208 research outputs found

    On the energy-momentum tensor in non-commutative gauge theories

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    We study the properties of the energy-momentum tensor in non-commutative gauge theories by coupling them to a weak external gravitational field. In particular, we show that the stress tensor of such a theory coincides exactly with that derived from a theory where a Seiberg-Witten map has been implemented (namely, the procedure is commutative). Various other interesting features are also discussed.Comment: 3 page

    The use of HPV-DNA testing combined with Pap smear in detection of pre-invasive disease of the cervix

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    Background: Cancer cervix constitutes a major health problem worldwide. It is one of the most common female malignancy in both incidence and mortality. Cancer cervix has many risk factors, the most important one is persistent infection with one of HPV high risk types. Its morbidity and mortality can be reduced by frequent screening and early diagnosis. So that, several studies have been conducted in recent years in order to find better tests for screening for pre-invasive disease of the cervix and so early intervention and better prognosis. This study aimed to compare the sensitivity of Pap test and HPV DNA test as screening tests for pre-invasive disease of the cervix.Methods: 100 females from those attending Alexandria University gynaecologic clinic for causes rather than cancer cervix were subjected to Pap smear and cervical swab for HPV-DNA testing at the same setting. Cases of HSIL or positive HPV were subjected to VIA test, colposcopy and cervical punch biopsy was taken if aceto-whitening of the cervix or any other abnormality was found. Cases with ASCUS or LSIL were re-smeared after 3-6 months, if persistent or progressive pathology, colposcopy and punch biopsy from acetowhite areas were taken.Results: 21 cases (21%) were HPV positive and 66 cases (66%) were positive for intraepithelial lesions (37% ASCUS, 18% LSIL and 11% HSIL) with re-smearing there were 3 persistent ASCUS cases (8.1%) and 5 LSIL cases (27.78%). Colposcopy done, and biopsies were taken from 10 HSIL cases (90.1%), 5 LSIL (27.8%), 3 ASCUS (8.1%) and 10 HPV positive cases (62.5%). With significant relationship between colposcopic findings and HPV-DNA positivity and abnormal cytology. Biopsies were 18; 14 were CIN I and 4 were CIN II.Conclusions: HPV-DNA positivity has positive association with HSIL. Pap smear is an easy cheap method for screening. HPV-DNA test is less sensitive than cytology as a method for screening

    URINARY MARKERS OF OXIDATIVE DNA DAMAGE IN TYPE 1 DIABETIC CHILDREN: RELATION TO MICROVASCULAR COMPLICATIONS

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      Objective: Type 1 diabetes mellitus (T1DM) is a widespread metabolic disease, which frequently carries with it a significant impact on human health. Oxidative damage and tissue inflammation have been claimed to be a typical pathogenic component for the progression of diabetic complications. We aim in this study to explore the relation of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) (as a marker of nucleic acid oxidation) to microvascular complications in T1DM.Methods: A case–control study, enrolling 45 T1DM children and an equivalent number of healthy subjects, was performed. Full clinical examination and anthropometric measurement were performed to all subjects. Urinary assessment for 8-oxodG and albumin was done in addition to blood sampling for lipid profile and glycated Hb (HbA1c) assay. Complete ocular examination for assessment of diabetic retinopathy (DR) was also done.Results: Levels of urinary 8-oxodG, serum cholesterol, triglycerides, and low-density lipoprotein in cases were significantly higher than non-diabetics; these levels were likewise higher in uncontrolled T1DM patients in comparison with well-controlled T1DM subjects. Urinary 8-oxodG and HbA1c were significantly higher in diabetic patients with albuminuria and DR compared to patients without complications. Significant positive correlation was found between 8-oxodG with HbA1c (r=0.8, p<0.01), diastolic blood pressure (DBP) (r=0.4, p=0.02), and cholesterol (r=0.4, p=0.05).Conclusion: Urinary 8-oxodG was found to be a reliable marker for assessing oxidative DNA damage in T1DM and can be used in the determination of microvascular complications related to diabetes

    D-brane orbiting NS5-branes

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    We study real time dynamics of a Dp-brane orbiting a stack of NS5-branes. It is generally known that a BPS D-brane moving in the vicinity of NS5-branes becomes unstable due to the presence of tachyonic degree of freedom induced on the D-brane. Indeed, the D-brane necessarily falls into the fivebranes due to gravitational attraction and eventually collapses into a pressureless fluid. Such a decay of the D-brane is known to be closely related to the rolling tachyon problem. In this paper we show that in special cases the decay of D-brane caused by gravitational attraction can be avoided. Namely for certain values of energy and angular momentum the D-brane orbits around the fivebranes, maintaining certain distance from the fivebranes all the time, and the process of tachyon condensation is suppressed. We show that the tachyonic degree of freedom induced on such a D-brane really disappears and the brane returns to a stable D-brane.Comment: 12 pages, latex, added referenc

    Momentum modes of M5-branes in a 2d space

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    We study M5 branes by considering the selfdual strings parallel to a plane. With the internal oscillation frozen, each selfdual string gives a 5d SYM field. All selfdual strings together give a 6d field with 5 scalars, 3 gauge degrees of freedom and 8 fermionic degrees of freedom in adjoint representation of U(N). Selfdual strings with the same orientation have the SYM-type interaction. For selfdual strings with the different orientations, which could also be taken as the unparallel momentum modes of the 6d field on that plane or the (p,q) (r,s) strings on D3 with (p,q)\neq (r,s), the [i,j]+[j,k]\rightarrow [i,k] relation is not valid, so the coupling cannot be written in terms of the standard N \times N matrix multiplication. 3-string junction, which is the bound state of the unparallel [i,j] [j,k] selfdual strings, may play a role here.Comment: 37 pages, 5 figures, to appear in JHEP; v2: reference adde

    Making the hyper--K\"ahler structure of N=2 quantum string manifest

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    We show that the Lorentz covariant formulation of N=2 string in a curved space reveals an explicit hyper--K\"ahler structure. Apart from the metric, the superconformal currents couple to a background two--form. By superconformal symmetry the latter is constrained to be holomorphic and covariantly constant and allows one to construct three complex structures obeying a (pseudo)quaternion algebra.Comment: 8 pages, no figures, PACS: 04.60.Ds; 11.30.Pb, Keywords: N=2 string, hyper-K\"ahler geometry. Presentation improved, references added. The version to appear in PR

    Relativistic D-brane Scattering is Extremely Inelastic

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    We study the effects of quantum production of open strings on the relativistic scattering of D-branes. We find strong corrections to the brane trajectory from copious production of highly-excited open strings, whose typical oscillator level is proportional to the square of the rapidity. In the corrected trajectory, the branes rapidly coincide and remain trapped in a configuration with enhanced symmetry. This is a purely stringy effect which makes relativistic brane collisions exceptionally inelastic. We trace this effect to velocity-dependent corrections to the open-string mass, which render open strings between relativistic D-branes surprisingly light. We observe that pair-creation of open strings could play an important role in cosmological scenarios in which branes approach each other at very high speeds.Comment: 30 pages; added references and a comment about velocity-dependent masse

    The No-Triangle Hypothesis for N=8 Supergravity

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    We study the perturbative expansion of N=8 supergravity in four dimensions from the viewpoint of the ``no-triangle'' hypothesis, which states that one-loop graviton amplitudes in N=8 supergravity only contain scalar box integral functions. Our computations constitute a direct proof at six-points and support the no-triangle conjecture for seven-point amplitudes and beyond.Comment: 43page
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