The eccentricity in heavy-ion collisions from Color Glass Condensate initial conditions

The eccentricity in coordinate-space at midrapidity of the overlap zone in high-energy heavy-ion collisions predicted by the $k_\perp$-factorization formalism is generically larger than expected from scaling with the number of participants. We provide a simple qualitative explanation of the effect which shows that it is not caused predominantly by edge effects. We also show that it is quite insensitive to ``details'' of the unintegrated gluon distribution functions such as the presence of leading-twist shadowing and of an extended geometric scaling window. The larger eccentricity increases the azimuthal asymmetry of high transverse momentum particles. Finally, we point out that the longitudinal structure of the Color Glass Condensate initial condition for hydrodynamics away from midrapidity is non-trivial but requires understanding of large-$x$ effects.Comment: 8 pages, 7 figures; v3: added note regarding Qs2~n_part versus Qs2~T_A, final version to appear in PR

Inequalities for α-fractional differentiable functions

Abstract In this article, we present an identity and several Hermite-Hadamard type inequalities for conformable fractional integrals. As applications, we establish some inequalities for certain special means of two positive real numbers and give the error estimations for the trapezoidal formula

Design of an Intelligent Traffic Light Control System

Today, the number of cars is rapidly increasing which creates a real traffic control problem. While the conventional traffic control systems are inconvenient to provide fast and fair solutions for the congestion problem. This research addresses the traffic control problem and hence proposes an intelligent traffic light control system. In particular, the proposed system senses the presence or absence of cars on each lane, and then estimates the time to open each lane, which is proportional to the number of cars on that lane. Practically, the system circuit has been printed on a board with three main components; namely pressure sensors, microcontroller, and traffic lights. Then a C program has been developed to enable the microcontroller for receiving inputs from sensors, calculating the times to open lanes and sending appropriate logic decisions to traffic light. The obtained results prove the accuracy and reliability of the system.    In addition to the practical test, the intelligent traffic light control system has been successfully simulated, where the simulation results are found to be the same as the calculated ones

Boundary condition at the junction

The quantum graph plays the role of a solvable model for a two-dimensional network. Here fitting parameters of the quantum graph for modelling the junction is discussed, using previous results of the second author.Comment: Replaces unpublished draft on related researc

Hematoma Enlargement Among Patients with Traumatic Brain Injury: Analysis of a Prospective Multicenter Clinical Trial

Observational studies suggest that hematomas continue to enlarge during hospitalization in patients with traumatic brain injury (TBI). There is limited data regarding factors associated with hematoma enlargement and on whether hematoma enlargement contributes directly to death and disability in patients with TBI. We analyzed data collected as part of the Resuscitation Outcomes Consortium Hypertonic Saline and TBI Study. Hematoma enlargement was ascertained and collected as a predefined safety endpoint. We evaluated the effect of hematoma enlargement on the risk of death and disability at 6 months based on the Extended Glasgow Outcome Scale (GOSE) (dichotomized as \u3e4 or ≤4) using stepwise logistic regression analysis. We adjusted for age (continuous variable), admission GCS score (dichotomized at \u3e5 and ≤5), and computed tomography (CT) scan classification (Marshall grades entered as a categorical variable). Of the 1200 patients with severe TBI analyzed, 238 (19.8%) patients were reported to have hematoma enlargement as an adverse event. The proportion of patients who reached favorable outcome at 6 months was significantly lower (defined by GOSE of \u3e4) among patients with hematoma enlargement (29.0% vs. 40.1%, p\u3c.0001). The proportion of patients who died within 6 months was significantly higher among patients with hematoma enlargement (31.9% vs. 20.7%, p\u3c.0001). After adjusting for age, admission GCS score, and initial injury score, the odds of favorable outcome was lower in patients with hematoma enlargement (odds ratio 0.7, 95% confidence interval [CI]; 0.5–0.97). Our results suggest that hematoma enlargement may be a direct contributor to death and disability in patients with TBI at 6 months. Future clinical trials must continue to evaluate new therapeutic interventions aimed at reducing hematoma enlargement with a favorable risk benefit ratio in patients with TBI

Conserved Quantities in f(R)f(R) Gravity via Noether Symmetry

This paper is devoted to investigate $f(R)$ gravity using Noether symmetry approach. For this purpose, we consider Friedmann Robertson-Walker (FRW) universe and spherically symmetric spacetimes. The Noether symmetry generators are evaluated for some specific choice of $f(R)$ models in the presence of gauge term. Further, we calculate the corresponding conserved quantities in each case. Moreover, the importance and stability criteria of these models are discussed.Comment: 14 pages, accepted for publication in Chin. Phys. Let

