Obstetric outcomes of sars-cov-2 infection in asymptomatic pregnant women

Altres ajuts: Fondo Europeo de Desarrollo Regional (FEDER)Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if SARS-CoV-2 infection at delivery among asymptomatic mothers had different obstetric outcomes compared to negative patients. This was a multicenter prospective study based on universal antenatal screening for SARS-CoV-2 infection. A total of 42 hospitals tested women admitted for delivery using polymerase chain reaction, from March to May 2020. We included positive mothers and a sample of negative mothers asymptomatic throughout the antenatal period, with 6-week postpartum follow-up. Association between SARS-CoV-2 and obstetric outcomes was evaluated by multivariate logistic regression analyses. In total, 174 asymptomatic SARS-CoV-2 positive pregnancies were compared with 430 asymptomatic negative pregnancies. No differences were observed between both groups in key maternal and neonatal outcomes at delivery and follow-up, with the exception of prelabor rupture of membranes at term (adjusted odds ratio 1.88, 95% confidence interval 1.13-3.11; p = 0.015). Asymptomatic SARS-CoV-2 positive mothers have higher odds of prelabor rupture of membranes at term, without an increase in perinatal complications, compared to negative mothers. Pregnant women testing positive for SARS-CoV-2 at admission for delivery should be reassured by their healthcare workers in the absence of symptoms

The association between SARS-CoV-2 infection and preterm delivery: a prospective study with a multivariable analysis.

To determine whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, the cause of COVID-19 disease) exposure in pregnancy, compared to non-exposure, is associated with infection-related obstetric morbidity. We conducted a multicentre prospective study in pregnancy based on a universal antenatal screening program for SARS-CoV-2 infection. Throughout Spain 45 hospitals tested all women at admission on delivery ward using polymerase-chain-reaction (PCR) for COVID-19 since late March 2020. The cohort of positive mothers and the concurrent sample of negative mothers was followed up until 6-weeks post-partum. Multivariable logistic regression analysis, adjusting for known confounding variables, determined the adjusted odds ratio (aOR) with 95% confidence intervals (95% CI) of the association of SARS-CoV-2 infection and obstetric outcomes. Preterm delivery (primary), premature rupture of membranes and neonatal intensive care unit admissions. Among 1009 screened pregnancies, 246 were SARS-CoV-2 positive. Compared to negative mothers (763 cases), SARS-CoV-2 infection increased the odds of preterm birth (34 vs 51, 13.8% vs 6.7%, aOR 2.12, 95% CI 1.32-3.36, p = 0.002); iatrogenic preterm delivery was more frequent in infected women (4.9% vs 1.3%, p = 0.001), while the occurrence of spontaneous preterm deliveries was statistically similar (6.1% vs 4.7%). An increased risk of premature rupture of membranes at term (39 vs 75, 15.8% vs 9.8%, aOR 1.70, 95% CI 1.11-2.57, p = 0.013) and neonatal intensive care unit admissions (23 vs 18, 9.3% vs 2.4%, aOR 4.62, 95% CI 2.43-8.94, p  This prospective multicentre study demonstrated that pregnant women infected with SARS-CoV-2 have more infection-related obstetric morbidity. This hypothesis merits evaluation of a causal association in further research

Seminario Hegel Complutense 2023-2024. Lectura de "Líneas fundamentales de la filosofía del derecho"

Este proyecto Innova-Docencia pretende consolidar la actividad del Seminario Hegel Complutense para contribuir a la mejora de la calidad de la enseñanza y el aprendizaje universitarios de la filosofía. El proyecto cuenta con 26 docentes provenientes de dos facultades de la UCM (Filosofía y Filología), ocho universidades nacionales (UAM, UNED, UC3M, IE, UFV, UV, UNED, UB) y siete extranjeras de Chile, Holanda, Italia y Macedonia del Norte (UC, PUCV, ISSHS, UniFi, UDP, RUG, UniMi), así como con estudiantes de Grado, Máster y Doctorado de varias facultades de la UCM (Filosofía, Filología, Bellas Artes, Derecho e Historia) y profesores de IES de la Comunidad de Madrid. El seminario nace en junio de 2022 a petición de un grupo de estudiantes de Grado y Máster a la investigadora principal de este proyecto dada la saturación, la fragmentación y los tiempos en ocasiones limitados de los planes de estudios oficiales. El presente proyecto pretende consolidar el Seminario Hegel Complutense para el curso 2023-2024 y siguientes, ofreciendo este curso una lectura de la obra de Hegel Líneas fundamentales de la filosofía del derecho, con la vocación de fundar un punto de encuentro y colaboración entre estudiantes, investigadores y docentes, fortaleciendo competencias relacionadas con el aprendizaje y la investigación, difundiendo sus resultados en colaboración con otros espacios de investigación y/o transferencia del conocimiento y complementando los contenidos de los planes de estudio oficiales (Grado, dobles Grados, Master y Doctorado). La naturaleza participativa del seminario con lectura por grupos y la discusión colectiva ofrece la oportunidad de ensayar metodologías novedosas y enfocadas al alumno. El seminario se enfoca al trabajo con nuevas herramientas digitales y elaboración de materiales en vídeo.Depto. de Filosofía y SociedadDepto. de Lógica y Filosofía TeóricaFac. de FilosofíaFac. de FilologíaFac. de DerechoFac. de Geografía e HistoriaFALSEsubmitte