HUBUNGAN ANTARA STATUS RESEPTOR HORMONAL DENGAN DURASI LAKTASI PADA PASIEN KANKER PAYUDARA DI RSUD DR. SOETOMO

Background: Breast cancer is the most common cancer in woman with a high percentage of new cases and highest mortality rate. Breast cancer is characterized by abnormal cell development, tissue invasion, and metastasize from the origin cell to other body parts. Breast cancer is affected by hormonal receptor status such as Estrogen Receptor (ER) and Progesteron Receptor (PR). Lactation is a metabolic and reproductive process of a woman in which mammary glands proliferate and produce milk. In 2016, WHO recommended exclusive duration of lactation for the first 6 months without food supplements and continues for up to 2 years. Objective: To analyze the correlation of hormonal receptor status and lactation duration of breast cancer patients in Dr. Soetomo General Hospital Methods: This research was designed in crosssectional which observe breast cancer patients in Poli Onkologi Satu Atap (POSA) RSUD Dr. Soetomo from 1 January 2017– 28 February 2017. Age, parity, age at first birth, and duration of lactation were examined in both case and control group. Results: These findings suggest that age, parity, and age at first birth had no significant difference value between duration of lactation equal to 18 months or more and duration of lactation less than 18 months (p= 0,931, p=0,354, p= 0,460). Duration of lactation equal to 18 months or more has higher percentage of ER+ and/or PR+ hormonal receptor status compared to ER- and PR- in breast cancer patients (OR= 9,412; CI 95% 3,402-26,037; p=0.001). Conclusion: Duration of lactation had significant difference with hormonal receptor status

Risk Factors Of Hypertension In Rural Indonesia: A Crosssectional Study From A Rural Village In Indonesia

Aim: To determine the risk factors of hypertension in rural Indonesia. Methods: A cross-sectional study was conducted in a rural district in East Java, Indonesia. Using the modified WHO STEPwise approach to chronic disease risk factor surveillance (STEPS) questionnaire, variables related to the risk factors of hypertension were collected. Acquired data was analysed for significance using SPSS ver. 23.0 (IBM Corp, Armonk, USA). Results: A total of 103 respondents participated in this study. The prevalence of hypertension in this study was 35.92%. Old age (OR = 8.25, CI 95% 1.69 - 40.31) and obesity (OR = 6.18, CI 95% 2.09 - 18.32) was found to be a significant risk factor of hypertension. While gender, education level, occupation, physical activity, and smoking habits were considered not significant. Conclusion: Prevalence of hypertension in rural Indonesia is still high. This study highlighted age and body mass index as the significant risk factors of hypertension