Pengaruh Aplikasi Gel Metronidazol Sebagai Terapi Adjuvant Paska Kuretase pada Periodontitis Kronis (Literature Review)

Chronic periodontitis is often characterized by the presence of periodontal pockets. Scaling treatments, root planing, curettage and good oral hygiene will eliminate inflammation and reduce pocket depth. The use of metronidazole gel as a topical antimicrobial has a role in the healing of post-curettage periodontal pockets. The purpose of this literature review was to determine the effect of metronidazole gel application on post-curettage periodontal pocket healing in chronic periodontitis. This literature review uses the PICO method, namely PICO which stands for (P) Population, (I) Intervention, (C) Comparison, (O) Outcome. The population in this literature review is chronic periodontitis patients, the intervention is patients with metronidazole gel antibiotic treatment, the comparison is that adjuvant therapy is given metronidazole gel application and without metronidazole gel application, while the results or outcomes to be obtained are the effect of metronidazole gel application on the healing of periodontal pockets. post curettage in chronic periodontitis. The initial search was carried out from November to March 2021 through six search engines, namely: (1) Google Scholar (2) PubMed, (3) ScienceDirect, (4) Wiley, (5) ProQuest and (6) Springer. The keywords used in the search process were Metronidazole Gel, Curettage, Pocket Healing, Chronic Periodontitis. The results of this study indicate that the application of metronidazole gel has an effect on the healing of post-curettage periodontal pockets. Metronidazole gel has bactericidal properties that can kill anaerobic bacteria that play a role in periodontal disease