8 research outputs found
Quantifying Uncertainty: Physicians' Estimates of Infection in Critically Ill Neonates and Children
To determine the diagnostic accuracy of physicians' prior probability estimates of serious infection in critically ill neonates and children, we conducted a prospective cohort study in 2 intensive care units. Using available clinical, laboratory, and radiographic information, 27 physicians provided 2567 probability estimates for 347 patients (follow-up rate, 92%). The median probability estimate of infection increased from 0% (i.e., no antibiotic treatment or diagnostic work-up for sepsis), to 2% on the day preceding initiation of antibiotic therapy, to 20% at initiation of antibiotic treatment (P < .001). At initiation of treatment, predictions discriminated well between episodes subsequently classified as proven infection and episodes ultimately judged unlikely to be infection (area under the curve, 0.88). Physicians also showed a good ability to predict blood culture-positive sepsis (area under the curve, 0.77). Treatment and testing thresholds were derived from the provided predictions and treatment rates. Physicians' prognoses regarding the presence of serious infection were remarkably precise. Studies investigating the value of new tests for diagnosis of sepsis should establish that they add incremental value to physicians' judgmen
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Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46102/1/168_2005_Article_BF01287326.pd
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An Application of the Almon Polynomial Lag to Residential Water Price Analysis
From the Proceedings of the 1982 Meetings of the Arizona Section - American Water Resources Assn. and the Hydrology Section - Arizona - Nevada Academy of Science - April 24,1982, Tempe, ArizonaThis article is part of the Hydrology and Water Resources in Arizona and the Southwest collections. Digital access to this material is made possible by the Arizona-Nevada Academy of Science and the University of Arizona Libraries. For more information about items in this collection, contact [email protected]