Life-time savings per each HIV infection averted.

a<p>Coverage assumptions come from published literature (WHO) and routine data/consensus discussions among HIV service providers in Rwanda.</p><p>PLHIV, people living with HIV/AIDS; TB, tuberculosis.</p

Effectiveness of neonatal, adolescent, and adult MC in Rwanda, 2008.

a<p>The incidence rates are multiplied by cohorts of 150,000, minus the number of infections that occurred previously.</p

Savings for neonatal, adolescent, and adult MC in Rwanda, 2008.

<p>Savings for neonatal, adolescent, and adult MC in Rwanda, 2008.</p

Costs standardised to one MC procedure for a cohort of 150,000 adults and 150,000 newborns in Rwanda, 2008.

<p>Base case year, 2008.</p>a<p>The costs of a promotion campaign for a circumcision program that targeted infants, adolescent, and adults would be less than the sum of the individual campaigns, which would increase the cost-effectiveness of each if implemented jointly.</p>b<p>Dorsal slit method (reflecting current practice in Kigali) in hospital.</p

Threshold analysis.

<p>Threshold analysis.</p

Odor levels for each arm determined by operators.

<p>Odor levels for each arm determined by operators.</p

Odor levels for each arm determined by blinded smellers on day 7.

<p>Odor levels for each arm determined by blinded smellers on day 7.</p

Subjects’ feedback during day 7 visit.

<p>Subjects’ feedback during day 7 visit.</p

The Nasal Ranger device.

<p>The Nasal Ranger device.</p

Flow of participants in the trial.

<p>Flow of participants in the trial.</p