Occurrence of multi-drug resistant tuberculosis among patients with suspected tuberculosis in Katsina State north western Nigeria

Background: A couple of decades ago, experts in the study of Tuberculosis excogitated that multi drug resistant Tuberculosis (MDR-TB) is uncommon in sub-Saharan Africa due to the delayed introduction of rifamycin based regimens. However, previous studies showed that 21% of the global MDR-TB burden occurs in the region; with South Africa, Nigeria and Ethiopia ranking first second and third, respectively. Aims and objectives: the objective of this study is to determine the prevalence of drug resistant tuberculosis in patients suspected of having tuberculosis. The aims are: to determine the prevalence of MDR-TB in the non HIV patients presenting with persistent cough, to determine the prevalence of MDR-TB in HIV infected patients and to appraise the extent of the association between MDR-TB and HIV in this region. Methods: Eight hundred and twenty four (824) sputa were collected from suspected participants and analyzed for the presence Mycobacterium tuberculosis and rifampicin resistant strains using a nucleic acid amplification test based machine, Gene expert (Cepheid inc. USA). Results: One hundred and seventy three (21.0%) of the 824 had MTB and 13(7.5%) of the MTB cases were MDR-TB. Conclusion: There is a high prevalence of MDR-TB among patients with chronic cough in the region and it is found in both HIV positive and negative patients

Recent Advances in Solar Drying of Agricultural Produce in Nigeria: NSPRI Experience

Agricultural products are dried to enhance storage stability, in order to reduce post harvest losses, minimize packaging requirement and reduce transport weight. Crop drying through the sun is the most common practice in the country due to its no energy cost but often result in poor quality, unhygienic and contaminated products. This has been a major threat to food safety. Energy consumption and quality of dried products are critical parameters in the selection of drying process. An optimum drying system for the preparation of quality dehydrated products is supposed to be cost effective with less drying time and damage to the product. To reduce the energy utilization and operational cost as well to further produce high quality safe products, new trends in solar drying system were developed by the Nigerian Stored Products Research Institute (NSPRI) in order to proffer solutions to the threat in food safety as well as farmers and processors quest for drying with minimal energy cost.  The technologies include mobile solar tent dryers, green house solar tent dryers and parabolic solar tent dryers. These entire dryers have great scope for the production of quality dried products and powders. These advancements have taken the advantage of material selection, design calculations to improve on the technology in order to achieve quality output in terms of environmental parameters and product quality. The advancement has also taken care of times of low solar irradiance especially during the rainy season which is highly humid. The temperature range obtained from the mobile, green house and parabolic solar dryers are 20 – 59.5°C, 21.5 - 68°C, and 25-78°C respectively while their respective  average relative humidity are 71.64%, 60.21%, 49.77%. The ambient temperature range and relative humidity are 20 – 42.5°C and 74.88%. Experimental studies on the performance of the varied solar tent dryers were conducted using Chilli Pepper, Yam, Meat, Fish, Vegetables and plantain have been carried out the Beef meat, Chilli pepper and Telefeiria occidentalis vegetable were dried in the mobile solar tent dryer, greenhouse  solar dryer and parabolic solar dryer. The beef of 71.243% initial moisture content was dried to 12.15%, 12.01% and 10.09% in the aforementioned respective dryers within a period of 5 days. Also the chilli pepper of 89.40% initial moisture content was dried to 12%, 11.3% and 9.3% moisture content respectively in the dryers within a period of 8 days; while the Telefairia occidentalis vegetable of 11.0% initial moisture content was dried within a period of 5 hours to 6.0%, 5.5% and 4.0% moisture content

Seroprevalence of Influenza A Virus in Dromedaries in North-Western Nigeria

Although influenza A virus is endemic in wild waterfowl, domestic poultry, swine, humans, bats, cetaceans, dogs, and horses, there is a paucity of data on the potential role of camels in zoonotic transmission of the virus. To estimate the seroprevalence of the influenza A virus in camel populations, four local government areas of Nigeria that share an international border with the Niger Republic were selected. Blood samples from 184 one-hump camels (dromedaries) were collected and tested for influenza IgG antigen by ELISA. Each camel’s demographic variable, such as age, gender, location, production system, and usage, was recorded. The overall seroprevalence rate of influenza virus IgG in this study was 10.33% (95%CI: 6.33–15.66%). In the bivariate model, there was no significant difference in gender, age, site location and production system, except for usage. There was a significantly lower seroprevalence rate among camels used for labour (odds ratio (OR) = 0.34, 95% CI: 0.10–0.97) than those used for meat consumption; however, not after adjusting for other variables in the model. Increase surveillance through early detection, prediction, and risk assessment of pathogens in animal reservoirs and environmental contamination as One Health strategies to reduce potential human spillover is recommended. Molecular epidemiology studies could better elucidate the role of camels in the dynamics of disease transmission pathways

