361 research outputs found

    TRUNCATED-AT-ZERO COUNT DATA MODELS WITH PARTIAL OBSERVABILITY: AN APPLICATION TO THE FRESHWATER FISHING DEMAND IN THE SOUTHEASTERN U.S.

    Get PDF
    We extend the double-hurdle count data model to account for a joint decision in the first stage in which the individual jointly makes a decision about a participation in fishing and a site (region) selection decision. Contrary to the conventional the double-hurdle count data model, our model discriminates between the effects of non-participant and potential participants (e.g., potential participants are those who participated in fishing but may or may not take a trip to a specific site, the Southeastern U.S.) on the probability of taking a fishing trip.Consumer/Household Economics,

    Growth Expectations and Decision to Renovate a Golf Course: An Application of a Censored Model with the Simultaneity Test

    Get PDF
    Golf course renovation and expected business growth were examined. Endogeneity test on the renovation decision and a censored expected growth model rejected the hypothesis of simultaneity and decisions were modeled separately. Key determinants for both decisions were golf facility features, but not respondents' characteristics.Research Methods/ Statistical Methods,

    APPLICATION OF HURDLE NEGATIVE BINOMIAL COUNT DATA MODEL TO DEMAND FOR BLACK BASS FISHING IN THE SOUTHEASTERN UNITED STATES.

    Get PDF
    This paper identifies factors that influence the demand for a black bass fishing trip taken in the Southeastern U.S. using a double hurdle negative binomial count data model. The probability of fishing for a black bass is estimated in the first stage and the trip frequency for fishing a black bass is estimated in the second stage given that the individual has a positive probability towards undertaking a black bass fishing trip in the Southeast. The applied approach allows the decomposition of the effects of factors responsible for the decision of taking a fishing trip and the number of trips.Consumer/Household Economics,

    Trends of Protein Aggregation in Neurodegenerative Diseases

    Get PDF
    Protein aggregation trends in neurodegenerative diseases are largely unmapped due to the complex nature of protein-protein interactions and their regulatory machineries such as protein proteolytic systems. Since the protein aggregation process in humans is a slow process, early determination of the patients that will develop neurodegenerative diseases later in life is critical in terms of starting effective treatment, which will reduce the expensive health care. In this chapter, I will discuss the nature of protein aggregation of signature proteins and the status of protein proteolytic systems such as proteasome and autophagosome in Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, frontotemporal lobar degeneration, Huntington’s disease, and prion disease under the light of recent studies including our new findings

    Marketing Portfolio Choices by Independent Peach Growers: An Application of the Polychotomous Selection Model

    Get PDF
    In selecting a marketing channel for fresh peach sales, Georgia commercial peach growers choose the channel after accounting for buyers' preferences for quality attributes. Using the polychotomous selection model and survey data we identified external and internal quality attributes as essential factors influencing the choice of a marketing channel and the share of the crop marketed. Other factors influencing the choice and the volume sold through each marketing channel included orchard characteristics and the variety-determined fruit maturity.Marketing,

    EXAMINATION OF TEACHER CANDIDATES’ ATTITUDES, EMOTIONS, AND ANXIETIES REGARDING INCLUSIVE EDUCATION BY DIFFERENT VARIABLES

