Inadvertent rupture of iridociliary cyst following transscleral Diode laser

Primary iridociliary cysts can induce plateau iris configuration and angle closure glaucoma. We report a patient with bilateral, primary, ring-shaped, solitary iridociliary cysts. The right eye displayed normal intraocular pressure, oppositional iridocorneal angle closure, and healthy optic nerve head. The left eye had advanced chronic angle closure glaucoma. The management strategy varied between eyes and is discussed. This, to the best of our knowledge, is the first report of transscleral Diode laser application in an eye with a large iridociliary cyst

Cupped disc with normal intraocular pressure: The long road to avoid misdiagnosis

We present a series of six patients who had been receiving treatment for normal tension glaucoma (NTG; five patients) or primary open angle glaucoma (one patient). All of them were found to have optic neuropathy secondary to compression of the anterior visual pathway. Even though uncommon, compression of the anterior visual pathway is an important differential diagnosis of NTG. Diagnosis of NTG should be by exclusion. Here the possible causes of misdiagnosis are discussed. We present an approach to distinguish glaucomatous from nonglaucomatous optic neuropathy. The article also emphasizes how important it is for the clinicians to consider the total clinical picture, and not merely the optic disc morphology, to avoid the mismanagement of glaucoma, especially the NTG

A randomized, crossover, open label pilot study to evaluate the efficacy and safety of Xalatan ® in comparison with generic Latanoprost (Latoprost) in subjects with primary open angle glaucoma or ocular hypertension

<b>Aim: </b> To compare the efficacy and tolerability of Xalatan &#x00AE; with generic latanoprost (Latoprost) in subjects with primary open angle glaucoma (POAG) or ocular hypertension (OH). <b> Materials and Methods:</b> This was a single-center, randomized, open label, crossover, two period comparative study. At the baseline visit, subjects were randomized to two groups. Group A received Xalatan &#x00AE; for weeks 1-12 followed by Latoprost for weeks 13-24. Group B received Latoprost for weeks 1-12 followed by Xalatan &#x00AE; for weeks 13-24. <b> Results:</b> 30 subjects were recruited, 12 in Group A and 18 in Group B. In subjects administered Xalatan &#x00AE;, intraocular pressure (IOP) showed a greater decrease (<i> P</i> &#60; 0.001) from 23.64 &#x00B1; 3.13 mmHg at baseline to 14.29 &#x00B1; 1.61 mmHg at week 12 (fall of 9.35 &#x00B1; 3.55 mmHg, 38.66&#x0025; &#x00B1; 10.29) than that seen in the Latoprost group (22.74 &#x00B1; 2.47 mmHg to 16.98 &#x00B1; 2.49 mmHg, fall of 5.76 &#x00B1; 1.41 mmHg; 25.42&#x0025; &#x00B1; 5.98). In period 2 when subjects were crossed over to Xalatan &#x00AE; from Latoprost, there was a further fall from 16.98 &#x00B1; 2.49 mmHg to 16.09 &#x00B1; 1.49 at week 24 (fall of 0.89 &#x00B1; 1.59 mmHg; 4.3&#x0025; &#x00B1; 8.76). However, when subjects were crossed over to Latoprost from Xalatan &#x00AE;, the IOP rose from 14.29 &#x00B1; 1.61 mmHg to 15.36 &#x00B1; 1.71 mmHg at week 24 (8.86&#x0025; &#x00B1; 17.76). There was no significant difference in incidence of conjunctival hyperemia or any other adverse events in both the groups. <b> Conclusion:</b> The magnitude of IOP lowering in patients with POAG and OH with Xalatan &#x00AE; and Latoprost is different. In our study, the IOP lowering with Xalatan &#x00AE; was higher than that with Latoprost

Construction and validation of logMAR visual acuity charts in seven Indian languages

Purpose: The evaluation of visual impairment requires the measurement of visual acuity with a validated and standard logMAR visual acuity chart. We aimed to construct and validate new logMAR visual acuity chart in Indian languages (Hindi, Bengali, Telugu, Urdu, Kannada, Malayalam, and Assamese). Methods: The commonly used font in each language was chosen as the reference and designed to fit the 5 × 5 grid (Adobe Photoshop). Ten letters (easiest to difficult) around median legibility score calculated for each language based on the results of legibility experiment and differing by 10% were selected. The chart was constructed based on the standard recommendations. The repeatability of charts was tested and also compared with a standard English Early Treatment Diabetic Retinopathy Study (ETDRS) logMAR chart for validation. Results: A total of 14 rows (1.0 to -0.3 logMAR) with five letters in each line were designed with the range of row legibility between 4.7 and 5.3 for all the language charts. Each chart showed good repeatability, and a maximum difference of four letters was noted. The median difference in visual acuity was 0.16 logMAR for Urdu and Assamese chart compared to ETDRS English chart. Hindi and Malayalam chart had a median difference of 0.12 logMAR. When compared to the English chart a median difference of 0.14 logMAR was noted in Telugu, Kannada, and Bengali chart. Conclusion: The newly developed Indian language visual acuity charts are designed based on the standard recommendations and will help to assess visual impairment in people of these languages across the country

Boston keratoprosthesis and Ahmed glaucoma valve for visual rehabilitation in congenital anterior staphyloma

Congenital anterior staphyloma entails grave visual prognosis. The majority of reported patients have undergone enucleation. We report a promising result of staphylectomy with implantation of a keratoprosthesis and a glaucoma drainage device in a seven-month-old child with a large, congenital anterior staphyloma