Large Mammals and Wetland utilization: a case study in Yankari Game Reserve Nigeria

The African plain harbours high abundance and diversity of mammals, most of which are confined to protected areas (PAs) due to anthro‐ pogenic threats (Craigie et al., 2010; Dirzo et al., 2014; Estes, 1999; Kingdon, 1997). Also, PAs face problems of hunting, logging and live‐ stock grazing, conflict of interest and poor management (Caro, 2001; Dharmaratne, Sang, &Walling, 2000; Gardner et al., 2009; Geldmann et al., 2015; Geldmann et al., 2015; Hall, Harris, Medjibe, & Ashton, 2003; Pressey, 1994; Salum, Eustace, Malata, & Mbangwa, 2017; Thuiller, 2007), consequently disrupting conservation goals, effective monitor‐ ing and understanding of habitat utilisation dynamics of mammals. Although wetlands are important habitats for sustaining animal populations, there is a widespread trend of increasing degradation of these habitats (Fynn, Chase, & Rӧder, 2014) and dearth of infor‐ mation pertaining to wetland utilisation in most PAs. While this is integral for effective conservation practice, few studies focus on this area in Africa (Arzamendia, Cassini, & Vila, 2006; Kumar, Mudappa, & Raman, 2010; Rahman et al., 2017). Here, we investigated the wet‐ land utilisation dynamics of large mammals in Yankari Game Reserve (YGR). The objective was to determine abundance, density and di‐ versity of large mammals and whether these variables were associ‐ ated with wetland size and time of da

Talent management practices on employee performance: a mediating role of employee engagement in institution of higher learning: quantitative analysis

Purpose: The purpose of this paper is to investigate the effect of talent management (TM) practices on employee performance (EP) and to explore the mediating role of employee engagement (EE) on the relationship between TM practices and EP in Malaysian private universities (MPUs). Design/methodology/approach: The paper used both descriptive and quantitative approaches, and the unit of analysis of this research consists of MPUs academic staff. The research sample consists of 314 MPUs academic staff, and a questionnaire was used to collect data from the target respondents, while partial least squares-structural equation modelling was used to evaluate the study hypotheses through bootstrapping approach. Findings: The research outcome revealed that TM practices that comprise of talent recruitment practice (TRP), training and development practice (T&DP), compensation practice (CP) have a significant effect on EP. Furthermore, EE partially mediates the relationship between T&DP, CP and EP, while EE does not mediate the relationship between TRP and EP in MPUs. Practical implications: The research suggests that universities management should focus on TM practices as a tool to achieve and maintain EE and positive attitudes (EP) in relation to work. Originality/value: The research makes substantial contributions to the literature by investigating the effect of TM practices on EP through the role of EE as mediation in MPUs. The research is one of the very few studies undertaken in MPUs. Therefore, the results of this research serve as a guide for the universities management to develop their institutional strategies and policies in a manner in which their employees’ success can be achieved and encouraged.International Journal of Business and Society

Effect of Temperature on Drying Characteristics and Quality of Three Nigerian Onion Varieties Using a Fabricated Electrically Powered Dryer

