37 research outputs found
ΠΠΠΠΠΠΠΠ§ΠΠ‘ΠΠΠ ΠΠ ΠΠΠ A (H1N1) PDM 09 Π ΠΠΠΠΠ‘ΠΠΠΠ 2015/2016 ΠΠ.: ΠΠΠΠΠΠ ΠΠΠ’ΠΠΠ¬ΠΠ«Π₯ ΠΠ‘Π₯ΠΠΠΠ Π£ ΠΠΠ’ΠΠ
The analysis of the characteristics of the current influenza A(H1N1) pdm 09 at 624 children in the 2015/2016 season. For severe illness (5%) characterized by short incubation period, lack of initial period, acute or acute onset with rapid development of multiorgan failure, prolonged febrile body temperature (up to 5β6 days or more) in the absence of complications, a prolonged severe intoxication (4β5 days or more), a significant frequency of diarrhea syndrome (10,2%), hemorrhagic syndrome (5.3%), exacerbation of comorbidity (20%), combinedΒ with other viral infectionsΒ β herpes, rotavirus, enterovirus and others (33%).In the clinical analysis of blood β leukopenia (33.9%), leukocytosis (14.5%) with neutrophilicΒ shift (11.3%), neutrophilia (51.6%), monocytosis (45.2%), lymphocytosis (9.7%), thrombocytopenia, anemia, accelerated erythrocyte sedimentation rate moderately; in the biochemical analysis of blood, hypernatremia, increase in the concentration of lactate, hyperfermentemia (ALT, AST, ALP, LDH, CPK), hypoproteinemia, dysproteinemia, increased CRP, increased creatinine and urea, increase of procalcitonin (PCT). In the structure of complications of pneumonia was 6%, stenosing laryngotracheitis β 9.8%, obstructive bronchitis β 14.5%. Two unvaccinated against influenza in infants who become ill during the epidemic period for influenza and SARS from homes with a typical clinical picture, died from severe (toxic) form of pandemic influenza. Pandemic influenza occurred at the background of severe immunosuppression (atrophy of the thymus, depletionΒ of follicles of peripheral organs of immunogenesis β spleen, lymph nodes, tonsils). The main cause of death was the development of multiple organ failure with rapid progressive lesion of the vital organs.Β ΠΡΠΎΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠ΅ΠΉ ΡΠ΅ΡΠ΅Π½ΠΈΡ Π³ΡΠΈΠΏΠΏΠ° A (H1N1) pdm 09 Ρ 624 Π΄Π΅ΡΠ΅ΠΉ Π² ΡΠΏΠΈΠ΄ΡΠ΅Π·ΠΎΠ½ 2015/2016 Π³Π³. ΠΡΠΈ ΡΡΠΆΠ΅Π»ΠΎΠΉ ΡΠΎΡΠΌΠ΅ Π±ΠΎΠ»Π΅Π·Π½ΠΈ (5%) ΠΎΡΠΌΠ΅ΡΠ°ΡΡΡΡ: ΠΊΠΎΡΠΎΡΠΊΠΈΠΉ ΠΈΠ½ΠΊΡΠ±Π°ΡΠΈΠΎΠ½Π½ΡΠΉ ΠΏΠ΅ΡΠΈΠΎΠ΄, ΠΎΡΡΡΡΡΡΠ²ΠΈΠ΅ Π½Π°ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΠ΅ΡΠΈΠΎΠ΄Π°, ΠΎΡΡΡΠΎΠ΅ ΠΈΠ»ΠΈ ΠΎΡΡΡΠ΅ΠΉΡΠ΅Π΅ Π½Π°ΡΠ°Π»ΠΎ Ρ Π±ΡΡΡΡΡΠΌ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ΠΌ ΠΏΠΎΠ»ΠΈΠΎΡΠ³Π°Π½Π½ΠΎΠΉ Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎΡΡΠΈ, Π΄Π»ΠΈΡΠ΅Π»ΡΠ½Π°Ρ ΡΠ΅Π±ΡΠΈΠ»ΡΠ½Π°Ρ ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΠ° ΡΠ΅Π»Π° (Π΄ΠΎ 5β6 ΡΡΡΠΎΠΊ ΠΈ Π±ΠΎΠ»Π΅Π΅) ΠΏΡΠΈ ΠΎΡΡΡΡΡΡΠ²ΠΈΠΈ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ,Β Π²ΡΡΠ°ΠΆΠ΅Π½Π½Π°Ρ Π΄Π»ΠΈΡΠ΅Π»ΡΠ½Π°Ρ ΠΈΠ½ΡΠΎΠΊΡΠΈΠΊΠ°ΡΠΈΡ (4β5 ΡΡΡΠΎΠΊ ΠΈ Π±ΠΎΠ»Π΅Π΅), Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½Π°Ρ ΡΠ°ΡΡΠΎΡΠ° ΡΠΈΠ½Π΄ΡΠΎΠΌΠ° Π΄ΠΈΠ°ΡΠ΅ΠΈ (10,2%), ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ Π³Π΅ΠΌΠΎΡΡΠ°Π³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠΈΠ½Π΄ΡΠΎΠΌΠ° (5,3%), ΠΎΠ±ΠΎΡΡΡΠ΅Π½ΠΈΠ΅ ΡΠΎΠΏΡΡΡΡΠ²ΡΡΡΠ΅ΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ (20%), ΡΠΎΡΠ΅ΡΠ°Π½ΠΈΠ΅ Ρ Π΄ΡΡΠ³ΠΈΠΌΠΈ Π²ΠΈΡΡΡΠ½ΡΠΌΠΈ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΡΠΌΠΈ β Π³Π΅ΡΠΏΠ΅ΡΠ²ΠΈΡΡΡΠ½ΠΎΠΉ, ΡΠΎΡΠ°Π²ΠΈΡΡΡΠ½ΠΎΠΉ, ΡΠ½ΡΠ΅ΡΠΎΠ²ΠΈΡΡΡΠ½ΠΎΠΉ ΠΈ Π΄Ρ. (33%).Π ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΌΒ Π°Π½Π°Π»ΠΈΠ·Π΅ ΠΊΡΠΎΠ²ΠΈ ΠΎΡΠΌΠ΅ΡΠ°ΡΡΡΡ Π»Π΅ΠΉΠΊΠΎΠΏΠ΅Π½ΠΈΡ (33,9%), Π»Π΅ΠΉΠΊΠΎΡΠΈΡΠΎΠ· (14,5%) Ρ Π½Π΅ΠΉΡΡΠΎΡΠΈΠ»ΡΠ½ΡΠΌ ΡΠ΄Π²ΠΈΠ³ΠΎΠΌ (11,3%), Π½Π΅ΠΉΡΡΠΎΡΠΈΠ»Π΅Π· (51,6%), ΠΌΠΎΠ½ΠΎΡΠΈΡΠΎΠ· (45,2%), Π»ΠΈΠΌΡΠΎΡΠΈΡΠΎΠ· (9,7%), ΡΡΠΎΠΌΠ±ΠΎΡΠΈΡΠΎΠΏΠ΅Π½ΠΈΡ, Π°Π½Π΅ΠΌΠΈΡ, ΡΠΌΠ΅ΡΠ΅Π½Π½ΠΎ ΡΡΠΊΠΎΡΠ΅Π½Π½Π°Ρ Π‘ΠΠ; Π² Π±ΠΈΠΎΡ
ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΎΠΌ Π°Π½Π°Π»ΠΈΠ·Π΅ ΠΊΡΠΎΠ²ΠΈΒ β Π³ΠΈΠΏΠ΅ΡΠ½Π°ΡΡΠΈΠ΅ΠΌΠΈΡ, Π½Π°ΡΠ°ΡΡΠ°Π½ΠΈΠ΅ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ Π»Π°ΠΊΡΠ°ΡΠ°, Π³ΠΈΠΏΠ΅ΡΡΠ΅ΡΠΌΠ΅Π½ΡΠ΅ΠΌΠΈΡ (ΠΠΠ’, ΠΠ‘Π’, Π©Π€, ΠΠΠ, ΠΠ€Π), Π³ΠΈΠΏΠΎΠΏΡΠΎΡΠ΅ΠΈΠ½Π΅ΠΌΠΈΡ, Π΄ΠΈΡΠΏΡΠΎΡΠ΅ΠΈΠ½Π΅ΠΌΠΈΡ, ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΠ΅ Π‘Π Π, ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΠ΅ ΠΊΡΠ΅Π°ΡΠΈΠ½ΠΈΠ½Π° ΠΈ ΠΌΠΎΡΠ΅Π²ΠΈΠ½Ρ, ΡΠ²Π΅Π»ΠΈΡΠ΅Π½ΠΈΠ΅ ΠΏΡΠΎΠΊΠ°Π»ΡΡΠΈΡΠΎΠ½ΠΈΠ½Π° (ΠΠΠ’). Π ΡΡΡΡΠΊΡΡΡΠ΅Β ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉΒ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠΈΒ ΡΠΎΡΡΠ°Π²ΠΈΠ»ΠΈ 6%, ΡΡΠ΅Π½ΠΎΠ·ΠΈΡΡΡΡΠΈΠ΅ Π»Π°ΡΠΈΠ½Π³ΠΎΡΡΠ°Ρ
Π΅ΠΈΡΡΒ βΒ 9,8%, ΠΎΠ±ΡΡΡΡΠΊΡΠΈΠ²Π½ΡΠ΅Β Β Π±ΡΠΎΠ½Ρ
ΠΈΡΡΒ β 14,5%. ΠΠ²ΠΎΠ΅ Π½Π΅ΠΏΡΠΈΠ²ΠΈΡΡΡ
ΠΏΡΠΎΡΠΈΠ² Π³ΡΠΈΠΏΠΏΠ° Π΄Π΅ΡΠ΅ΠΉ ΡΠ°Π½Π½Π΅Π³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ°, Π·Π°Π±ΠΎΠ»Π΅Π²ΡΠΈΠ΅ Π² ΡΠΏΠΈΠ΄Π΅ΠΌΠΈΡΠ΅ΡΠΊΠΈΠΉ ΠΏΠ΅ΡΠΈΠΎΠ΄ ΠΏΠΎ Π³ΡΠΈΠΏΠΏΡ, ΠΈΠ· ΡΠ΅ΠΌΠ΅ΠΉΠ½ΡΡ
