9 research outputs found

    2 Betaine-type Alkaloids From Egyptian Pancratium-maritimum

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    Two 2-oxyphenanthridinium alkaloids have been isolated from Egyptian Pancratium maritimum and identified as ungeremine and zefbetaine using spectroscopic and chemical methods. The identification of zefbetaine was supported by its partial synthesis from pseudolycorine and by comparison with its unnatural isomer, isozefbetaine, which was in turn prepared from sternbergine

    Narciclasine-4-o-beta-d-glucopyranoside, A Glucosyloxy Amidic Phenanthridone Derivative From Pancratium-maritimum

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    Bulbs of Pancratium maritimum were found to contain a new glucosyloxy phenolic metabolite as well as 14 known Amaryllidaceae alkaloids. The structure of the phenolic metabolite was elucidated by spectroscopic and chemical methods, and it was identified as narciclasine-4-O-beta-D-glucopyranoside. When tested in Artemia salina and potato disc assays the new glucoside showed cytotoxic and antitumour activity very similar to narciclasine
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