A New Z=0 Metagalactic Ultraviolet Background Limit

We present new integral-field spectroscopy in the outskirts of two nearby, edge-on, late-type galaxies to search for the H alpha emission that is expected from the exposure of their hydrogen gas to the metagalactic ultraviolet background (UVB). Despite the sensitivity of the VIRUS-P spectrograph on the McDonald 2.7 m telescope to low surface brightness emission and the large field of view, we do not detect H alpha to 5 sigma upper limits of 6.4 x 10(-19) erg s(-1) cm(-2) arcsec(-2) in UGC 7321 and of 25 x 10(-19) erg s(-1) cm(-2) arcsec(-2) in UGC 1281 in each of the hundreds of independent spatial elements (fibers). We fit gas distribution models from overlapping 21 cm data of HI, extrapolate one scale length beyond the HI data, and estimate predicted H alpha surface brightness maps. We analyze three types of limits from the data with stacks formed from increasingly large spatial regions and compare to the model predictions: (1) single fibers, (2) convolution of the fiber grid with a Gaussian, circular kernel (10('') full width at half-maximum), and (3) the co-added spectra from a few hundred fibers over the brightest model regions. None of these methods produce a significant detection (>5 sigma) with the most stringent constraints on the Hi photoionization rate of Gamma(z = 0) < 1.7 x 10(-14) s(-1) in UGC 7321 and Gamma(z = 0) < 14 x 10(-14) s(-1) in UGC 1281. The UGC 7321 limit is below previous measurement limits and also below current theoretical models. Restricting the analysis to the fibers bound by the HI data leads to a comparable limit; the limit is Gamma(z = 0) < 2.3 x 10(-14) s(-1) in UGC 7321. We discuss how a low Lyman limit escape fraction in z similar to 0 redshift star-forming galaxies might explain this lower than predicted UVB strength and the prospects of deeper data to make a direct detection.U.S. Government NAG W-2166National Science FoundationUT David BrutonTexas Norman Hackerman Advanced Research Program 003658-0295-2007Cynthia and George Mitchell FoundationMcDonald Observator

A pilot study of homeworking: WorkHouse (30)

Workhouse aims to improve technology-based homeworking, through an understanding of working patterns, interactions with architecture and furniture. A log record of participants working environments, their hours of work, and their posture. The 10 participants revealed a range of working patterns (6:30 to midnight); choice of rooms, even with a dedicated study available. There are some issues to be resolved with the logs: recording of working hours, posture, and the need to make further decisions about the data required

Tying the loose ends together in DNA double strand break repair with 53BP1

To maintain genomic stability and ensure the fidelity of chromosomal transmission, cells respond to various forms of genotoxic stress, including DNA double-stranded breaks (DSBs), through the activation of DNA damage response signaling networks. In response to DSBs as induced by ionizing radiation (IR), during DNA replication, or through immunoglobulin heavy chain (IgH) rearrangements in B cells of lymphoid origin, the phosphatidyl inositol-like kinase (PIK) kinases ATM (mutated in ataxia telangiectasia), ATR (ATM and Rad3-related kinase), and the DNA-dependent protein kinase (DNA-PK) activate signaling pathways that lead to DSB repair. DSBs are repaired by either of two major, non-mutually exclusive pathways: homologous recombination (HR) that utilizes an undamaged sister chromatid template (or homologous chromosome) and non- homologous end joining (NHEJ), an error prone mechanism that processes and joins broken DNA ends through the coordinated effort of a small set of ubiquitous factors (DNA-PKcs, Ku70, Ku80, artemis, Xrcc4/DNA lig IV, and XLF/Cernunnos). The PIK kinases phosphorylate a variety of effector substrates that propagate the DNA damage signal, ultimately resulting in various biological outputs that influence cell cycle arrest, transcription, DNA repair, and apoptosis. A variety of data has revealed a critical role for p53-binding protein 1 (53BP1) in the cellular response to DSBs including various aspects of p53 function. Importantly, 53BP1 plays a major role in suppressing translocations, particularly in B and T cells. This report will review past experiments and current knowledge regarding the role of 53BP1 in the DNA damage response

B2 0902+34: A Collapsing Protogiant Elliptical Galaxy at z=3.4

We have used the visible integral-field replicable unit spectrograph prototype (VIRUS-P), a new integral field spectrograph, to study the spatially and spectrally resolved Lyman-alpha emission line structure in the radio galaxy B2 0902+34 at z=3.4. We observe a halo of Lyman-alpha emission with a velocity dispersion of 250 km/s extending to a radius of 50 kpc. A second feature is revealed in a spatially resolved region where the line profile shows blueshifted structure. This may be viewed as either HI absorption at -450 km/s or secondary emission at -900 km/s from the primary peak. Our new data, in combination with the 21 cm absorption, suggest two important and unexplained discrepancies. First, nowhere in the line profiles of the Lyman-alpha halo is the 21 cm absorber population evident. Second, the 21 cm absorption redshift is higher than the Lyman-alpha emission redshift. In an effort to explain these two traits, we have undertaken the first three dimensional Monte Carlo simulations of resonant scattering in radio galaxies. Though simple, the model produces the features in the Lyman-alpha data and predicts the 21 cm properties. To reach agreement between this model and the data, global infall of the HI is strictly necessary. The amount of gas necessary to match the model and data is surprisingly high, >= 10E12 solar masses, an order of magnitude larger than the stellar mass. The collapsing structure and large gas mass lead us to interpret B2 0902+34 as a protogiant elliptical galaxy.Comment: 30 pages, 8 figures, 4 tables, accepted in Ap

How EcoDesign methodologies can be leveraged to reduce the carbon footprint throughout a product lifecycle

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Minimum Information about a Neuroscience Investigation (MINI) Electrophysiology

This module represents the formalized opinion of the authors and the CARMEN consortium, which identifies the minimum information required to report the use of electrophysiology in a neuroscience study, for submission to the CARMEN system (www.carmen.org.uk).&#xd;&#xa