8 research outputs found
Üniversite Öğrencilerinin Yalnızlık Düzeylerinin Yordayıcısı Olarak Kişilik Özellikleri
Bu araştırmanın amacı, Beş Faktör Kuramına dayalı kişilik özelliklerinin (dışadönüklük, nevrotiklik, uyumluluk, sorumluluk, deneyime açıklık) üniversite öğrencilerinin yalnızlık düzeyleri üzerindeki yordama gücünü belirlemektir. Araştırmanın çalışma grubunu 2013-2014 eğitim-öğretim yılında İnönü ve Niğde Üniversitesinde öğrenim görmekte olan 433 (260 kız ve 173 erkek) öğrenci oluşturmuştur. Çalışmada, veri toplama araçları olarak UCLA Yalnızlık Ölçeği ve Beş Faktör Kişilik Envanteri kullanılmıştır. Araştırmada, veri analizi korelasyon ve çoklu regresyon analizi yöntemleriyle gerçekleştirilmiştir. Araştırma bulgularına göre dışadönüklük, nevrotiklik, uyumluluk ve deneyime açıklık kişilik özellikleri üniversite öğrencilerinin yalnızlık düzeylerinin anlamlı bir yordayıcısıdır. Sonuç olarak, Beş Faktör Kuramına dayalı kişilik özellikleri üniversite öğrencilerinin yalnızlık puanlarındaki varyansın % 28'ini açıklamıştırThe purpose of this study is to determine to what extent the personality traits based on conscientiousness, openness to experience) predict loneliness levels of university students. The study group of the research was composed of 433 students (260 female and 173 male students) who were attending Inonu University and Nigde University in the academic year of 2013-2014. As the data collection tools, the UCLA Loneliness Scale and the Five Factor Personality Inventory were used in the study. The data analysis was performed using correlation and multiple regression analysis methods. According to the findings of the research, the personality traits of extraversion, neuroticism, agreeableness, and openness to experience are significant predictors of university students' loneliness levels. Consequently, the personality traits based on the Five Factor Theory explained 28% of the variance in loneliness scores of university student
Associations between chronotype, sleep quality, suicidality, and depressive symptoms in patients with major depression and healthy controls
Research interest concerning associations between sleep characteristics and suicidality in psychopathology has been growing. However, possible linkages of suicidality to sleep characteristics in terms of sleep quality and chronotypes among depressive patients have not been well documented. In the current study, the authors investigated the possible effects of sleep quality and chronotype on the severity of depressive symptoms and suicide risk in patients with depressive disorder and healthy controls. The study was conducted on 80 patients clinically diagnosed with major depression and 80 healthy subjects who were demographically matched with the patient group. All participants completed a questionnaire package containing self-report measures, including the Beck Depression Inventory (BDI), Pittsburgh Sleep Quality Index (PSQI), Morningness-Eveningness Questionnaire (MEQ), and Suicide Ideation Scale (SIS), and subjects were interviewed with the suicidality section of the Mini-International Neuropsychiatric Interview (MINI). Results are as follows: (a) logistic regression analyses revealed that poor sleep quality and depression symptom severity significantly predicted onset of major depression; (b) morningness-type circadian rhythm may play as a significant relief factor after onset of major depression; (c) sleep variables of chronotype and sleep quality did not significantly predict suicide ideation after controlling for depressive symptoms in the major depression group; and (d) suicide ideation and poor sleep quality were antecedents of depression symptom severity in patients with major depression, and in healthy controls. Findings are discussed under the theoretical assumptions concerning possible relations between chronotype, sleep quality, depression, and suicidality
Magnetic Resonance Imaging in Children under Anesthesia: The Relationship between the Degree of Information Provided to Parents and Parents’ Anxiety Scores
Background. We aimed to investigate the correlation between the anxiety scores of parents whose children are administered anesthesia for magnetic resonance imaging (MRI) and the level of information provided to them before the MRI. The study included 146 children and their parents. The demographic information of the children and their parents was recorded. The parents were divided into two groups. In Group I, the patient’s medical history and physical exam findings were recorded on a standard consultation form by an anesthesiologist. In Group II, the parents were additionally provided with more detailed information on how the anesthesia would be administered and the drugs to be used and their side effects and complications. The anxiety scores of the parents were found to be lower in Group II. A higher level of education was associated with higher anxiety scores. Intergroup comparison detected lower anxiety scores for Group II parents whose education levels were up to high school. However, no change upon receiving detailed information was detected in the anxiety scores of parents with higher education levels. In conclusion, this may lower the anxiety scores in parents informed about details of anesthesia administration and may raise parents’ sense of confidence in the doctor
