43 research outputs found

    Dirac Equation with Spin Symmetry for the Modified P\"oschl-Teller Potential in DD-dimensions

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    We present solutions of the Dirac equation with spin symmetry for vector and scalar modified P\"oschl-Teller potential within framework of an approximation of the centrifugal term. The relativistic energy spectrum is obtained using the Nikiforov-Uvarov method and the two-component spinor wavefunctions are obtain are in terms of the Jacobi polynomials. It is found that there exist only positive-energy states for bound states under spin symmetry, and the energy levels increase with the dimension and the potential range parameter α\alpha.Comment: 9 pages and 1tabl

    Registration of cancer in girls remains lower than expected in countries with low/middle incomes and low female education rates.

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    BACKGROUND: A decade ago it was reported that childhood cancer incidence was higher in boys than girls in many countries, particularly those with low gross domestic product (GDP) and high infant mortality rate. Research suggests that socio-economic and cultural factors are likely to be responsible. This study aimed to investigate the association between cancer registration rate sex ratios and economic, social and healthcare-related factors using recent data (1998-2002). METHODS: For 62 countries, childhood (0-15 years) cancer registration rate sex ratios were calculated from Cancer Incidence in Five Continents Vol IX, and economic, social and healthcare indicator data were collated. RESULTS: Increased age standardised cancer registration rate sex ratio (M:F) was significantly associated with decreasing life expectancy (P=0.05), physician density (P=0.05), per capita health expenditure (P=0.05), GDP (P=0.01), education sex ratios (primary school enrolment sex ratio (P<0.01); secondary school enrolment sex ratio (P<0.01); adult literacy sex ratio (P<0.01)) and increasing proportion living on less than Int$1 per day (P=0.03). CONCLUSION: The previously described cancer registration sex disparity remains, particularly, in countries with poor health system indicators and low female education rates. We suggest that girls with cancer continue to go undiagnosed and that incidence data, particularly in low- and middle-income countries, should continue to be interpreted with caution

    Family doctor-driven follow-up for adult childhood cancer survivors supported by a web-based survivor care plan

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    To facilitate family doctor-driven follow-up for adult childhood cancer survivors, we developed a survivor care plan (SCP) for adult survivors and their family doctors. The SCP was accessible for survivors and their family doctors on a secure website and as a printed booklet. It included data on diagnosis, treatment and potential risks as well as recommendations for follow-up. Childhood cancer survivors who were off-treatment >= 5 years, aged >= 18 years and not involved in a long-term follow-up program were eligible. They were advised to visit their family doctor. The endpoints were numbers of participants, adherence of family doctors to the guidelines and satisfaction ratings. The eligibility criteria were fulfilled by 108 survivors. Three family doctors and 15 survivors refused, 10 survivors were non-responders. Of the remaining 80 survivors, 73 survivors visited 72 family doctors. Sixty-nine (96%) family doctors returned data of whom 60 (83%) fully adhered to the recommended tests. The majority of survivors and family doctors were satisfied about the SCP. A (web-based) SCP for survivors and family doctors can serve as an effective communication vehicle to provide adequate shared care by the long-term follow-up clinic and family doctors

    Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

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    Background: Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. // Methods: We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung's disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. // Findings: We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung's disease) from 264 hospitals (89 in high-income countries, 166 in middle-income countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in low-income countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. // Interpretation: Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between low-income, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

    Prescription pattern and prevalence of potentially inappropriate medications among elderly patients in a Nigerian rural tertiary hospital

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    Joseph O Fadare,1 Segun Matthew Agboola,2 Olumide Augustine Opeke,3 Rachel A Alabi41Department of Medical Pharmacology and Therapeutics, Obafemi Awolowo University, Ile-Ife, Nigeria; 2Department of Family Medicine, 3Department of Internal Medicine, 4Pharmacy Department, Federal Medical Centre, Ido-Ekiti, NigeriaIntroduction: Polypharmacy and inappropriate prescriptions are prominent prescribing issues with elderly patients. Beers criteria and other guidelines have been developed to assist in the reduction of potentially inappropriate medications prescribed to elderly patients. The objectives of this study were to assess the prescribing pattern for elderly Nigerian outpatients and estimate the prevalence of potentially inappropriate medications among them using the Beers criteria.Methodology: This was a prospective cross-sectional study of elderly patients (65 years and above) who were attending the general outpatients clinic of a rural Nigerian hospital. For the drug utilization aspect of the study, drug-use indicators were assessed using established World Health Organization guidelines, while the Beers criteria was used to screen for potentially inappropriate medications.Result: The medical records of 220 patients aged 65 years and above were utilized for the study. A total of 837 drugs were prescribed for the patients, giving an average of 3.8 &amp;plusmn; 1.3 drugs per person. Antihypertensive drugs accounted for 30.6% of the prescriptions, followed by multivitamins/food supplements (11.5%) and analgesics (10.8%). A review of the prescribed medications using the 2012 Updated Beers Criteria by the American Geriatric Society identified 56 patients with at least one potentially inappropriate medication prescribed giving a rate of 25.5%. The drug groups identified were nonsteroidal anti-inflammatory drugs, antihistamines, and amitriptyline.Conclusion: Polypharmacy and prescription of potentially inappropriate medications are major therapeutic issues in Nigeria. There is a need for prescriber training and retraining with emphasis on the geriatric population.Keywords: drug utilization pattern, elderly patients, rational use of medicines, adverse drug reactions, Beers criteri

