1,303 research outputs found

    Technology Transfer through Imports

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    While there is general agreement that technology differences must figure prominently in any successful account of the cross-country income variation, not much is known on the source of these technology differences. This paper examines cross-country income differences in terms of factor accumulation, domestic R&D, and foreign technological spillovers. The empirical analysis encompasses seventeen industrialized countries in four continents over three decades, at a level disaggregated enough to identify innovations in a number of key high-tech sectors. International technology transfer is found to play a crucial part in accounting for income differences. We also relate technology transfer to imports, showing that imports are often a major channel. At the same time, our analysis highlights that international technology transfer varies importantly across industries and countries.

    Analysing International Trade Patterns: Comparative Advantage for the World’s Major Economies

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    Using disaggregate product data classified by the Harmonized System code, this paper computes the revealed comparative advantage (RCA) for seven major economies that, when combined, contributed more than 80% of global manufacturing exports in 1996-97 and 2006-07. Results show that in the last decade, Canada, the US, and Japan have lost their share of global exports, while China has increased its share three-fold. These losses occurred mainly for low-tech products for the US, but medium and high-tech (MHT) products for Canada and Japan. However, MHT products comprise the highest share of Japanese exports (70%) compared to Canada (which has the lowest share, approximately half of Japan’s). Canada is the only economy whose contribution to global MHT exports is lower than that of global total exports. Japan also has the highest share of RCA-based MHT exports of other East Asian countries (OEACs) and the US. China has the highest share of non-RCA- based MHT exports. Finally, the trade patterns for OEACs and Mexico did not change greatly in any dimension in the last decade. However, products with RCA have changed substantially in all economies, with the highest in Mexico

    Estimating the Productivity Selection and Technology Spillover Effects of Imports

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    Economists emphasize two channels through which import liberalization affects productivity, one operating between and the other within firms. According to the former, import competition triggers market share reallocations between domestic firms with different technological capabilities (selection). At the same time, imports can also improve firms' technologies through learning externalities (spillovers). We present evidence for a sample of industrialized countries over the period 1973 to 2002. First, in the long run, import liberalization lowers productivity in domestic industries through selection. This finding confirms the prediction of models with firm heterogeneity, including Melitz and Ottaviano (2008), in which unilateral liberalization lowers the profits of domestic relative to foreign exporters. Second, if imports involve advanced foreign technologies, liberalization also generates technological learning that can on net raise domestic productivity. Third, for short time horizons of up to three years, a surge in imports typically raises domestic productivity. Because the number of firms at home and abroad does not change much in the short-run, new competition from foreign firms has a pro-competitive effect. We also find that high entry barriers, especially regulation, slow down the process of market share reallocation between firms. Over- all, the results support models in which trade triggers both substantial selection and technological learning.

    Sustainable Health in the Times of SDGs- Voices from the Margins

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    The present chapter reflects on health care availability, utilization and pattern of morbidity in the slum. The first part deals with the general profile of the public health, proximate causes of the ill health, which provides insight about the general profile of the infrastructure and basic amenities position vis a vis slum. The second part is related the health care utilization in slums namely services of the medical institutions, charges of the private medical institutions and clinics, source of treatment, reason for choosing the source of treatment, satisfaction with the treatment, user charge. This section also includes access to the health care services in the slums and the mode of transport used for the utilization of the health care services. The third aspect of the study is related to the pattern of morbidity in slums includes illness in the last month, ailment on the survey date, hospitalisation in one year, average morbidity and hospitalisation rate in one year of three slums, type of ailment, ailment of the head of the household, ailment of the family members, no of days of inactivity and lastly analysis of the common problems and health status of slum dwellers, treatment sought and the proximate reasons for the ailments in slums been done

    Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium

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    Several deleterious intra-acinar phenomena are simultaneously triggered on initiating acute pancreatitis. These culminate in acinar injury or inflammatory mediator generation in vitro and parenchymal damage in vivo. Supraphysiologic caerulein is one such initiator which simultaneously activates numerous signaling pathways including non-receptor tyrosine kinases such as of the Src family. It also causes a sustained increase in cytosolic calcium- a player thought to be crucial in regulating deleterious phenomena. We have shown Src to be involved in caerulein induced actin remodeling, and caerulein induced changes in the Golgi and post-Golgi trafficking to be involved in trypsinogen activation, which initiates acinar cell injury. However, it remains unclear whether an increase in cytosolic calcium is necessary to initiate acinar injury or if injury can be initiated at basal cytosolic calcium levels by an alternate pathway. To study the interplay between tyrosine kinase signaling and calcium, we treated mouse pancreatic acinar cells with the tyrosine phosphatase inhibitor pervanadate. We studied the effect of the clinically used Src inhibitor Dasatinib (BMS-354825) on pervanadate or caerulein induced changes in Src activation, trypsinogen activation, cell injury, upstream cytosolic calcium, actin and Golgi morphology. Pervanadate, like supraphysiologic caerulein, induced Src activation, redistribution of the F-actin from its normal location in the sub-apical area to the basolateral areas, and caused antegrade fragmentation of the Golgi. These changes, like those induced by supraphysiologic caerulein, were associated with trypsinogen activation and acinar injury, all of which were prevented by Dasatinib. Interestingly, however, pervanadate did not cause an increase in cytosolic calcium, and the caerulein induced increase in cytosolic calcium was not affected by Dasatinib. These findings suggest that intra-acinar deleterious phenomena may be initiated independent of an increase in cytosolic calcium. Other players resulting in acinar injury along with the Src family of tyrosine kinases remain to be explored. © 2013 Mishra et al
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