Eighteen Years in the Judicial Catbird Seat

My legal career began with the Florida Supreme Court in September of 1938 as the sole law clerk for the court\u27s six justices

Prevalence of Nicotine Delivery Systems by Biological Sex in the Spit for Science Study

Nicotine intake usage trends have changed over recent decades given the wide variety of nicotine delivery systems including cigarettes, vaping, hookah, and snubs/chewables. These trends also vary by demographic factors, such as race/ethnicity, sex, and socioeconomic status (SES). For example, studies in rat populations, as well as humans, have found that females tend to be more dependent on nicotine products and have a more difficult time quitting than male rats and humans (Pogun et al., 2017). Also, race/ethnicity may impact the frequency of nicotine usage in different populations; in that non-white Hispanics were more susceptible to smoking through adolescence with a peak at ages 12 and 16; whereas non-Hispanic Asian Americans were less susceptible to smoking at ages 11 and 15 (El-Toukhy et al., 2016). Certain nicotine delivery methods may be more available or perhaps more socially accepted by certain groups of people. While lower SES is associated with more prevalent cigarette advertisements and usage, individuals with a higher SES were associated with an increased prevalence of e-cigarette advertisements, leading to an increased frequency of e-cigarette usage among adolescents (Simon et al., 2018). This project aims to document rates of nicotine use across different nicotine delivery systems in college students by demographic factors. We use the Spit for Science (S4S) database to investigate prevalence rates and study if they differ by sex, race/ethnicity, or SES. It is hypothesized that higher SES individuals will have an increased frequency of use with nicotine products that are non-cigarette based, non-white Hispanics will have greater frequency with nicotine usage, and females within the study sample will display a higher dependency on nicotine products than males. Preliminary analyses reveal that there are more female participants than males throughout the S4S cohorts collected between 2020 and 2022. Across cohorts, prevalence of all nicotine delivery systems differs in female and male participants across all products. Larger differences in prevalence between females and males are observed for cigarettes, smokeless tobacco, and cigars than for products that have been introduced more recently, such as hookah, vaping, and heat-not-burn products. Further analyses will focus on patterns of use in relation to race/ethnicity and SES. Understanding nicotine usage trends within our sample could pave the way for additional research (i.e., genetic studies) and allow for the development of prevention/intervention models tailored to our sample populations.https://scholarscompass.vcu.edu/uresposters/1436/thumbnail.jp

The Nucleon ``Tensor Charges'' and the Skyrme Model

The lowest moment of the twist-two, chiral-odd parton distribution $h_1(x)$ of the nucleon can be related to the so-called ``tensor charges'' of the nucleon. We consider the tensor charges in the Skyrme model, and find that in the large-$N_c$, SU(3)-symmetric limit, the model predicts that the octet isosinglet tensor charge, $g^8_T$, is of order $1/N_c$ with respect to the octet isovector tensor charge, $g^3_T$. The predicted $F/D$ ratio is then 1/3, in the large-$N_c$ limit. These predictions coincide with the Skyrme model predictions for the octet ${\it axial}$ charges, $g^8_A$ and $g^3_A$. (The prediction $F/D=1/3$ for the axial charges differs from the commonly quoted prediction of 5/9, which is based on an inconsistent treatment of the large-$N_c$ limit.) The model also predicts that the singlet tensor charge, $g^0_T$, is of order $1/N_c$ with respect to $g^3_T$.Comment: 9 single-spaced pages, no figures, MIT-CTP-212

Jet-Like Correlations with Direct-Photon and Neutral-Pion Triggers at √\u3cem\u3e\u3csup\u3eS\u3c/sup\u3e\u3csub\u3eNN\u3c/sub\u3e\u3c/em\u3e = 200 GeV

Azimuthal correlations of charged hadrons with direct-photon (γdir) and neutral-pion (π0) trigger particles are analyzed in central Au+Au and minimum-bias p+p collisions at in the STAR experiment. The charged-hadron per-trigger yields at mid-rapidity from central Au+Au collisions are compared with p+p collisions to quantify the suppression in Au+Au collisions. The suppression of the away-side associated-particle yields per γdir trigger is independent of the transverse momentum of the trigger particle (ptrigT), whereas the suppression is smaller at low transverse momentum of the associated charged hadrons (passocT). Within uncertainty, similar levels of suppression are observed for γdir and π0 triggers as a function of zT (passocT / ptrigT). The results are compared with energy-loss-inspired theoretical model predictions. Our studies support previous conclusions that the lost energy reappears predominantly at low transverse momentum, regardless of the trigger energy

Jet-Hadron Correlations in √\u3csup\u3es\u3c/sup\u3eNN=200 GeV \u3cem\u3ep\u3c/em\u3e+\u3cem\u3ep\u3c/em\u3e and Central Au+Au Collisions

Azimuthal angular correlations of charged hadrons with respect to the axis of a reconstructed (trigger) jet in Au+Au and p+p collisions at √sNN=200  GeV in STAR are presented. The trigger jet population in Au+Au collisions is biased toward jets that have not interacted with the medium, allowing easier matching of jet energies between Au+Au and p+p collisions while enhancing medium effects on the recoil jet. The associated hadron yield of the recoil jet is significantly suppressed at high transverse momentum (passocT) and enhanced at low passocT in 0%–20% central Au+Au collisions compared to p+p collisions, which is indicative of medium-induced parton energy loss in ultrarelativistic heavy-ion collisions

