21 research outputs found
Design, Analysis and Testing of a Novel Mitral Valve for Transcatheter Implantation
Mitral regurgitation is a common mitral valve dysfunction which may lead to heart failure. Because of the rapid aging of the population, conventional surgical repair and replacement of the pathological valve are often unsuitable for about half of symptomatic patients, who are judged high-risk. Transcatheter valve implantation could represent an effective solution. However, currently available aortic valve devices are inapt for the mitral position. This paper presents the design, development and hydrodynamic assessment of a novel bi-leaflet mitral valve suitable for transcatheter implantation. The device consists of two leaflets and a sealing component made from bovine pericardium, supported by a self-expanding wireframe made from superelastic NiTi alloy. A parametric design procedure based on numerical simulations was implemented to identify design parameters providing acceptable stress levels and maximum coaptation area for the leaflets. The wireframe was designed to host the leaflets and was optimised numerically to minimise the stresses for crimping in an 8 mm sheath for percutaneous delivery. Prototypes were built and their hydrodynamic performances were tested on a cardiac pulse duplicator, in compliance with the ISO5840-3:2013 standard. The numerical results and hydrodynamic tests show the feasibility of the device to be adopted as a transcatheter valve implant for treating mitral regurgitation
Embolic protection devices during TAVI: current evidence and uncertainties
Abstract not availableOmarAbdul-Jawad Altisent, Rishi Puri, Josep Rodés-Caba
Valve thrombosis following transcatheter aortic valve implantation: a systematic review
Title in Spanish: Revisión sistemática de la trombosis protésica tras implante percutáneo de válvula aórtica. Abstract published in English and Spanish.Abstract not availableJuan G. Córdoba-Soriano, Rishi Puri, Ignacio Amat-Santos, Henrique B. Ribeiro, Omar Abdul-Jawad Altisent, María del Trigo, Jean-Michel Paradis, Eric Dumont, Marina Urena, Josep Rodés-Caba
First-in-man experience of a novel transcatheter repair system for treating severe tricuspid regurgitation
Abstract not availableFrancisco Campelo-Parada, Gidon Perlman, François Philippon, Jian Ye, Christopher Thompson, Elisabeth Bédard, Omar Abdul-Jawad Altisent, Maria Del Trigo, Jonathon Leipsic, Philipp Blanke, Danny Dvir, Rishi Puri, John G. Webb, Josep Rodés-Caba
Incidence and risk factors of hemolysis after transcatheter aortic valve implantation with a balloon-expandable valve
Abstract not availableJérôme Laflamme, Rishi Puri, Marina Urena, Louis Laflamme, Hugo DeLarochellière, Omar Abdul-Jawad Altisent, Maria del Trigo, Francisco Campelo-Parada, Robert DeLarochellière, Jean-Michel Paradis, Eric Dumont, Daniel Doyle, Siamak Mohammadi, Mélanie Côté, Philippe Pibarot, Vinçent Laroche, Josep Rodés-Caba