Empathy for pain task (EPT).

<p><u>Neutral condition results:</u> (A) categorization accuracy in percent; (B) reaction time in seconds of Harmful behavior and (C) average pain rating scores for each question after scenes of the neutral condition. <u>Intentional condition results:</u> (D) average empathy-related judgments scores for each question after scenes of this condition. <i>* expressed significant differences between the DD patient and control sample.</i></p

Networks connectivity matrices.

<p>(A) Averaged correlation matrices for JM, control sample and conditions. Bottom rows shows t-values for test-t between JM and the control group. (B) T-value distributions for JM (red) and the IAC sample (blue).</p

Local Graph Theory Analysis − Interoceptive macro-state.

<p>Columns indicate each ROI from the interoceptive-emotional network, and rows indicate each graph metric. The Y-axis shows raw metric scores, and the X-axis shows the range of thresholds, from 50 to 800, in steps of 50 (excluding extreme values where networks disaggregate). <i>Boxes indicate significant and trend differences between JM and the control sample. Blue shadows represent controls' standard deviation area.</i></p

Global Graph Theory Analysis.

<p>Columns indicate each resting-state condition, and rows indicate each graph metric. The Y-axis shows raw metric scores, and the X-axis shows the range of thresholds, from 50 to 800, in steps of 50 (excluding extreme values where networks disaggregate). <i>Boxes indicate significant and trend differences between JM and the control sample. Blue shadows represent controls</i>' <i>standard deviation area.</i></p

Interpersonal Reactivity Index (IRI).

<p>Subscales raw scores. * indicates significant differences between the DD patient and the control sample.</p

Resting-state networks.

<p>Most-often reported networks in previous research that contain groups of brain regions highly correlated with each other.</p

Heartbeat Detection Task (HBD).

<p>The Accuracy Index can vary between 0 and 1, with higher scores indicating better interoceptive sensitivity. <i>* indicates significant differences between JM and the control sample.</i></p

Cambridge Depersonalization Scale (CDS).

<p>Subscales and Total Raw Scores. Higher scores in the first four subscales represent a higher presence of experiences from each of the DD main symptoms (all significant, except for Emotional Numbing). Frequency and duration refer to all DD symptoms. Total score is a product of the sum of the measures, and its established score cut off is 70. <i>* expressed significant differences between DD patient and control sample.</i></p

Demographic, clinical and neuropsychological assessment.

<p>Demographic, clinical and neuropsychological assessment.</p