4,063 research outputs found
Pseudo-saturating power converter
Relative performance of three basic configurations of electronic conversion units (saturating, pseudo-saturating, nonsaturating) requiring low power levels is compared. Pseudo-saturating mode exhibits best overall performance, nonsaturating a close second, saturating a poor third
Dissociating object directed and non-object directed action in the human mirror system; implications for theories of motor simulation.
Mirror neurons are single cells found in macaque premotor and parietal cortices that are active during action execution and observation. In non-human primates, mirror neurons have only been found in relation to object-directed movements or communicative gestures, as non-object directed actions of the upper limb are not well characterized in non-human primates. Mirror neurons provide important evidence for motor simulation theories of cognition, sometimes referred to as the direct matching hypothesis, which propose that observed actions are mapped onto associated motor schemata in a direct and automatic manner. This study, for the first time, directly compares mirror responses, defined as the overlap between action execution and observation, during object directed and meaningless non-object directed actions. We present functional MRI data that demonstrate a clear dissociation between object directed and non-object directed actions within the human mirror system. A premotor and parietal network was preferentially active during object directed actions, whether observed or executed. Moreover, we report spatially correlated activity across multiple voxels for observation and execution of an object directed action. In contrast to predictions made by motor simulation theory, no similar activity was observed for non-object directed actions. These data demonstrate that object directed and meaningless non-object directed actions are subserved by different neuronal networks and that the human mirror response is significantly greater for object directed actions. These data have important implications for understanding the human mirror system and for simulation theories of motor cognition. Subsequent theories of motor simulation must account for these differences, possibly by acknowledging the role of experience in modulating the mirror response
Efficiency of using community organisations as catalysts for recruitment to continence promotion trials
This article is available open access through the publisher’s website from the link below. Copyright @ 2012 The Authors.Background - A major challenge for determining the effectiveness of community-based continence promotion campaigns is recruitment of a representative sample of incontinent participants who have not previously sought care.
Purpose - To evaluate the efficiency of engaging community organisations as catalysts for recruitment of community-dwelling older women with incontinence to the ‘Continence across Continents’ randomised controlled trial.
Methods - Seniors’ and women’s community-based organisations throughout the United Kingdom were solicited by telephone or email to assist recruitment for an open-label cluster randomised controlled trial testing three experimental continence promotion interventions and a control intervention for incontinent older women. Women aged 60 years and older who experienced at least weekly urinary incontinence and who had never sought treatment were eligible to participate. The response rate of the organisations and enrolment rate of eligible participants attending the continence promotion workshops were recorded. Differences in recruitment efficiency by intervention group were ascertained using analysis of variance statistics.
Results - We contacted 408 community organisations over a 1-year period. Seventy organisations (17%) agreed to host a workshop, 249 (61%) did not provide a response, and 89 (22%) refused. Workshops were administered in a group format to 61 organisations (15%); 667 women attended, 583 (87%) submitted the screening questionnaire, and 437 (66%) met eligibility criteria for inclusion. A total of 192 women consented to participate in the trial, yielding a 44% recruitment efficiency among workshop attendees known to be eligible, with no significant difference in enrolment rates between groups. However, the mean participant recruitment rate per number of attendees at each workshop was only 29%, varying substantially between groups from 19% to 37%, with the lowest rate observed for the control group. The mean annual recruitment rate expressed as the number of enrolled participants per community organisation contacted was 0.5.
Limitations - Reasons for women’s non-response were not collected. The findings may be country specific.
Conclusions - The recruitment rate for a continence promotion trial among older women known to be eligible and attending workshops hosted by local community organisations was high (44%). Strategies are needed to bolster community organisations’ involvement in health promotion trials in general and for continence issues in particular
Improvement of oxygen partial pressure sensor
Flight type calcium stabilized solid electrolyte oxygen senso
Methods for the evaluation of alternative disaster warning systems
For each of the methods identified, a theoretical basis is provided and an illustrative example is described. The example includes sufficient realism and detail to enable an analyst to conduct an evaluation of other systems. The methods discussed in the study include equal capability cost analysis, consumers' surplus, and statistical decision theory
Effectiveness of continence promotion for older women via community organisations: A cluster randomised trial
This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/Objectives: The primary objective of this cluster randomised controlled trial was to compare the effectiveness of the three experimental continence promotion interventions against a control intervention on urinary symptom improvement in older women with untreated incontinence recruited from community organisations. A second objective was to determine whether changes in incontinence-related knowledge and new uptake of risk-modifying behaviours explain these improvements.
Setting: 71 community organisations across the UK.
Participants: 259 women aged 60 years and older with untreated incontinence entered the trial; 88% completed the 3-month follow-up.
