2 research outputs found
A Borane Platinum Complex Undergoing Reversible Hydride Migration in Solution
Reaction of [PtÂ(κ<sup>2</sup>-<i>C</i>,<i>N</i>-ppy)Â(dmso)ÂCl], <b>1</b> (Hppy = 2-phenylpyridine), with NaÂ[H<sub>2</sub>BÂ(mb)<sub>2</sub>] (Hmb = 2-mercapto-benzimidazole) smoothly afforded the complex
{[(κ<sup>3</sup>-<i>S</i>,<i>B</i>,<i>S</i>-HBÂ(mb)<sub>2</sub>]ÂPtÂ(κ<sup>2</sup>-<i>C</i>,<i>N</i>-ppy)ÂH}, <b>2</b>, featuring a strong reverse-dative
Pt → B σ interaction in the solid state. When dissolved
in thf (or acetone) solution, <b>2</b> undergoes a reversible
Pt–H bond activation, establishing an equilibrium between the
hexacoordinated <b>2</b> and the tetracoordinate complex {[(κ<sup>2</sup>-<i>S</i>,<i>S</i>-H<sub>2</sub>BÂ(mb)<sub>2</sub>]ÂPtÂ(κ<sup>2</sup>-<i>C</i>,<i>N</i>-ppy)}, <b>3</b>, as ascertained by multinuclear NMR. Hydrolysis
of the B–N bond in <b>2</b>/<b>3</b> resulted ultimately
in the formation of a dimeric half-lantern platinumÂ(II,II) complex
[{PtÂ(κ<sup>2</sup>-<i>C</i>,<i>N</i>-ppy)Â(μ<sub>2</sub>-κ<sup>2</sup>-<i>N</i>,<i>S</i>-mb)}<sub>2</sub>], <b>4</b>. The SC-XRD structures of <b>2</b> and <b>4</b> are reported
Biocompatible 3D Liquid Crystal Elastomer Cell Scaffolds and Foams with Primary and Secondary Porous Architecture
3D
biodegradable and highly regular foamlike cell scaffolds based
on biocompatible side-chain liquid crystal elastomers have been prepared.
Scaffolds with a primary porosity characterized by spatially interlaced,
interconnected microchannels or an additional secondary porosity featuring
interconnected microchannel networks define the novel elastomeric
scaffolds. The macroscale
morphology of the dual porosity 3D scaffold resembles vascular networks
observed in tissue. 3D elastomer foams show four times higher cell
proliferation capability compared to conventional porous templated
films and within the channels guide spontaneous cell alignment enabling
the possibility of tissue construct fabrication toward more clinically
complex environments