ΠΎΡΠ°Π³ΠΎΠ² ΠΠ ΠΠ, Ρ ΡΠΈΠΏΠΈΡΠ½ΠΎΠΉ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΊΠ°ΡΡΠΈΠ½ΠΎΠΉ, ΡΠΌΠ΅ΡΠ»ΠΈ ΠΎΡ ΡΡΠΆΠ΅Π»ΠΎΠΉ (ΡΠΎΠΊΡΠΈΡΠ΅ΡΠΊΠΎΠΉ) ΡΠΎΡΠΌΡ ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π³ΡΠΈΠΏΠΏΠ°. ΠΠ°Π½Π΄Π΅ΠΌΠΈΡΠ΅ΡΠΊΠΈΠΉ Π³ΡΠΈΠΏΠΏ ΠΏΡΠΎΡΠ΅ΠΊΠ°Π» Π½Π° ΡΠΎΠ½Π΅ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΠΉ ΠΈΠΌΠΌΡΠ½ΠΎΡΡΠΏΡΠ΅ΡΡΠΈΠΈ (Π°ΡΡΠΎΡΠΈΡ ΡΠΈΠΌΡΡΠ°, ΠΈΡΡΠΎΡΠ΅Π½ΠΈΠ΅ ΡΠΎΠ»Π»ΠΈΠΊΡΠ»ΠΎΠ² ΠΏΠ΅ΡΠΈΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΎΡΠ³Π°Π½ΠΎΠ² ΠΈΠΌΠΌΡΠ½ΠΎΠ³Π΅Π½Π΅Π·Π° β ΡΠ΅Π»Π΅Π·Π΅Π½ΠΊΠΈ, Π»ΠΈΠΌΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ·Π»ΠΎΠ², ΠΌΠΈΠ½Π΄Π°Π»ΠΈΠ½). ΠΡΠ½ΠΎΠ²Π½ΠΎΠΉ ΠΏΡΠΈΡΠΈΠ½ΠΎΠΉ ΡΠΌΠ΅ΡΡΠΈ ΡΠ²ΠΈΠ»ΠΎΡΡ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ ΠΏΠΎΠ»ΠΈΠΎΡΠ³Π°Π½Π½ΠΎΠΉ Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎΡΡΠΈ Ρ Π±ΡΡΡΡΡΠΌ ΠΏΡΠΎΠ³ΡΠ΅ΡΡΠΈΡΡΡΡΠΈΠΌ ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΠ΅ΠΌ ΠΆΠΈΠ·Π½Π΅Π½Π½ΠΎ Π²Π°ΠΆΠ½ΡΡ
ΠΎΡΠ³Π°Π½ΠΎΠ²
Cancer of the tongue and floor of the mouth: Current aspects of diagnosis
The diagnosis and treatment of cancer of the tongue and floor of the mouth is a relevant problem, for 60β80% of patients first seek medical treatment only when they have late stages of the disease. The review analyzes the data available in the Russian and foreignliterature on mainstay techniques for radiodiagnosing cancer of the mouth and floor of the mouth. It highlights the capabilities of computed tomography in diagnosing this pathology, in assessing deepseated anatomic structures of the mouth and floor of the mouth, and in detecting metastatic neck lymph nodes
PANDEMIC INFLUENZA A (H1N1) PDM 09 IN THE SEASON 2015/2016: ANALYSIS OF FATAL OUTCOMES IN CHILDREN
The analysis of the characteristics of the current influenza A(H1N1) pdm 09 at 624 children in the 2015/2016 season. For severe illness (5%) characterized by short incubation period, lack of initial period, acute or acute onset with rapid development of multiorgan failure, prolonged febrile body temperature (up to 5β6 days or more) in the absence of complications, a prolonged severe intoxication (4β5 days or more), a significant frequency of diarrhea syndrome (10,2%), hemorrhagic syndrome (5.3%), exacerbation