Pemberdayaan Siswa Sekolah Dasar Dalam Pelatihan Dan Edukasi Apoteker Cilik Dalam Rangka Pencapaian Desa Peduli Kesehatan Di Kecamatan Pagimana

Apoteker merupakan tenaga kesehatan yang memiliki keahlian di  bidang  obat-obatan. Banyaknya masyarakat yang  belum  mengenal  profesi  apoteker.  Melalui  apoteker  cilik  ini  kita  berusaha  untuk  mengenalkan  profesi  apoteker  sebagai  salah  satuvtenaga  kesehatan yang  memiliki  keahlian  dibidang  penggunaan  obat kepada  masyarakat.  Penting  untuk bisa memberikan pengenalan terhadap dunia kesehatan pada anak-anak sejak mereka kecil,  salah satunya melalui program apoteker cilik. Saat  ini,  pemberdayaan  program  pendidikan kesehatan  serta pelayanan  kesehatan  di  usia dini  terutama  di  level    sekolah  dasar  (SD)  telah  mulai  berkembang.  Tujuan  kegiatan  pengabdian  kepada  masyarakat  ini  adalah  memperkenalkan  profesi  apoteker  sebagai  salah  satu  tenaga  kesehatan  dan  sumber  informasi  obat  serta  memberikan  pelatihan  keterampilan  dan  edukasi  tentang  penggunaan  obat  yang  tepat Pelaksanaan pengabdian kepada masyarakat di Sekolah Dasar  desa Taloyon dan desa Sepa Kecamatan Pagimana.Pengenalan kepada anak usia dini dalam memperkenalkan profesi Apoteker kepada siswa SD dapat meningkatkan pengetahuan masyarakat atas profesi Apoteker, serta memperkenalkan istilah Apoteker Cilik akan meningkatkan popularitas profesi Apoteker. Edukasi obat kepada anak usia dini harus terus ditingkatkan supaya membawa perubahan mindset mengenai pengetahuan dan kesadaran tentang penggunaan obat secara tepat

THE EFFECT OF SEA CUCUMBER (HOLOTHURIA SCABRA) EXTRACT AS HEPATOPROTECTIVE: HISTOPATHOLOGICAL STUDY

Objective: Sea cucumber Holothuria scabra is one of the marine animals that can be consumed as food and also efficacious as a drug. One of the benefits of sea cucumber has high cell regeneration ability. This study aims to see the profile of hepatoprotective histology of sea cucumber extract on mice that have been given paracetamol toxic dose.Methods: This experiment was conducted using experimental animal grouped of mice which were divided into six groups: Group I: sea cucumber extract 1%, Group II: 1000 mg/kg body weight (BW) or 25 mg/25 g BW, Group III: 750 mg/kg BW or 18.75 mg/25 g BW, Group IV: 500 mg/kg BW or 12.5 mg/25 g BW, Group V: positive control (curcuma tablet 2.5 mg/25 g BW), and Group VI: paracetamol group (62,5 mg/25 g BW). The histopathology test was performed to see the improvement of liver necrosis of mice.Results: The results of histopathological study showed that all groups of mice livers experienced necrosis (cell damage) and abnormalities. In the group of sea cucumber extract having dose 500 mg/kg BW, liver cells experienced degeneration of fat and hemorrhage as in the group of curcuma tablet, but in Group VI (paracetamol group), liver of mice experienced apoptosis (cell death). In the histopathology test, results can also be seen that in Group IV at doses of 500 mg/kg BW, the liver experienced slightly less severity than all other groups.Conclusion: The sea cucumber at doses of 500 mg/kg BW can improve the hepatic damage on mice induced by paracetamol

Evaluasi Mutu Pelayanan Kefarmasian Berdasarkan Standar Pelayanan Minimal (Spm) Di Instalasi Farmasi

Quality refers to compliance with predetermined standards or by requirements. The minimum service standard (MSS) in the health sector at the hospital is crucial because it is a measure of the hospital's performance of health services. This study was intended to describe the service quality in the pharmacy installation of Toto Hospital in Kabila based on four indicators of minimum pharmacy service standards, viz. drug waiting time for treatment completion, the absence of drug administration errors, customer satisfaction, and prescription writing according to the formulary. This descriptive cross-sectional research involved 154 outpatients and inpatients for the category of prescription writing according to the formulary and 154 outpatients for other categories as respondents as samples. Besides, the instruments were a customer satisfaction questionnaire and observation sheet. The results showed that the indicators of waiting time were nine minutes seven seconds and 18 minutes six seconds for concocted drug treatment; there was no error in administering drugs by 100%; customer satisfaction was 86.9%, and; prescription writing according to the formulary was 92.7%. . It was concluded that the Pharmacy Installation of Toto Hospital had not met the specified Minimum Service Standards (MSS)