    Get PDF
    To benefit teaching-learning processes, Individuals needing special education must be placed in suitable education environments after educational identification and evaluation processes. The least restrictive environment approach was employed considering peer interaction and academic skills. Inclusive education is one of the most chosen least restrictive environments. Studies have suggested that inclusive education is beneficial for both the typical students and students with special needs. It is stated that the main element in the success of inclusive education is the teacher. Because teachers prepare, apply, monitor and evaluate the individualized educations programs which are suitable for the needs and characteristics of students with special needs. In this respect, it is known that the attitudes, emotions, and anxieties of teachers towards inclusive education are significant factors (Salend and Duhaney, 1999; Şekercioğlu, 2010; Diken, 1999). Many studies can be found on inclusive education but few of them are about the emotions, attitudes, and anxieties of teacher candidates towards inclusive education. So, this study aims to examine the emotions, attitudes, and anxieties of teacher candidates towards inclusive education by different variables such as gender, the department they are studying in, inclusive education legislation knowledge, and having been interacted with an inclusive student before. The relational screening model one the descriptive survey model was used in this study. 600 teacher candidates studying in ten different departments participated in the study. Data were collected through “Scale for Emotions, Attitudes, and Anxieties Regarding Inclusive Education” developed by Chris Forling et al. (2011) and adapted to Turkish by Bayar et al. (2015). Data were analyzed through SPSS. Independent samples t-test was used to reveal the differentiation in terms of gender and having an interaction before variables. One-way analysis of variance was applied to reveal the differentiation in terms of the legislation knowledge and department variables. Tukey test was performed to find the reason for the differentiation. The results revealed that there is no significant difference between gender and attitudes, emotions, and anxieties of teacher candidates, but that there is a significant difference between the having an interaction with inclusive students before, inclusive education legislation knowledge, the department they are studying in variables and attitudes, emotions, and anxieties of teacher candidates. It is understood that activities towards inclusive education in teaching practice course must be increased and the undergraduate programs must include a course regarding inclusive education.  Article visualizations

    THE COMMUNICATION BETWEEN PARENTS WITH SPECIAL NEEDS CHILDREN AND THEIR TYPICALLY DEVELOPING CHILDREN IN TURKEY

    Get PDF
    In Turkey, whereas there are a number of studies which examine the communication of parents with their typically developing children, there are limited studies which examine the communication of parents with special needs children with their typically developing children. Therefore, the main purpose of this study is to investigate the communication of parents with special needs children with their typically developing children. 295 parents who have both mentally disabled and typically developing children participated in the study in the 2019-2020 academic year. The data in the study were obtained by using the Parent-Child Communication Scale (PCCS) developed by Kahraman (2016). The scale consisting of 27 items contains 5 sub-dimensions and explains .54,3 of the total variance. For the overall reliability, the Cronbach’s alpha was .865. The data were analyzed by using the statistical techniques included in the SPSS program to analyze the data collected through the scale. There are two main objectives in the study: to explore the communication of parents with special needs children with their typically developing children in terms of various variables, and relationship between perception of problem-solving and unobstructed listening, open to share, respect-acceptance and sensitivity, which are among to the subscales of PCCS. As a result of the research, it was revealed that there was a significant difference between the genders, ages, education status, disability status of their special needs children and their monthly income levels of parents with special needs children and their communication levels with their typically developing children. As the perception of problem-solving increased in the communication of parents with special needs children with their typically developing children. However, there was no correlation between the perception of problem-solving and unobstructed listening skills of parents with special needs children with their typically developing children.  Article visualizations

    THE ASSOCIATION BETWEEN ALTMETRIC, PLUMX METRICS AND CITATION COUNT OF PUBLICATIONS: A CROSS-SECTIONAL STUDY AMONG TOP CHILD AND ADOLESCENT PSYCHIATRY JOURNALS

    Get PDF
    Background: Altmetric Attention Score (AAS) and PlumX Metrics are becoming important to evaluate the impact of the publication in addition to classical scientific rating method such as citation count and impact factor. These metrics collect data about publications’ tweet count, Facebook interaction count and other social interactions. In this study, it is aimed to examine the association between AAS, PlumX Metrics and citation count of top child and adolescent psychiatry. Methods: We identified the five journals and retrospectively analysed the publications published in 2019. All the original research articles, met analysis, and reviews were analysed. The articles were divided into two groups as original articles/research articles and meta-analysis/systematic review. We have hypothesized that there could be a positive correlation between AAS and PlumX Metrics data and citation count among these journals and there could be a difference between AAS, PlumX scores and citation count between original articles/research articles and meta-analysis/systematic review as their reading potential is different. Results: We have found a significant positive correlation between citation count, AAS and PlumX Metrics. This association continued after controlling the journal impact factor. In linear regression analysis, type of publication, total count of tweets, and Mendeley reads predicted the citation count. Conclusion: In addition to the classical methods measuring the quality of the articles such as the total citation count and impact factor, the importance of AAS and PlumX Metrics has been increasing. It is important to share scientific publications on these platforms in order to increase the impact of the articles