of comorbidity (20%), combinedΒ with other viral infectionsΒ β herpes, rotavirus, enterovirus and others (33%).In the clinical analysis of blood β leukopenia (33.9%), leukocytosis (14.5%) with neutrophilicΒ shift (11.3%), neutrophilia (51.6%), monocytosis (45.2%), lymphocytosis (9.7%), thrombocytopenia, anemia, accelerated erythrocyte sedimentation rate moderately; in the biochemical analysis of blood, hypernatremia, increase in the concentration of lactate, hyperfermentemia (ALT, AST, ALP, LDH, CPK), hypoproteinemia, dysproteinemia, increased CRP, increased creatinine and urea, increase of procalcitonin (PCT). In the structure of complications of pneumonia was 6%, stenosing laryngotracheitis β 9.8%, obstructive bronchitis β 14.5%. Two unvaccinated against influenza in infants who become ill during the epidemic period for influenza and SARS from homes with a typical clinical picture, died from severe (toxic) form of pandemic influenza. Pandemic influenza occurred at the background of severe immunosuppression (atrophy of the thymus, depletionΒ of follicles of peripheral organs of immunogenesis β spleen, lymph nodes, tonsils). The main cause of death was the development of multiple organ failure with rapid progressive lesion of the vital organs
GENERALIZED TUBERCULOSIS WITH SPINAL LESIONS IN HIV PATIENTS
Π£Β Π±ΠΎΠ»ΡΠ½ΡΡ
ΡΒ ΡΠΎΡΠ΅ΡΠ°Π½Π½ΠΎΠΉ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ Π½Π°Β ΠΏΠΎΠ·Π΄Π½ΠΈΡ
ΡΡΠ°Π΄ΠΈΡΡ
ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΈ ΠΌΠ΅Π½ΡΠ΅ΡΡΡ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡ ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Π½ΠΎΠ³ΠΎ Π²ΠΎΡΠΏΠ°Π»Π΅Π½ΠΈΡ, ΠΏΡΠΈΠΎΠ±ΡΠ΅ΡΠ°ΡΡΠ΅Π³ΠΎ Π³Π΅Π½Π΅ΡΠ°Π»ΠΈΠ·ΠΎΠ²Π°Π½Π½ΡΠΉ Ρ
Π°ΡΠ°ΠΊΡΠ΅Ρ, ΠΏΡΠΎΡΠ΅ΠΊΠ°Ρ ΠΏΠΎΒ ΡΠΈΠΏΡ ΡΠ΅ΠΏΡΠΈΡΠ° ΡΒ Π²ΠΎΠ²Π»Π΅ΡΠ΅Π½ΠΈΠ΅ΠΌ 5-6 ΠΎΡΠ³Π°Π½ΠΎΠ². ΠΠ»ΠΈΠ½ΠΈΠΊΠΎ-ΡΠ΅Π½ΡΠ³Π΅Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΡΠΎΡΠ²Π»Π΅Π½ΠΈΡ ΡΡΠ°Π½ΠΎΠ²ΡΡΡΡ Π°ΡΠΈΠΏΠΈΡΠ½ΡΠΌΠΈ [3,Β 5], ΡΡΠΎ ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΡ ΠΊΒ Π½Π΅ΡΠ²ΠΎΠ΅Π²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠ΅ ΡΠΎΡΠ΅ΡΠ°Π½Π½ΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈΒ β ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΡ ΠΈΒ ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Β β Π²Β 58,3% ΡΠ»ΡΡΠ°Π΅Π² [6]