Effects of Bacillus subtilis on performance, immune system and gut in Salmonella-challenged broilers

The goal of this study was to compare the effects of Bacillus subtilis and the antibiotic enrofloxacin on growth performance, immune response, intestinal histomorphometry and cecal Salmonella numbers in broilers challenged with S. gallinarum. Salmonella-free chicks (n = 240) were allocated to four groups, comprising six replicates (n = 10) each. Group NN was not infected and received no treatment. Group SN was infected with Salmonella and received no treatment. Group SE was infected with Salmonella and treated with the antibiotic enrofloxacin. Group SP was infected with Salmonella and treated orally with the probiotic B. subtilis. Initially the groups that were infected with Salmonella had reduced growth performance compared with NN. By the fourth week, SE and SP had recovered and weighed as much as or more than NN. The SP group had greater cellular immunity and relative weights of the bursa and thymus than the other groups. SN had the lowest villus height in all the segments of the small intestine and a larger Salmonella population in the ceca. Probiotic supplementation reduced the pathological outcomes more than enrofloxacin. Prophylactic use of B. subtilis-type probiotics had similar effects to the use of antibiotics, alleviated the stress related to infection of S. gallinarum, and improved the growth performance, immune function, and gut mucosal development in broilers. Keywords: growth promoters, immunity, probiotics, poultry villi lengt

TAT-peptide conjugated repurposing drug against SARS-CoV-2 main protease (3CLpro): potential therapeutic intervention to combat COVID-19

The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that originated in Chinese city of Wuhan has caused around 906,092 deaths and 28,040,853 confirmed cases worldwide (WHO, 11 September, 2020). In a life-threatening situation, where there is no specific and licensed anti-COVID-19 vaccine or medicine available; the repurposed drug might act as a silver bullet. Currently, more than 211 vaccines, 80 antibodies, 31 antiviral drugs, 35 cell-based, 6 RNA-based and 131 other drugs are in clinical trials. It is therefore utter need of the hour to develop an effective drug that can be used for the treatment of COVID-19 before a vaccine can be developed. One of the best-characterized and attractive drug targets among coronaviruses is the main protease (3CL^{pro}). Therefore, the current study focuses on the molecular docking analysis of TAT-peptide^{47–57} (GRKKRRQRRRP)-conjugated repurposed drugs (i.e., lopinavir, ritonavir, favipiravir, and hydroxychloroquine) with SARS-CoV-2 main protease (3CL^{pro} to discover potential efficacy of TAT-peptide (TP) - conjugated repurposing drugs against SARS-CoV-2. The molecular docking results validated that TP-conjugated ritonavir, lopinavir, favipiravir, and hydroxychloroquine have superior and significantly enhanced interactions with the target SARS-CoV-2 main protease. In-silico approach employed in this study suggests that the combination of the drug with TP is an excelling alternative to develop a novel drug for the treatment of SARS-CoV-2 infected patients. The development of TP based delivery of repurposing drugs might be an excellent approach to enhance the efficacy of the existing drugs for the treatment of COVID-19. The predictions from the results obtained provide invaluable information that can be utilized for the choice of candidate drugs for in vitro, in vivo and clinical trials. The outcome from this work prove crucial for exploring and developing novel cost-effective and biocompatible TP conjugated anti-SARS-CoV-2 therapeutic agents in immediate future

High pT hadron spectra at RHIC: an overview

Recent results on high transverse momentum (pT) hadron production in p+p, d+Au and Au+Au collisions at the Relativistic Heavy Ion Collider (RHIC) are reviewed. Comparison of the nuclear modification factors, $R_{dAu}(pT)$ and $R_{AA}(pT)$, demonstrates that the large suppression in central Au+Au collisions is due to strong final-state effects. Theoretical models which incorporate jet quenching via gluon Bremsstrahlung in the dense partonic medium that is expected in central Au+Au collisions at ultra-relativistic energies are shown to reproduce the shape and magnitude of the observed suppression over the range of collision energies so far studied at RHIC.Comment: 12 pages, 10 figures, Talk given at Hot Quarks 2004: Workshop for Young Scientists on the Physics of Ultrarelativistic Nucleus-Nucleus Collisions (HQ'04), Taos Valley, New Mexico, 18-24 Jul 2004, to be published in J. Phys.