    Neuroprotective effects of ferulic acid and thymoquinone against deltamethrin-induced neurotoxicity in Drosophila melanogaster

    Get PDF
    Background: Recent research indicates a link between exposure to pyrethroid pesticides and negative neurodevelopmental outcomes such as neurodegenerative disorders, low intelligence quotient (IQ), and attention disorders. Thus this study aims (1) to investigate the effect of exposing Drosophila melanogaster adult male flies to 0.59 µM deltamethrin (DLM) for 24 h on their survival, climbing behavior, and acetylcholinesterase (AChE) activity, as well as the gene expression levels of ple, ddc, dat, aanat1, dop1r1, dop2r, and dopecr genes, and (2) to assess the protective effect of 250 µM Ferulic acid (FA), 25 µM Thymoquinone (TQ), and their combinations on the survival, climbing behavior, and AChE activity of D. melanogaster adult male flies exposed to 0.59 µM DLM for 72 h.Methods: In the first experiment, adult male wild-type flies were exposed to DLM incorporated into a 10% sucrose solution for 24 h, whereas, in the second experiment, they were exposed to DLM and the individual neuroprotective agents, or their mixture for 72 h.Results: Flies exposed to DLM exhibited higher mortality rates and shorter climbing distances in the negative geotaxis assay compared to control flies. Additionally, exposure to DLM upregulated the genes ddc, dat, dop1r1, dop2r, and dopecr significantly. Moreover, exposure to DLM for 72 h resulted in higher mortality rates and severe locomotor defects. However, the neuroprotective agents were effective in mitigating these toxic effects. While DLM inhibited AChE activity, concurrent exposure to FA ameliorated the inhibition.Conclusion: This study demonstrates the efficacy of natural compounds in reducing DLM-induced toxicity in D. melanogaster and highlights the potential use of this model in studying and developing therapeutic strategies for movement disorders.Keywords: Drosophila melanogaster; Neurotoxicity; Ferulic acid; Thymoquinone; Deltamethrin; Negative geotaxis    

    Caenorhabditis Elegans and Angiogenesis

    Get PDF
    DergiPark: 541687tmsjAbstract: Angiogenesis is sprouting of new capillaries from already existing ones. It is a dynamic process that can be seen in every phase of human life. It is among the dynamic mechanisms of both physiological and pathological processes. Vascular endothelial growth factor is one of the many molecules that play a role in angiogenesis. Vascular endothelial growth factor is released specifically to the endothelium. It regulates mitogenesis, vascular tone, vascular permeability and vasodilatation in the vascular endothelium. Caenorhabditis elegans is a nematode used to detect and screen the developmental processes and genetic mutations. It is appropriate to study at the organism level to isolate cells and to demonstrate intercellular interactions in vivo. Polyvinyl fluoride-1 is a molecule that plays a role in the neural development of Caenorhabditis elegans. In addition, the polyvinyl fluoride-1 molecule is told to be effective in angiogenesis. Studies have shown that polyvinyl fluoride-1 binds to vascular endothelial growth factor receptor-1 and vascular endothelial growth factor receptor-2, but not to vascular endothelial growth factor receptor-3 and platelete derivated growth factor receptor ?. In the research of human umbilical vein endothelial lines, it was observed that polyvinyl fluoride-1 induced angiogenesis and vascular tube formation. These results suggest that Caenorhabditis elegans may have a very important role in vascular endothelial growth factor studies. Caenorhabditis elegans model is used in many scientific areas such as aging, nervous system and genetic changes. However, only a few laboratories around the world studied the Caenorhabditis elegans angiogenesis model. Besides, this model is not currently used in Turkey. This provides a great advantage in terms of the utilization of this model in angiogenesi
    • …
    corecore