100 research outputs found
Utilizing the time delayed PPF controller to suppress vibrations of a nonlinear system containing real power exponents in damping and restoring forces
The time delayed Positive Position Feedback (PPF) controller is utilized to suppress the primary resonance of vibrations of an excited base oscillator by real power exponents of the restoring and damping forces. Multiple scales method is conducted to get the frequency response equations. The stability of the system is studied by using the Lyapunov first method. The influences of system parameters and time delay on the system response are investigated to avoid the jump phenomenon for better system performance. Time margin is deduced for most possible values of controller gain. Analytic results are verified by numerical integration of the original system equations
Controlling quarter car suspension system by proportional derivative and positive position feedback controllers with time delay
The active car suspension system is presented here to suppress the vibration of the car by applying proportional derivative (PD) and positive position feedback (PPF) controllers with time delay. The control signal output of the controller is applied electrically to the magneto-rheological (MR) damper or Electrical-rheological (ER) damper which is attached parallel to the passive components to improve the suppression of the vibration. The electrical control signal is produced by electronic circuits or programmable logic controller and the two-position sensor feedback signal which are connected to the controller. The approximate solutions of PD and PPF suspension systems are obtained by applying multiple time scales perturbation method. The effects of parameters variation of both the system and the controllers are investigated to achieve the best performance. Simulation results show good performance of the designed controllers
FORMULATION AND EVALUATION OF FLURBIPROFEN SUSTAINED RELEASE MATRIX TABLETS USING AN ALTERNATIVE TECHNIQUE AS POTENTIAL ECONOMIC APPROACH
Objective: Development of sustained released tablets of flurbiprofen (FP) using an alternative technique to the traditional method of wet granulation process aiming to lower labor cost of the granulation process and formulating tablets with better characteristics.
Methods: Eight matrix tablets formulae of FP were prepared by the alternative technique. The various characteristics of FP prepared tablets were investigated and comparatively evaluated by FP tablets prepared by the traditional method. The release data was analyzed according to various kinetic equations. The ulcerogenic effects of some FP tablets formulae were evaluated.
Results: FP tablets prepared by the alternative technique displayed the best physical characteristics. All FP prepared tablets displayed good sustained-release patterns. FP tablets prepared by the traditional method showed a progress decrease in drug dissolution by increasing matrix concentration and hence, more matrix agent or multiple granulations was needed which makes granulation process to be difficult and cost. While, FP tablets prepared by the alternative technique displayed dissolution profiles with minimal differences in-between reflecting the low labor cost of granulation process where good sustained patterns could be obtained by a minor of the matrix agent. Histologically, the ulcerogenic effects of FP on the rats were highly reduced by FP tablets prepared by the alternative technique rather than others. The release kinetics of different prepared FP tablets displayed a coupled release pattern between diffusion and dissolution.
Conclusion: This work proved the potential of the alternative technique as an effective economic approach for formulating FP sustained released tablets with better characteristics and low labor cost
A Risk Allocation Model for Construction Projects in Yemen
Construction projects in Yemen always experience high levels of risk due to their complex and dynamic environments. This, in turn, impacts projects in both time and cost. Obviously, risk allocation is usually poorly assigned to project parties; leading to terrible disputes among them. Moreover, there are no suitable risk allocation models that suit the nature of Yemen's construction industry. This work endeavors to propose and apply a Risk Allocation Model (RAM), based on a simple mechanism for allocating critical risks to the responsible party in the project. In addition, the RAM aims to compare among projects, which is more risky. The construction of RAM is based on Delphi method by the expert's judgment of construction projects. Fifty four risk factors, over ten groups, are identified and used in the model development. All factors are analyzed and weighted by deploying Weighted Risk Factor (WRF) which combines the effect of a risk factor probability and its effect on time and cost. The model results identified the most important risk factors to be allocated to owner, contractor or shared between them, as well as the suitable risk action for each factor. The model is applied on a real case study through two construction projects in Yemen to test the validation. A complete comparison between the two projects is presented and a decision is introduced for contractor based on projects time and cost overruns, WRF, and risk allocated to contractor. The results emphasized that the model is easy to understand and use by the parties involved in construction projects. Further, it is characterized by flexibility in the event of variables. The RAM outcomes thus help decision-makers to come to the appropriate decision during the trade-off among different projects. Keywords: Risk allocation, Delphi method, Construction projects, Decision-making, Yemen
A Combined Use of Rhizobacteria and Moringa Leaf Extract Mitigates the Adverse Effects of Drought Stress in Wheat (Triticum aestivum L.)
