Contraction of the G_r,s Quantum Group to its Nonstandard analogue and corresponding Coloured Quantum Groups

The quantum group G_r,s provides a realisation of the two parameter quantum GL_p,q(2) which is known to be related to the two parameter nonstandard GL_hh'(2) group via a contraction method. We apply the contraction procedure to G_r,s and obtain a new Jordanian quantum group G_m,k. Furthermore, we provide a realisation of GL_h,h'(2) in terms of G_m,k. The contraction procedure is then extended to the coloured quantum group GL_r{\lambda,\mu}(2) to yield a new Jordanian quantum group GL_m{\lambda,\mu}(2). Both G_r,s and G_m,k are then generalised to their coloured versions which inturn provide similar realisations of GL_r{\lambda,\mu}(2) and GL_m{\lambda,\mu}(2).Comment: 22 pages LaTeX, to be published in J. Math. Phy

Molecular Subtype Classification Is a Determinant of Non-Sentinel Lymph Node Metastasis in Breast Cancer Patients with Positive Sentinel Lymph Nodes

Background: Previous studies suggested that the molecular subtypes were strongly associated with sentinel lymph node (SLN) status. The purpose of this study was to determine whether molecular subtype classification was associated with nonsentinel lymph nodes (NSLN) metastasis in patients with a positive SLN. Methodology and Principal Findings: Between January 2001 and March 2011, a total of 130 patients with a positive SLN were recruited. All these patients underwent a complete axillary lymph node dissection. The univariate and multivariate analyses of NSLN metastasis were performed. In univariate and multivariate analyses, large tumor size, macrometastasis and high tumor grade were all significant risk factors of NSLN metastasis in patients with a positive SLN. In univariate analysis, luminal B subgroup showed higher rate of NSLN metastasis than other subgroup (P = 0.027). When other variables were adjusted in multivariate analysis, the molecular subtype classification was a determinant of NSLN metastasis. Relative to triple negative subgroup, both luminal A (P = 0.047) and luminal B (P = 0.010) subgroups showed a higher risk of NSLN metastasis. Otherwise, HER2 over-expression subgroup did not have a higher risk than triple negative subgroup (P = 0.183). The area under the curve (AUC) value was 0.8095 for the Cambridge model. When molecular subtype classification was added to the Cambridge model, the AUC value was 0.8475. Conclusions: Except for other factors, molecular subtype classification was a determinant of NSLN metastasis in patient

Clinicopathologic Features Associated With Having Four or More Metastatic Axillary Nodes in Breast Cancer Patients With a Positive Sentinel Lymph Node

The survival benefit of a completion axillary lymph node dissection (ALND) in patients after removal of a metastatic sentinel lymph node (SLN) is uncertain and is under study in ongoing clinical trials. The completion ALND remains necessary, however, for the identification of cases with at least four metastatic lymph nodes, in which extended-field locoregional and/or postmastectomy radiation will be recommended. Our goal was evaluate clinicopathologic features that might serve as surrogates for determining which patients with a positive SLN are likely or unlikely to belong to this high-risk subset.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/41409/1/10434_2006_Article_9251.pd

Heat treatment effect on the structure and morphology of strontium monoacid orthophosphate thin films

International audienceHighly crystalline β-type strontium hydrogen phosphate (β-SrHPO4) thin films were prepared by a simple electrodeposition method. Their composition and morphology were investigated via X-ray diffraction (XRD) and a scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy system (EDX). It was found that both the structure and the morphology of the thin films were changed as a reason of a heat treatment at 600 °C

Update on neuroblastoma

Neuroblastoma is an embryonic cancer arising from neural crest stem cells. This cancer is the most common malignancy in infants and the most common extracranial solid tumor in children. The clinical course may be highly variable with the possibility of spontaneous regression in the youngest patients and increased risk of aggressive disease in older children. Clinical heterogeneity is a consequence of the diverse biologic characteristics that determine patient risk and survival. This review will focus on current progress in neuroblastoma staging, risk stratification, and treatment strategies based on advancing knowledge in tumor biology and genetic characterization. TYPE OF STUDY: Review article. LEVEL OF EVIDENCE: Level II