Trial profile (ITT cohort).

<p>Trial profile (ITT cohort).</p

Psychomotor development of children by age and by their mother’s study group.

<p>Psychomotor development of children by age and by their mother’s study group.</p

Electrocardiogram readings.

<p>Electrocardiogram readings.</p

Nutritional outcomes of study infants by age and by their mother’s intervention group.

<p>Nutritional outcomes of study infants by age and by their mother’s intervention group.</p

Age category based parameter estimates from linear mixed model.

<p>Age category based parameter estimates from linear mixed model.</p

Patients’ flow.

<p>Patients’ flow.</p

Trial profile (modified intention-to-treat cohort).

<p>^aNumber of women recruited at first antenatal visit who did not attend the rest of the study visits but delivered at the maternity ward and for whom information on pregnancy outcome is available. ^bNumber of women who delivered before receiving second IPTp dose.</p

Adherence to cotrimoxazole categorized in tertiles.

a<p>OR of being in a given category or superior. ITT adjusted by country. ATP analysis adjusted by baseline variables (country, literacy, gestational age, gravidity, anemia, middle upper arm circumference, and CD4). Interaction MQ×country, <i>p</i>-value = 0.842 for ITT, <i>p</i>-value = 0.771 for ATP cohort.</p><p>Adherence to cotrimoxazole categorized in tertiles.</p

Baseline characteristics of mothers and infants.

<p>Baseline characteristics of mothers and infants.</p

Multivariate analysis of risk factors for mother to child transmission of HIV.

<p>Median age of infants was 5.9 weeks (IQR 1.7) at the time of the HIV PCR test. Analysis adjusted by baseline variables: country, literacy, gestational age, gravidity, anemia, middle upper arm circumference, CD4 counts and viral load. ITT analysis adjusted by country. ATP analysis adjusted by baseline variables: country, literacy, gestational age, gravidity, anemia, middle upper arm circumference, CD4 counts, and viral load.</p>a<p>At least one episode of clinical malaria during study follow-up in pregnancy.</p>b<p>Incomplete: received partially PMTCT (either antenatal, intrapartum, or postpartum) or ART.</p>c<p>Complete: received PMTCT (antenatal, intrapartum, and postpartum) or ART according to national guidelines.</p>d<p>The mother did not receive either PMTCT or ART.</p><p>Multivariate analysis of risk factors for mother to child transmission of HIV.</p