Uji Efektivitas Ekstrak Etanol Kulit Batang Kersen (Muntingia calabura L.) Sebagai Antidiabetes Pada Mencit Jantan

Diabetes is a degenerative disease characterized by high levels of glucose in the blood. Diabetes can lead to complications if left untreated. Treatment of diabetes can be done pharmacologically (using traditional medicines or synthetic) or non- pharmacologically (accustoming a healthy lifestyle). The use of traditional medicines is relatively cheap compared to synthetic drigs so that can be used as an anti-diabetic is the Jamaica Cherry (Muntingia calabura L.), as it contains secondary metabolites tha act as antidiabetics. Therefore, this present research aimed to determine the as an antidiabetic in male mice. The research methods used were maceration, phytochemical screening, anti-diabetic test with pre test and post test control design methods to determine if there was a decrease after the administration of the extract. The finding depicted that in the phytochemical screening test, it was observable that Jamaica Cherry (Muntingia calabura L.) bark contained secondary metabolites, incluiding alkaloids, flavonoids, and tannins, while the antidiabetic test indicated that all four extract with concentration of 50 mg, 100 mg, 200 mg and 400 mg were effective to reduce the blood sugar level with each percentage of 9%, 16%, 26%, and 42%. In brief, the antidiabetic compounds that play a role in the ethanol extract of Jamaica Cherry (Muntingia calabura L.) bark were flavonoids and tannins

UJI EFEKANTIINFLAMASI EKSTRAKETANOL BUNGA ROSELA(HIBISCUS sabdariffa Linn.)PADA TIKUS PUTIH JANTAN (Rattus norvegicus)

An antiinflamatory effect test ofroselaflowers (hibiscus sabdwiffa Linn.) on male rats (Rattus norvegicus)had been carried out. The aim ofthis research is to assay anti-inflamatory effect of rosela extract flowers based on the reduction volume of legs edema inmale rats which induced with albumin 15 male rats divided into 5 groups and each group consisted of 3 rats. control group was given Na-CMC 1% w/v, 2nd ,3\'d and 4 groups were given rosela extract. flowers each 2,5% w/v, 5% w/v and 7,5% respsctively and 5th group was given natrium diclofenac suspension as psitive control. All treatment were given orally with dosage 5 mL/400g body weight. Legs of male rats was signed and measured as first volume using platysmometer, one hour later 0,2 mL albumin sohrtion 1% v/v wasinjected by intraplantary into legs of male rats to induce inflammation and measured as edema volume.Measurement of legs volume was conduct 3 hours with interval 30 minutes. The resrlts showed that all the concentration ofrosella extract flowers were reduced the edema volum, the effect ofreduction edema volume rosela extract flowers 7,5% w/v better than the effect of diclofenac suspension statifically

Pelatihan Kader dalam Rangka Pembentukan Forum Tangguh Cegah Stunting di Desa Dutohe Barat, Kecamatan Kabila, Kabupaten Bone Bolango

Hasil Studi Status Gizi Balita Indonesia (SSGBI) tahun 2019 menunjukan telah terjadi penurunan prevalensi Stunting dari 30,8% tahun 2018 menjadi 27,67% tahun 2019. Meski menurun, angka ini masih dinilai tinggi, karena angka toleransi WHO untuk Stunting sebesar 20 %. Kondisi ini diperberat dengan adanya pandemi COVID-19, yang menyebabkan banyak pemutusan hubungan kerja (PHK) sehingga pengangguran meningkat dan akibatnya daya beli masyarakat khususnya pangan menurun. Secara tidak langsung berdampak pada peningkatan kejadian Stunting.  Provinsi Gorontalo termasuk provinsi dengan jumlah penduduk muda yang signifikan. Sebanyak 395.000 orang atau 35 persen dari total penduduk di provinsi ini adalah anak-anak. Dua dari tiga anak tinggal di wilayah perdesaan. Gorontalo merupakan salah satu provinsi yang memiliki masalah Stunting di Indonesia. Pada tahun 2018 provinsi Gorontalo masih tinggi angka Stunting yaitu di Kabupaten Bone Bolango, angka prevalensi Stunting di Bone Bolango cukup tinggi, yaitu 25,1%. Angka itu masih di atas angka standar yang ditoleransi World Health Organization (WHO), yaitu di bawah 20%. Tujuan pelaksanaan KKN Profesi Kesehatan ini yakni terbentuknya kader kesehatan peduli stunting. Program KKN Profesi Kesehatan dilaksanakan selama 45 hari, bersama Dosen Pembimbing Lapangan dan 13 orang mahasiswa, diharapkan dapat menjadi solusi alternatif yang ditawarkan untuk meningkatkan kualitas pelayanan terhadap masyarakat, khususnya dalam bidang kesehatan dalam Percepatan Penurunan Stunting Di Kabupaten Bone Bolango. Hasil yang ditargetkan dalam program ini yakni meningkatnya produktifitas pengabdian dosen kepada masyarakat serta mendorong terwujudnya peningkatan derajat kesehatan masyarakat melalui kader Kesehatan sehingga memiliki kesiapsiagaan yang baik dalam menangani dan mencegah stunting.