SİLAH RUHSATI RAPOR BAŞVURULARI: ŞANLIURFA ÖRNEĞİ
Amaç: Türkiye’de ateşli silah kullanımının ciddiboyutlardadır ve önemli bir halk sağlığı sorunuhaline gelmiştir. Bu çalışmada ki amacımız;Türkiye’de ateşli silahların en sık kullanıldığıillerinden biri olan Şanlıurfa’daki bir devlethastanesi sağlık kuruluna silah ruhsatı alımı içinbaşvuran kişilerin sosyodemografik özellikleriniincelemektir.Yöntemler: Şanlıurfa’daki bir devlet hastanesipsikiyatri polikliniğine silah ruhsatı almak içinsağlık kurulu raporuna başvuran bireyler çalışmayadâhil edildi. Hastaneye Ekim 2010- Mart 2012tarihleri arasında gerçekleşen 284 başvuruincelendi.Bulgular: Çalışmamızda başvuruların %95,4’ü(n=271) erkek, %4,6’ü (n=13) kadınlardan oluştuğugörülmektedir. Şahısların %12’si (n=34) 18-25,%28,5’ (n=81) 26-35, %27,1’i (n=77) 36-45,%21,5’I 46-55 (n=61) yaş aralığında ve %10,9’u(n=31) 56 yaşın üstündeydi. %89,4’ü evliydi.Başvuran kişilerin %42,2’si aylık bin liranın altındageliri olduğunu ifade ederken %30,4’ünün ise üçbin lira üstü geliri olduğu görüldü. Eğitimdurumuna bakıldığında %4,9’un (n=14) okumayazma bilmediği, %29,2’nin (n=146) ilköğretimmezunu, %30,6’sının (n=87) ortaöğretim ve kalan%13’ün (n=37) ise yüksek öğrenim gördüğüanlaşılmıştır. Başvuranlar tarafından silahlanmagerekçeleri olarak güvenlik %81,3, miras kalmışolması %4,2, riskli işte çalışıyor olma %4,9,komşusunda silah bulunması %2,8 ve diğernedenler %6,7 gösterildi. Şahısların yapılanpsikometrik incelemesi ve psikiyatrikdeğerlendirme neticesinde toplam %4,7’sinde(n=13) ruhsal hastalık olduğu tespit edildi.Sonuç: Silahlanma intihar, adam öldürme/yaralamagibi ciddi toplumsal sorunları artıran önemli birhalk sağlığı sorunudur. Çalışmamızda Şanlıurfa’dasosyoekonomik özelliklerine göre her kesimdensilah ruhsatı alımı için başvuruların olduğugörülmekte olup silahlanmanın bu ilimizde elealınması gereken ciddi bir halk sağlığı sorunuolduğu düşünülebilir. Ayrıca silah ruhsatı içinyapılan başvurularda ayrıntılı psikiyatrik muayeneve psikometrik inceleme yapılmalıdır.Anahtar kelimeler: Silah ruhsatı, sağlık kurulu,Şanlıurf
SOMATIC SYMPTOMS AND RELATED FACTORS OF EARLY-AGE MARRIAGE AMONG WOMEN: A POPULATION-BASED CROSS-SECTIONAL STUDY
Aim: Child marriage still persists for various reasons in numerous countries and cultures including primarily the underdeveloped or developing countries in South Asia and North Africa. In this study, our aim is to focus on the frequency of child marriage as well as the family characteristics and socio-cultural factors pertaining to marriage, frequency of domestic violence, and somatic symptoms such as pain of unknown origin among the women.Methods: Our study was conducted using a questionnaire presented to 454 women aged 17-65 living in the provincial centre of Diyarbakir.Results: The families of 17.3% of the participants had a history of migration before the marriage. Close-kin marriage was present between the parents of 31.1% of the women. Among the participants, 17.3% were subjected to physical abuse and 1.8% were subjected to sexual abuse before the marriage. Among the women, 33.3% replied that they had chronic pain of unknown origin which the physicians could not diagnose.Conclusions: We have observed that chronic pains of unknown origin pointing to somatisation are more frequent among women who get married before the age of 18. The results of our study point out that underage marriage has an impact not only on sexual and reproductive health, but also on general health.Key Words: Early age marriage, health consequences, pain of unknown origi
Synthesis, anticancer evaluation and molecular docking studies of new benzimidazole- 1,3,4-oxadiazole derivatives as human topoisomerase types I poison
In this study, some benzimidazole-oxadiazole derivatives were synthesised and tested for their in vitro anticancer activities on five cancer cell lines, including HeLa, MCF7, A549, HepG2 and C6. Their structures were elucidated by IR, 1H-NMR, 13C-NMR, 2 D-NMR and HRMS spectroscopic methods. Among all screened compounds; 5a, 5b, 5d, 5e, 5k, 5l, 5n and 5o exhibited potent selective cytotoxic activities against various tested cancer cell lines. Especially, compounds 5l and 5n exhibited the most antiproliferative activity than Hoechst 33342 and doxorubicin against HeLa cell line, with IC50 of 0.224 ± 0.011 µM and 0.205 ± 0.010 µM, respectively. Furthermore, these potent lead cytotoxic agents were evaluated in terms of their inhibition potency against Topoisomerase I and it was determined that selected compounds inhibited the Topoisomerase I. Docking studies were performed and probable interactions in the DNA-Topo I enzyme complex was determined