Redeploying β-lactam antibiotics as a novel antivirulence strategy for the treatment of methicillin-resistant <i>Staphylococcus aureus</i> infections

Innovative approaches to the use of existing antibiotics is an important strategy in efforts to address the escalating antimicrobial resistance crisis. We report a new approach to the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections by demonstrating that oxacillin can be used to significantly attenuate the virulence of MRSA despite the pathogen being resistant to this drug. Using mechanistic in vitro assays and in vivo models of invasive pneumonia and sepsis, we show that oxacillin-treated MRSA strains are significantly attenuated in virulence. This effect is based primarily on the oxacillin-dependent repression of the accessory gene regulator quorum-sensing system and altered cell wall architecture, which in turn lead to increased susceptibility to host killing of MRSA. Our data indicate that beta-lactam antibiotics should be included in the treatment regimen as an adjunct antivirulence therapy for patients with MRSA infections. This would represent an important change to current clinical practice for treatment of MRSA infection, with the potential to significantly improve patient outcomes in a safe, cost-effective manner

Observation of Transverse Spin-Dependent Azimuthal Correlations of Charged Pion Pairs in \u3cem\u3ep\u3c/em\u3e\u3csup\u3e↑\u3c/sup\u3e+\u3cem\u3ep\u3c/em\u3e at √\u3cem\u3es\u3c/em\u3e=200 GeV

We report the observation of transverse polarization-dependent azimuthal correlations in charged pion pair production with the STAR experiment in p↑+p collisions at RHIC. These correlations directly probe quark transversity distributions. We measure signals in excess of 5 standard deviations at high transverse momenta, at high pseudorapidities η\u3e0.5, and for pair masses around the mass of the ρ meson. This is the first direct transversity measurement in p+p collisions

Measurements of Dielectron Production in Au + Au Collisions at √\u3cem\u3es\u3csub\u3eNN\u3c/sub\u3e\u3c/em\u3e = 200 GeV from the STAR Experiment

We report on measurements of dielectron (e+e−) production in Au + Au collisions at a center-of-mass energy of 200 GeV per nucleon-nucleon pair using the STAR detector at BNL Relativistic Heavy Ion Collider. Systematic measurements of the dielectron yield as a function of transverse momentum (pT) and collision centrality show an enhancement compared to a cocktail simulation of hadronic sources in the low invariant-mass region (Mee \u3c 1 GeV/c2). This enhancement cannot be reproduced by the ρ-meson vacuum spectral function. In minimumbias collisions, in the invariant-mass range of 0.30–0.76 GeV/c2, integrated over the full pT acceptance, the enhancement factor is 1.76 ± 0.06 (stat.) ± 0.26 (sys.) ± 0.29 (cocktail). The enhancement factor exhibits weak centrality and pT dependence in STAR’s accessible kinematic regions,while the excess yield in this invariant-mass region as a function of the number of participating nucleons follows a power-law shape with a power of 1.44 ± 0.10. Models that assume an in-medium broadening of the ρ-meson spectral function consistently describe the observed excess in these measurements. Additionally, we report on measurements of ω- and φ-meson production through their e+e− decay channel. These measurements show good agreement with Tsallis blast-wave model predictions, as well as, in the case of the φ meson, results through its K+K− decay channel. In the intermediate invariant-mass region (1.1\u3cMee \u3c 3 GeV/c2), we investigate the spectral shapes from different collision centralities. Physics implications for possible in-medium modification of charmed hadron production and other physics sources are discussed

Isolation of Flow and Nonflow Correlations by Two and Four Particle Cumulant Measurements of Azimuthal Harmonics in √Sɴɴ = GeV Au+Au Collisions

A data-driven method was applied to Au+Au collisions at √Sɴɴ = 200 GeV made with the STAR detector at RHIC to isolate pseudorapidity distance Δ η-dependent and Δ η-independent correlations by using two- and four-particle azimuthal cumulant measurements. We identified a Δ η-independent component of the correlation, which is dominated by anisotropic flow and flow fluctuations. It was also found to be independent of η within the measured range of pseudorapidity | η | \u3c 1. In 20-30% central Au+Au collisions, the relative flow fluctuation was found to be 34% ± 2%(stat.) ± 3%(sys.) for particles with transverse momentum pT less than 2 GeV/c. The Δ η-dependent part, attributed to nonflow correlations, is found to be 5% ± 2%(sys.) relative to the flow of the measured second harmonic cumulant at | Δ η | \u3e 0.7

Di-Hadron Correlations with Identified Leading Hadrons in 200 GeV Au + Au and d + Au Collisions at STAR

The STAR Collaborationpresents for the first time two-dimensional di-hadron correlations with identified leading hadrons in 200 GeV central Au+Au and minimum-bias d+Au collisions to explore hadronization mechanisms in the quark gluon plasma. The enhancement of the jet-like yield for leading pions in Au + Au data with respect to the d + Au reference and the absence of such an enhancement for leading non-pions (protons and kaons) are discussed within the context of a quark recombination scenario. The correlated yield at large angles, specifically in the ridge region, is found to be significantly higher for leading non-pions than pions. The consistencies of the constituent quark scaling, azimuthal harmonic model and a mini-jet modification model description of the data are tested, providing further constraints on hadronization