Association of the rs6232 and rs6235 with obesity in children and adult populations.

<p>Data are n (%). All odds ratios and <i>P</i>-values were calculated by logistic regression analyses using non-obese individuals as reference group, adjusting for age, sex and DT2. <i>P</i>_add, <i>P</i>-values for the additive model.</p

Glucose homeostasis parameters in nondiabetic children and adult populations according to <i>PCSK1</i> rs6232.

<p>Data are means ± s.d. or medians (interquantile range). <i>P</i>-values were calculated by generalized linear regression. BMI was adjusted for age and gender. Plasma glucose/insulin levels and HOMA indices were adjusted for age, gender and BMI. HOMA-B, homeostasis model assessment of beta-cell function; HOMA-S, homeostasis model assessment of insulin sensitivity.</p

Characteristics of the cases and controls in the children and adult populations.

<p>Data are means ± s.d. or medians (interquantile range). HOMA-B, homeostasis model assessment of beta-cell function; HOMA-S, homeostasis model assessment of insulin sensitivity.</p

Glucose homeostasis parameters in nondiabetic children and adult populations according to <i>PCSK1</i> rs6235.

<p>Data are means ± s.d. or medians (interquantile range). <i>P_add</i>_-values were calculated by generalized linear regression using an additive model. BMI was adjusted for age and gender. Plasma glucose/insulin levels and HOMA indices were adjusted for age, gender and BMI. HOMA-B, homeostasis model assessment of beta-cell function; HOMA-S, homeostasis model assessment of insulin sensitivity.</p