Epidemiology of America. All rights reserved

International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015: Device-associated module

•We report INICC device-associated module data of 50 countries from 2010-2015.•We collected prospective data from 861,284 patients in 703 ICUs for 3,506,562 days.•DA-HAI rates and bacterial resistance were higher in the INICC ICUs than in CDC-NHSN's.•Device utilization ratio in the INICC ICUs was similar to CDC-NHSN's. Background: We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific. Methods: During the 6-year study period, using Centers for Disease Control and Prevention National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 861,284 patients hospitalized in INICC hospital ICUs for an aggregate of 3,506,562 days. Results: Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central line-associated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8 per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associated pneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheter-associated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples, frequencies of resistance of Pseudomonas isolates to amikacin (29.87% vs 10%) and to imipenem (44.3% vs 26.1%), and of Klebsiella pneumoniae isolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27% vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs. Conclusions: Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported in CDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the reduction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC's main goal to continue facilitating education, training, and basic and cost-effective tools and resources, such as standardized forms and an online platform, to tackle this problem effectively and systematically