Potensi Ekstrak Biji Pala (Myristica fragrans L) Terhadap Penyembuhan Luka Bakar pada Mencit (Mus musculus)

The Nutmeg Plant (Myristica Fragrans L) is one of the spices plants empirically used as a therapeutic option for injury healing. Burn injury is damage to the skin's integrity caused by contact with a source with a high-temperature difference. This research aimed to determine the effectiveness of Nutmeg (Myristica Fragrans L) Seed extract on burn injury healing in Male Mice (Mus Musculus). Extraction was carried out through Maceration with Methanol solvent. Eighteen mice were divided into 6 groups: negative control (Na-CMC), positive control (Bioplacenton), and treatment groups with concentrations of 3%, 5%, 7%, and 10%. Burn injury was created using a 2 cm x 2 cm iron plate on the mice's back, and the healing of the burn injury diameter was observed from day 1 to day 20, with observation intervals at day 5, 10, 15, and 20. The data were analyzed using one-way ANOVA followed by an LSD test to determine the differences between test groups. The resalts indicate that the ethanol extract of Nutmeg (Myristica Fragrans L) see haseng effect on burn injury, with the most effective concentration being the extraet onoration of 10%, with a burn injury healing rate of up to 89,15%

Uji Toksisitas Ekstrak Etanol Kulit Terong Ungu (Solanum melongena L.) Menggunakan Metode Brine Shrimp Lethality Test (BSLT)

Purple eggplant skin (Solanum melongena L.) is one of the herbal plants that contain compounds such as flavonoids, alkaloids, saponnins, tannins, and terpenoids that are beneficial for health. This research is a laboratory experimental study that aims to determine the level of acute toxicity (LC50) of the ethanol extract of purple eggplant skin (Solanum melongena L.) using the Brine Shrimp Lethality Test (BSLT) method. Purple eggplant peel extraction was carried out using 70% ethanol as solvent. This test was conducted using 10 Artemia salina Leach larvae with 3 replications at 6 concentration variants, which are 500 ppm, 250 ppm, 125 ppm, 50 ppm, 25 ppm, and 12.5 ppm, along with negative controls. The larval mortality rate was observed after 24 hours of adding extract. The result of probit analysis showed that the LC50 value of the ethanol extract of purple eggplant skin (Solanum melongena L.) was 100.8 ppm. Moreover, the results of LC50 1000 ppm indicated that the ethanol extract of purple eggplant skin (Solanum melongena L.) was considered toxic and potential to be an anticancer agent

Edukasi Penggunaan Obat Antidiabetes di Bulan Ramadhan pada Masyarakat Desa Buata Kecamatan Botupingge

Permasalahan utama pasien Diabetes Melitus (DM) adalah kepatuhan dalam minum obat dalam jangka Panjang. Pasien diabetes melitus yang mendapat terapi obat antidiabetes oral yang dapat menjalankan ibadah puasa di bulan Ramadhan harus mengikuti aturan baru minum obat, sehingga perlu diberikan informasi mengenai aturan minum obat yang tepat. Pemberian informasi melalui penyebaran brosur merupakan salah satu cara yang paling efektif untuk memperkenalkan aturan pemberian obat yang benar. Kegiatan tersebut berlokasi di Desa Buata, Kecamatan Botupingge, Kabupaten Bone Bolango. Hasil dari kegiatan ini, penderita diabetes melitus lebih siap menghadapi Ramadhan dengan aturan baru minum obat anti diabetes