Violation of Bell's Inequalities with a Local Theory of Photons

We use a local theory of photons purely as particles to model the single-photon experiment proposed by Tan, Walls, and Collett. Like Tan et al. we are able to derive a violation of Bell's inequalities for photon counts coincidence measurements. Our local probabilistic theory does not use any specific quantum mechanical calculations.Comment: LaTeX, 11 pages, one figure (in LaTeX), submitted to Foundations of Physics Letter

Quantum cosmological perfect fluid model and its classical analogue

The quantization of gravity coupled to a perfect fluid model leads to a Schr\"odinger-like equation, where the matter variable plays the role of time. The wave function can be determined, in the flat case, for an arbitrary barotropic equation of state $p = \alpha\rho$; solutions can also be found for the radiative non-flat case. The wave packets are constructed, from which the expectation value for the scale factor is determined. The quantum scenarios reveal a bouncing Universe, free from singularity. We show that such quantum cosmological perfect fluid models admit a universal classical analogue, represented by the addition, to the ordinary classical model, of a repulsive stiff matter fluid. The meaning of the existence of this universal classical analogue is discussed. The quantum cosmological perfect fluid model is, for a flat spatial section, formally equivalent to a free particle in ordinary quantum mechanics, for any value of $\alpha$, while the radiative non-flat case is equivalent to the harmonic oscillator. The repulsive fluid needed to reproduce the quantum results is the same in both cases.Comment: Latex file, 13 page

Inequalities for dealing with detector inefficiencies in Greenberger-Horne-Zeilinger-type experiments

In this article we show that the three-particle GHZ theorem can be reformulated in terms of inequalities, allowing imperfect correlations due to detector inefficiencies. We show quantitatively that taking into accout those inefficiencies, the published results of the Innsbruck experiment support the nonexistence of local hidden variables that explain the experimental result.Comment: LaTeX2e, 9 pages, 3 figures, to appear in Phys. Rev. Let

Gla-rich protein is involved in the cross-talk between calcification and inflammation in osteoarthritis

Osteoarthritis (OA) is a whole-joint disease characterized by articular cartilage loss, tissue inflammation, abnormal bone formation and extracellular matrix (ECM) mineralization. Disease-modifying treatments are not yet available and a better understanding of osteoarthritis pathophysiology should lead to the discovery of more effective treatments. Gla-rich protein (GRP) has been proposed to act as a mineralization inhibitor and was recently shown to be associated with OA in vivo. Here, we further investigated the association of GRP with OA mineralization-inflammation processes. Using a synoviocyte and chondrocyte OA cell system, we showed that GRP expression was up-regulated following cell differentiation throughout ECM calcification, and that inflammatory stimulation with IL-1 beta results in an increased expression of COX2 and MMP13 and up-regulation of GRP. Importantly, while treatment of articular cells with gamma-carboxylated GRP inhibited ECM calcification, treatment with either GRP or GRP-coated basic calcium phosphate (BCP) crystals resulted in the down-regulation of inflammatory cytokines and mediators of inflammation, independently of its gamma-carboxylation status. Our results strengthen the calcification inhibitory function of GRP and strongly suggest GRP as a novel anti-inflammatory agent, with potential beneficial effects on the main processes responsible for osteoarthritis progression. In conclusion, GRP is a strong candidate target to develop new therapeutic approaches

Quantum gravity correction, evolution of scalar field and inflation

We take the first nontrivial coefficient of the Schwinger-DeWitt expansion as a leading correction to the action of the second-derivative metric-dilaton gravity. To fix the ambiguities related with an arbitrary choice of the gauge fixing condition and the parametrization for the quantum field, one has to use the classical equations of motion. As a result, the only corrections are the ones to the potential of the scalar field. It turns out that the parameters of the initial classical action may be chosen in such a way that the potential satisfies most of the conditions for successful inflation.Comment: 11 pages, 3 figure

Can biological quantum networks solve NP-hard problems?

There is a widespread view that the human brain is so complex that it cannot be efficiently simulated by universal Turing machines. During the last decades the question has therefore been raised whether we need to consider quantum effects to explain the imagined cognitive power of a conscious mind. This paper presents a personal view of several fields of philosophy and computational neurobiology in an attempt to suggest a realistic picture of how the brain might work as a basis for perception, consciousness and cognition. The purpose is to be able to identify and evaluate instances where quantum effects might play a significant role in cognitive processes. Not surprisingly, the conclusion is that quantum-enhanced cognition and intelligence are very unlikely to be found in biological brains. Quantum effects may certainly influence the functionality of various components and signalling pathways at the molecular level in the brain network, like ion ports, synapses, sensors, and enzymes. This might evidently influence the functionality of some nodes and perhaps even the overall intelligence of the brain network, but hardly give it any dramatically enhanced functionality. So, the conclusion is that biological quantum networks can only approximately solve small instances of NP-hard problems. On the other hand, artificial intelligence and machine learning implemented in complex dynamical systems based on genuine quantum networks can certainly be expected to show enhanced performance and quantum advantage compared with classical networks. Nevertheless, even quantum networks can only be expected to efficiently solve NP-hard problems approximately. In the end it is a question of precision - Nature is approximate.Comment: 38 page

MELISSA: System Description and Spectral Features of Pre- and Post-Midnight F-Region Echoes

Most of the low‐latitude ionospheric radar observations in South America come from the Jicamarca Radio Observatory, located in the western longitude sector (∼75°W). The deployment of the 30 MHz FAPESP‐Clemson‐INPE (FCI) coherent backscatter radar in the magnetic equatorial site of São Luis, Brazil, in 2001 allowed observations to be made in the eastern sector (∼45°W). However, despite being operational for several years (2001–2012), FCI only made observations during daytime and pre‐midnight hours, with a few exceptions. Here, we describe an upgraded system that replaced the FCI radar and present results of full‐night F‐region observations. This radar is referred to as Measurements of Equatorial and Low‐latitude Ionospheric irregularities over São Luís, South America (MELISSA), and made observations between March 2014 and December 2018. We present results of our analyses of pre‐ and post‐midnight F‐region echoes with focus on the spectral features of post‐midnight echoes and how they compare to spectra of echoes observed in the post‐sunset sector. The radar observations indicate that post‐midnight F‐region irregularities were generated locally and were not a result of “fossil” structures generated much earlier in time (in other longitude sectors) and that drifted into the radar field‐of‐view. This also includes cases where the echoes are weak and that would be associated with decaying equatorial spread F (ESF) structures. Collocated digisonde observations show modest but noticeable F‐region apparent uplifts prior to post‐midnight ESF events. We associate the equatorial uplifts with disturbed dynamo effects and with destabilizing F‐region conditions leading to ESF development

Gla Rich Protein (GRP) is associated to osteoarthritis being highly accumulated in the joint tissues and synovial fluid

info:eu-repo/semantics/publishedVersio

Quantum cosmological perfect fluid models

Perfect fluid Friedmann-Robertson-Walker quantum cosmological models for an arbitrary barotropic equation of state $p = \alpha\rho$ are constructed using Schutz's variational formalism. In this approach the notion of time can be recovered. By superposition of stationary states, finite-norm wave-packet solutions to the Wheeler-DeWitt equation are found. The behaviour of the scale factor is studied by applying the many-worlds and the ontological interpretations of quantum mechanics. Singularity-free models are obtained for $\alpha \alpha > - 1$.Comment: Latex file, 12 pages. New paragraphs in the Introduction and Conclusion, and other minor corrections in the text and in some formulas. Accepted for publication in General Relativity and Gravitatio