Prevalence of LTBI according to the time of exposure of 0, 1, 3, 6 and 12 months and the MTC-score values of 4, 8, 13 and 15 in children up to 6 years of age in Manaus, Brazil.

<p>MTC-SCORE: <i>Mycobacterium tuberculosis</i> contact score.</p

Estimation of the sensitivity and specificity of QFT and TST, and the coefficients of regression of the variables of time of exposure and MTC-Score associated with the prevalence (second phase).

<p>Estimation of the sensitivity and specificity of QFT and TST, and the coefficients of regression of the variables of time of exposure and MTC-Score associated with the prevalence (second phase).</p

Flow diagram of enrollment.

<p>TB: tuberculosis, QFT: QuantiFERON-TB Gold In-Tube, TST: Tuberculin Skin Test.</p

Probability of LTBI in children up to 6 years of age according to the results of both tests in the latent class model (first phase).

<p>Probability of LTBI in children up to 6 years of age according to the results of both tests in the latent class model (first phase).</p

Probability of non LTBI (LTBI^c) in children up to 6 years of age according to the results of both tests in the latent class model (first phase).

<p>Probability of non LTBI (LTBI^c) in children up to 6 years of age according to the results of both tests in the latent class model (first phase).</p

Results of the prevalence of LTBI according to exposure to an index TB case and the sensitivity and the specificity of QFT and TST in children up to 6 years of age in Manaus, Brazil (first phase).

<p>Results of the prevalence of LTBI according to exposure to an index TB case and the sensitivity and the specificity of QFT and TST in children up to 6 years of age in Manaus, Brazil (first phase).</p

Odds ratio and confidence interal of 95% for the Tuberculosis Skin Test positive results according to time of exposure (months) to index case.

<p>Odds ratio and confidence interal of 95% for the Tuberculosis Skin Test positive results according to time of exposure (months) to index case.</p

Multivariate logistic regression according to factors for positive QFT results stratified by TST results.

<p>TST: Tuberculin Skin Test, QFT: QuantiFERON-TB Gold In-Tube, MTC-score: <i>Mycobacterium tuberculosis</i> contact score, BCG: Bacillus Calmette-Guérin.</p>a<p>logistic regression coefficient related to quantitative variable.</p>b<p>Linear odds ratio; exponential to the regression coefficient.</p

MOESM2 of Immune response pattern in recurrent Plasmodium vivax malaria

Additional file 2. Ex vivo phenotypic features of circulating NK and NKT, Treg and B-cells. The levels lymphocyte subsets were assessed in patients with primary malaria, recurrent malaria as well as endemic controls, including: A) NK-cells; B) NKT-cells; C) Treg-cells; D) B-cells; and E) B1-cells. Data are displayed in boxplot format (min to max, IQR25-IQR75 and median). Multiple comparisons amongst clinical groups were performed by Kruskal–Wallis, followed by Dunn’s post-test. Significance differences are represented by * for p < 0.05; ** for p < 0.005 and *** for p < 0.000

Comparison of the TST and QFT results.

<p>TST: Tuberculin Skin Test, QFT: QuantiFERON-TB Gold In-Tube, n: number of subjects.</p