Interventions: The three active interventions consisted of a single 60 min group workshop on (1) continence education (20 clusters, 64 women); (2) evidence-based self-management (17 clusters, 70 women); or (3) combined continence education and self-management (17 clusters, 61 women). The control intervention was a single 60 min educational group workshop on memory loss, polypharmacy and osteoporosis (17 clusters, 64 women).
Primary and secondary outcome measures: The primary outcome was self-reported improvement in incontinence 3 months postintervention at the level of the individual. The secondary outcome was change in the International Consultation on Incontinence Questionnaire (ICIQ) from baseline to 3-month follow-up. Changes in incontinence-related knowledge and behaviours were also assessed.
Results: The highest rate of urinary symptom improvement occurred in the combined intervention group (66% vs 11% of the control group, prevalence difference 55%, 95% CI 43% to 67%, intracluster correlation 0). 30% versus 6% of participants reported significant improvement respectively (prevalence difference 23%, 95% CI 10% to 36%, intracluster correlation 0). The number-needed-to-treat was 2 to achieve any improvement in incontinence symptoms, and 5 to attain significant improvement. Compared to controls, participants in the combined intervention reported an adjusted mean 2.05 point (95% CI 0.87 to 3.24) greater improvement on the ICIQ from baseline to 3-month follow-up. Changes in knowledge and self-reported risk-reduction behaviours paralleled rates of improvement in all intervention arms.
Conclusions: Continence education combined with evidence-based self-management improves symptoms of incontinence among untreated older women. Community organisations represent an untapped vector for delivering effective continence promotion interventions.Canadian Institutes of Health Research – Institute on
Aging and the Economic and Social Research Council (UK
Methods for the evaluation of alternative disaster warning systems. Executive summary
Methods for estimating the economic costs and benefits of the transmission-reception and reception-action segments of a disaster warning system (DWS) are described. Methods were identified for the evaluation of the transmission and reception portions of alternative disaster warning systems. Example analyses using the methods identified were performed
Sintered aluminium heat pipe (SAHP)
This work is the product of an ongoing PhD project in the School of the Built and Natural Environment of Northumbria University in collaboration with the University of Liverpool and Thermacore Europe Ltd. The achievements at the end of the first year are summarized. The main objective of the project is to develop an aluminum ammonia heat pipe with a sintered wick structure. Currently available ammonia heat pipes mainly use extruded axially grooved aluminum tubes as a capillary wick. There have been a few attempts of employing porous steel or nickel wicks in steel tubes with ammonia as the working fluid (Bai, Lin et al. 2009)although it is a common practice in loop heat pipes but there is no report of aluminum-ammonia heat pipes porous aluminium wick structures. The main barrier is the difficulty of sintering aluminum powders to manufacture porous wicks. So far during this project promising sintered aluminum heat pipe samples have been manufactured using the Selective Laser Melting (SLM) technique with various wick characteristics. This SLM method has proven to be capable of manufacturing very complicated wick structures with different thickness, porosity, permeability and pore sizes in different regions of a heat pipe. In addition the entire heat pipe including the end cap, outer tube wall, wick and the fill tube can be generated in a single process
Need Fulfillment and Stay-Leave Behavior: On the Diagnosticity of Personal and Relational Needs.
Need fulfillment has been found to be associated with numerous positive relationship outcomes, but its impact on stay–leave behavior is less clear. In the current study, we considered whether the fulfillment of different needs might differentially affect stay–leave behavior. We distinguished between needs that are personal in nature and those that are relational in nature. Central to our theoretical analysis is the interdependence-based contention that the fulfillment of different kinds of needs provides diagnostic information regarding a partner’s motives and intentions regarding a relationship. Using two-wave longitudinal data obtained from romantically involved participants, we tested the relative fit of two alternative models that specified the associations between the fulfillment of different kinds of needs, commitment, and stay–leave behavior. Consistent with an interdependence approach, we found that the influence of the fulfillment of personal needs on stay–leave behavior was mediated by commitment, whereas the fulfillment of relational needs directly influenced stay–leave behavior. Implications for relationship functioning are considered
Recent Developments in Methods to Characterise the Chemical and Biological Parameters of Grass Silage
Key points Chemical analysis of forages is expensive, time consuming, environmentally unfriendly and relates poorly to the feed value for production purposes. In vivo characterisation of animal feed is not a feasible option in terms of cost and analysis time. NIRS is a rapid, non destructive, environmentally friendly, multi-analytical technique which can estimate the nutritive value of the feed. NIRS predictive equations developed on a master instrument can be transferred to local and international sites. Future assessment of forages necessitates rapid, stable, instrumentation for ‘in field’ studies
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