The research work is done to evaluate the effect of temperature on drying characteristics and quality of red, cream and white varieties Nigerian onion using a locally fabricated electrically powered dryer. Clean onion samples of 1.5 kg from each of the three varieties were sliced into 3 mm thickness. Fresh samples of the three onion varieties were analyzed to determine the initial values of protein, fat, ash, crude fibre, and moisture content on a dried basis (m.c.d.b.) using recommended AOAC methods.. Vitamin C and microbial loads content were determined before loading into a locally fabricated electrically-powered dryer. The onion samples were dried at varying pre-determined temperatures of 50, 60, and 70 oC. After drying, the proximate compositions, vitamin C and microbial loads were also determined. The protein, fat, ash and crude fibre of the fresh onion samples were 1.5, 0.5, 0.6 and 0.5%, respectively, while m.c.d.b, vitamin C content and microbial loads ranged from 85.1-88.2%, 8.1-8.3 mg/100 gm and 4.45-5.39 mg. Red onion samples were dried for 13:15h, 12:10h and 10:30h; white onion samples for 13:00h, 12:25h and 10:40h; while cream onion samples for 13:10h, 12:35h and 10:15h at 50, 60, and 70 oC, respectively. The protein, fat, ash, crude fibre, m.c.d.b, vitamin C content and microbial loads of the dried onion samples at all the drying temperatures ranged from 10.110.4, 1.1-1.5, 3.3-3.5, 5.5-5.8, 5.5-6.9%, 3.1-4.9 mg/100 gm, 1.314.17 mg, respectively. The drying temperature had a significant effect (p-value < 0.05) on the quality of all the onion samples. At 70 oC, protein, fibre, ash, fat and pungency retention were significantly (p< 0.05) high and within acceptable limits while microbial loads were low with the reduction in Vitamin C contents in all the onion varieties. Therefore, onion can best be dried at 70 oC to achieve the optimum quality and flavour required for its use as a spice

Tuberculosis of the Breast: An Initial Presentation of the Metabolic Syndrome with Type 2 Diabetes Mellitus in a Young Nigerian Woman

Breast tuberculosis is an uncommon presentation of extra pulmonary tuberculosis. A 40-year-old obese woman presented with a right breast abscess which had failed to heal after surgical drainage. There was no family history of breast disease. Biopsy and histology of the lesion showed chronic granulomatous inflammation with positive stains for acid fast bacilli compatible with tuberculosis. Further evaluation confirmed metabolic syndrome with type 2 diabetes mellitus. She was placed on antituberculosis chemotherapy and appropriate therapy for diabetes mellitus with complete resolution of the lesion. We report this case because of its rarity and to highlight the association between tuberculosis an infectious disease and overnutrition in diabetes mellitus, a noncommunicable disease

Early infant diagnosis of HIV infection at the John F. Kennedy Medical Center, Monrovia, Liberia

Background: Vertical transmission accounts for majority of new HIV infections among children worldwide. Ninety percent of HIV-positive children reside in Sub- Saharan Africa with their infection predominantly acquired via vertical transmission. In 2004, the vertical transmission rate of HIV in Africa was estimated at 25 − 40% but, remarkably, the rate has significantly decreased to less than 5% in most African countries following implementation and expansion of prevention of MTCT (PMTCT) programs. Objective: To determine the rate of and factors associated with vertical transmission of HIV among attendees of early infant diagnosis (EID) program of an academic and community-based tertiary facility in Liberia. Design: A retrospective cross-sectional analysis. Methods: A retrospective review of medical records of babies seen at Pediatric Unit of Infectious Disease Clinic of John F Kennedy Medical Center (JFKMC) in Monrovia, Liberia between January 1, 2016 and December 31, 2020. All subjects were children born to HIV-positive mothers and who had HIV DNA PCR testing performed between the ages of 6 weeks and 6 months. Children who suffered early neonatal death and those who did not undergo PCR testing were excluded. Demographics of mother to child pairs as well as factors known to influence vertical transmission of HIV such as partial (15.8%) or full (84.2%) participation in prevention of MTCT (PMTCT) programs, mode of delivery, breastfeeding and utilization of post-exposure prophylaxis were collected and assessed. Binomial logistic regression analyses were used to assess factors associated with vertical transmission. Results: During the study timeframe, 284 children had a HIV DNA PCR test with a male:female ratio − 1.3:1. Sixteen tested positive (conducted at a mean of 155 days post birth) giving a vertical transmission rate of 5.6%. For 239 mothers (84.2%) who had full PMTCT, 1.3% of their children tested positive, while for 45 mothers (15.8%) who had partial PMTCT, 28.8% of their children being positive. Two hundred and seventy six children (97%) had exclusive breastfeeding, 13 of whom tested positive while 2 children who were mixed fed tested positive. Children who had Nevirapine vs no prophylaxis (OR = 1.89[95% CI 1.16 − 2.96]), were delivered via caesarian section vs vaginal delivery (OR= 2.26[95% CI 1.92 − 4.12].) and full versus partial participation in PMTCT programs (OR = 4.02[95% CI 2.06 − 4.13] were more likely to have negative HIV test. Conclusion: Vertical transmission rate was found to be high in Liberia and may be driven by suboptimal PMTCT program participation including post-exposure prophylaxis for infants. Therefore, strategies to scale up and improve uptake of PMTCT services are needed to mitigate the burden of HIV among children