    Perception of stroke among patients with stroke

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    The perception of patients to stroke is variable. The aim of this study was to determine the perception of stroke among stroke patients. The study was carried out between January 2004 - December 2004 on all the patients presenting with features of stroke at the Federal Medical Center Ido, Nigeria. Data were collected by administering a set of questionnaire to the patients and/or relations. A total of 68 patients were studied, mean age of the patients was 66+3.5 years. High blood pressure was the most common risk factor for stroke identified. Majority of the patients were able to recognize at least one stroke symptom and presented after 48 hours of the onset of stroke symptoms. Patients' perception, lack of transportation, financial constraints and ignorance adversely affected their presentation to the hospital. Delays in patients arriving at hospital with suspected stroke can be reduced by increased awareness. Simple and understandable educational materials should be developed for at risk groups and the entire populace. Keywords: stroke, high blood pressure, diabetes Nigerian Medical Practitioner Vol. 48(2) 2005: 56-5

    Chest X-Ray in Family Practice

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    Relationship between family support and quality of life of type-2 diabetes mellitus patients attending family medicine clinic, federal medical centre, Ido–Ekiti.

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    Background: Diabetes mellitus is a chronic disease with increase morbidity and mortality. It could be associated with significant adverse outcomes including poor quality of life. In Sub-Saharan Africa, Nigeria has a large share of the morbidity and mortality of DM. Several factors have been found to be associated with better quality of life among diabetes mellitus (DM) patients. There is a dearth of local research work on the relationship of family support and quality of life of this group of patients.Objective: This study sought to determine the relationship between family support and quality of life of type 2 diabetes mellitus patients attending family medicine clinic, Federal Medical Centre, Ido-Ekiti, Ekiti State, Nigeria.Materials and Methods: A cross-sectional study of 250 adult patients with type 2 diabetes mellitus was carried out over twenty (20) weeks. Respondents' family support was measured using Perceived Social Support – Family Scale {PSS- Fa}, while their quality of life was measured using the short version of the World Health Organization quality of life assessment tool (WHOQOL-BREF).Results: The level of family support was significantly associated with quality of life at p-value less than 0.001. Majority [n = 104 (59.8%)] of the respondents who reported having strong family support had fair quality of life. Also, a significant percentage (85.7%) of all respondents who had good quality of life were found to have strong family support. The converse was true of respondents with poor quality of life as only 5(10.4%) of them reported having strong family support. Also, majority [n = 33 (68.8%)] of respondents with poor quality of life reported having weak family support. Strong family support was an independent predictor of good quality of life among study participants. Respondents with strong family support were 14 times more likely to have good quality of life than those with no family support.Conclusion: Good family support positively correlated with better quality of life of respondents. Hence, Family Physicians should utilise this resource by advocating for an active involvement of family members in management plans of DM patients to enhance their quality of life

    Pattern of Family Support among HIV Patients in a Tertiary Health Center in Southwest Nigeria

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    Background: The impact of the HIV/AIDS pandemic on the social and economic development of Nigeria has been substantial. Adequate family support remains a critical factor for the achievement of optimal HIVcare. This study investigated the level and pattern of family support received by people living with HIV/AIDS (PLWHA).Method: A descriptive, cross-sectional study was carried out among PLWHAs receiving care within the family practice at the Federal Medical Centre, Ido-Ekiti, Nigeria. Respondents were selected using systematic random sampling technique. A structured, interviewer-administered questionnaire was used to collect data from the respondents. Data was analysed using SPSS version 16.0.Result: A total of one hundred (100) PLWHA were interviewed. Their mean age was 43.0 (SD12.0) years. Sixty-one per cent (61.0%) were females. A greater proportion of the subjects (81%) were married. Monogamous family structure was observed in 72% of all the subjects. Family support was strong amongst 85% and a significant positive association was found between family support and age (p=0.008), family structure (p=0.003) and marital status (p=0.000).Conclusion: Most PLWHA studied had strong family support. Middle age and being married in a monogamous family setup were significant factors for this support. Family involvement and support during initiation and continuation of their antiretroviral therapy is recommended.Keywords: Family Support; ART; HIV/AIDS; PLWHAs; Nigeri
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