Less nutrient availability and drought stress are some serious concerns of agriculture. Both biotic and abiotic stress factors have the potential to limit crop productivity. However, several organic extracts obtained from moringa leaves may induce immunity in plants under nutritional and drought stress for increasing their survival. Additionally, some rhizobacterial strains have the ability to enhance root growth for better nutrient and water uptake in stress conditions. To cover the knowledge gap on the interactive effects of beneficial rhizobacteria and moringa leaf extracts (MLEs), this study was conducted. The aim of this experimental study was to investigate the effectiveness of sole and combined use of rhizobacteria and MLEs against nutritional and drought stress in wheat. Nitrogen-fixing bacteria Pseudomonas aeruginosa (Pa) (10(8) CFU ml(-1)) was inoculated to wheat plants with and without foliar-applied MLEs at two different concentrations (MLE 1 = 1:15 v/v and MLE 2 = 1:30 v/v) twice at 25 and 35 days after seed sowing (50 ml per plant) after the establishment of drought stress. Results revealed that Pa + MLE 2 significantly increased fresh weight (FW), dry weight (DW), lengths of roots and shoot and photosynthetic contents of wheat. A significant enhancement in total soluble sugars, total soluble proteins, calcium, potassium, phosphate, and nitrate contents validated the efficacious effect of Pa + MLE 2 over control-treated plants. Significant decrease in sodium, proline, glycine betaine, electrolyte leakage, malondialdehyde, hydrogen peroxide, superoxide dismutase (SOD), and peroxide (POD) concentrations in wheat cultivated under drought stress conditions also represents the imperative role of Pa + MLE 2 over control. In conclusion, Pa + MLE 2 can alleviate nutritional stress and drought effects in wheat. More research in this field is required to proclaim Pa + MLE 2 as the most effective amendment against drought stress in distinct agroecological zones, different soil types, and contrasting wheat cultivars worldwide.Peer reviewe
Integral effects of brassinosteroids and timber waste biochar enhances the drought tolerance capacity of wheat plant
Drought stress is among the major threats that affect negatively crop productivity in arid and semi-arid regions. Probably, application of some additives such as biochar and/or brassinosteroids could mitigate this stress; however, the mechanism beyond the interaction of these two applications is not well inspected. Accordingly, a greenhouse experiment was conducted on wheat (a strategic crop) grown under deficit irrigation levels (factor A) i.e., 35% of the water holding capacity (WHC) versus 75% of WHC for 35 days while considering the following additives, i.e., (1) biochar [BC, factor B, 0, 2%] and (2) the foliar application of 24-epibrassinolide [BR, factor C, 0 (control treatment, C), 1 (BR1) or 3 (BR2) mu mol)]. All treatments were replicated trice and the obtained results were statistically analyzed via the analyses of variance. Also, heat-map conceits between measured variables were calculated using the Python software. Key results indicate that drought stress led to significant reductions in all studied vegetative growth parameters (root and shoot biomasses) and photosynthetic pigments (chlorophyll a, b and total contents) while raised the levels of oxidative stress indicators. However, with the application of BC and/or BR, significance increases occurred in the growth attributes of wheat plants, its photosynthetic pigments, especially the combined additions. They also upraised the levels of enzymatic and non-enzymatic antioxidants while decreased stress indicators. Furthermore, they increased calcium (Ca), phosphorus (P) and potassium (K) content within plants. It can therefore be deduced that the integral application of BR and BC is essential to mitigate drought stress in plants.Peer reviewe
Exogenously applied ZnO nanoparticles induced salt tolerance in potentially high yielding modern wheat (Triticum aestivum L.) cultivars
Salinity stress is one of the potential threats that adversely affect the productivity of many cereal crops worldwide. Spraying plants with nano-Zn particles may lessen effectively such negative impacts on plants; yet its mode of action is still not well explored. This study was performed to evaluate the effects of spraying nano-Zn particles with varying concentrations (0, 20, 50 and 80 mg L-1) on two wheat cultivars irrigated with saline water (EC = 6.3 dS m-1) versus a non-saline one. The key results revealed that root and shoot weights decreased significantly under salinity stress conditions, while improved considerably with nano-Zn-particles foliar application up to 50 mg nanoZn L-1; thereafter significant reductions occurred. Also, shoot and root lengths as well as plant leaf area index improved considerably owing to this foliar application. Clearly, roots and shoots weights of wheat plants sprayed with nano-Zn particles under salinity stress conditions exhibited higher values than the corresponding ones that was grown under non-saline conditions without nano-Zn-particles applications. Unexpectedly, this foliar spray led to significant reductions in plant pigments and also in enzymatic and non-enzymatic antioxidants in plants. Yet, this foliar spray enhanced formation of total soluble sugars and proline, and raised significantly Ca contents in wheat roots and shoots, and to some extent K contents. In conclusion, the foliar application of nano-Zn particles increased plant growth under salty stress conditions via two parallel processes, i.e., stimulating formation of osmolytes and stimulating nutrient uptake which may, in turn, increase plant metabolism. (c) 2022 The Author(s). Published by Elsevier B.V. This is an open access article under the CCPeer reviewe
Vitrification of mouse embryo-derived ICM cells: a tool for preserving embryonic stem cell potential?
Associative effects of activated carbon biochar and arbuscular mycorrhizal fungi on wheat for reducing nickel food chain bioavailability
Heavy metal stress and less nutrient availability are some of the major concerns in agriculture. Both abiotic stresses have potential to decrease the crops productivity. On the other hand, organic fertilizers i.e., activated carbon biochar (ACB) and arbuscular mycorrhizal fungi (AMF) increase nutritional and heavy metal like Nickel (Ni) stress tolerance and provide immunity to plants for their survival in unfavorable environments. Previous studies have only looked at single applications of either ACB or AMF thus far. There is limited evidence of their synergistic effects, especially in plants growing in soil contaminated with nickel (Ni). To cover the knowledge gap of combined use of AMF inoculation (Glomus intraradices) and/or wheat straw biochar amendments on wheat growth, antioxidant activities and osmolytes concentration, present study is conducted. The use of either the AMF inoculant or the ACB alone resulted in improved wheat growth and decreased Ni uptake. Furthermore, sole AMF or ACB also reduced Ni stress effectively, allowing wheat to grow faster and reducing soil Ni transfer into plant tissue. In comparison to a control, adding ACB with AMF inoculant considerably increased fungal populations. The most significant increase in wheat growth and decrease in tissue Ni contents came from amending soil with AMF inoculant and biochar. Inducing soil alkalinization and causing Ni immobilization, as well as decreasing Ni phyto-availability, the combination treatment had a synergistic impact. These findings imply that AMF inoculation in ACB treatment could be used not only for wheat production but also for Ni-contaminated soil phyto-stabilization. (C) 2022 The Author(s). Published by Elsevier B.V.Peer reviewe
Association of IL28B SNP With Progression of Egyptian HCV Genotype 4 Patients to End Stage Liver Disease
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