2,027 research outputs found
Fuzzy Maximum Satisfiability
In this paper, we extend the Maximum Satisfiability (MaxSAT) problem to
{\L}ukasiewicz logic. The MaxSAT problem for a set of formulae {\Phi} is the
problem of finding an assignment to the variables in {\Phi} that satisfies the
maximum number of formulae. Three possible solutions (encodings) are proposed
to the new problem: (1) Disjunctive Linear Relations (DLRs), (2) Mixed Integer
Linear Programming (MILP) and (3) Weighted Constraint Satisfaction Problem
(WCSP). Like its Boolean counterpart, the extended fuzzy MaxSAT will have
numerous applications in optimization problems that involve vagueness.Comment: 10 page
The clinical characteristics, presentation, and treatment outcomes of prolactinomas at Groote Schuur Hospital
Background: Prolactin-secreting tumours( prolactinomas) are the commonest type of pituitary tumour, accounting for approximately 30 to 40 %% of all pituitary adenomas. Although there is ample epidemiologic and clinic data from Industrialised countries there remains sparse data from Africa. Specifically, the clinical presentation, and hormonal deficiencies and treatment outcomes in the South Africa have not been described. Methods: A retrospective study of all patients with a diagnosis of prolactinoma attending the Endocrine and Pituitary Clinics at Groote Schuur Hospital over a 12-month period, between March 2019-March 2020. Patients folders were reviewed to retrieve the following information: demographic data, clinical presentation, clinical signs, prolactinoma phenotype, hormonal deficiencies, treatment modalities and clinical outcomes. Results: Over a 12-month period 52 patients were included in this study, females 73% (n=38), mean age of all participants was 46.1 ± 14.6 years. A macroprolactinoma was present in 67.3% (n=35) of patients and 32.7% (n=17) of patients had a microprolactinoma. In the macroprolactinoma group: the common presenting symptoms were headache 88.6% (n=33), altered vision 40% (n=14) and , in females, amenorrhoea 63.6% (n=14) but a cranial nerve palsy 17.1% (n=6) and apoplexy 5.7% (n=2) were uncommon. . In the microprolactinoma group the common presenting symptoms included amenorrhoea 75% (n=12), galactorrhoea 70.6% (n=12), headache 64.7% (n=11). On presentation the majority of patients with a macroadenoma had at least one hormonal abnormality with hypogonadism 73.1% (n=19) being most common, followed by hypothyroidism 53.8% (n=14) and hypoadrenalism 30% (n=8). Over 50% of patients with a giant adenoma had panhypopituitarism with hypogonadism in 100%, hypothyroidism in 77.8% (n=7) and hypoadrenalism in 66.7% (n=6). Hormonal deficiencies in the microadenoma group on presentation included hypogonadism 64.7% (n=11), hypothyroidism 35.3 (n=6) and one patient had hypoadrenalism. All patients received medical treatment, however, in the macroadenoma group 4 patients required surgical debulking of the tumour, 3 patients required a ventriculo-peritoneal (VP) shunt for hydrocephalus and 2 patients required radiation. After a median follow-up of 46.5 months, the median prolactin level decreased from 322.5 ug/l (94.0-4282.0) at presentation to 17.5 ug/l (8.6-82.5) at follow-up. In parallel there was a reduction of 12.2 ±9.7 mm in tumour size after a mean of 59.8 ±53.3 months. There was resolution of hypogonadism in 56.4% (n=22), of hypothyroidism in 2.7% (n=2) and hypoadrenalism only resolved in 1 patient. Conclusions: Most patients with a prolactinoma are symptomatic and have at least one hormone deficiency on presentation. With medical management most patients experienced a reduction in prolactin levels and tumour size. . This was associated with the resolution of hypogonadism in the majority, however, hypothyroidism and hypoadrenalism are unlikely to resolve despite a reduction in tumour size
Analysis of IVAT laboratory grounding system using CDEGS software
Practical tests on grounding systems has proved very costly and pose hazards on operating personnel. Therefore, numerical methods using computers provide the m ost appropriate tool to assess the earthing systems. The research has been conducted with the utilization o f CDEGS software as a tool to simulate all necessary phenomena on the built CDEGS model o f the grounding system in IV A T’s laboratory. In particular, the ground potential rise, touch voltages, and step voltages plots are the main outputs generated. Six lightning scenarious catergorized into low, medium and hight levels are applied on the proposed grounding system to assess for the IVAT’s earthing structure safety. The IEEE 80-2000 standard is used to calculate the maximum allowable limits for surface potentials and employed as set point. Obtained results were compared to the safety lim it of the standard and proved safe only for the low level when no protective layer is in use. However, the system was completely safe and m et the standard’s limits for low, medium and high levels of lightning strikes when a protective layer is in place
Heavy Metals Uptake By Chilli Plants (Capsicum Annuum L.) Planted In Rice Husk Char And Coco Peat Media
The current study investigated the uptake of Cadmium (Cd2+) and Lead (Pb2+) by chilli plant and their effect on the plant growth and fruit quality.
Kajian ini mengkaji pengambilan Kadmium (Cd2+) dan Plumbum (Pb2+) oleh pokok cili merah dan kesannya terhadap pertumbuhan tanaman dan kualiti buah-buahan
Design and Simulation of a Low Frequency Electrostatic Comb-drive Energy Harvester Using 0.35μm CMOS Technology
This project is to design, model and simulate an electrostatic comb-drive energy harvester. The device harvests the vibration energy from outside source and converts it into electric energy to supply wireless node sensors. Simulation is conducted using the CoventorWare software to simulate and optimize the device. CoventorWare simulation result has obtained a resonant frequency of 5 KHz
Unveiling Innovations in Grasslands Productivity and Sustainability
Funding: This work is funded by the Super g project (funded under EU Horizon 2020 programme: project number 774124). Acknowledgments: I acknowledge the efforts of the authors, reviewers, and editors who significantly contributed to the success of this Special IssuePeer reviewedPublisher PD
The Impact of Government Policies on Foreign Direct Investment in Developing Countries: the Case of Sudan
Currently, policies implemented by governments in developing countries are dominated by the view that Foreign Direct Investment (FDI) is necessary for development and that, without FDI, there would be no growth. They also believe that FDI brings efficient management of resources, new technology, a culture of competition, and access to global markets. FDI is considered the best source of development finance on the grounds, among others, that it is self-liquidating. Obviously, Sudan is not an exception, with policies of economic liberalisation, policies of economic restructuring, attention to the infrastructure, privatisation, and establishment of the capital market, and other measures to attract FDI.
The aim of this research is to explore the impact of policies followed by the host country on the amount of inward FDI and the impact of FDI on the economic development of the host country. It is important to focus on the theoretical foundation of the FDI phenomenon and its relevance in explaining FDI determinants.
In conducting this research, a combination of qualitative and quantitative methods have been employed. A case study approach has been adopted to investigate the impact of the measures taken by the government of Sudan to encourage FDI. As well as investigating the impact at the macroeconomic level, the study focuses on the three sectors most affected by FDI: oil, real estate and telecommunications.
Oil production and exports are of vital importance for Sudan’s economy, and hence the government has focused much of its effort on this sector, which is dominated by Chinese companies. Many of the issues faced were similar to those experienced elsewhere in Africa where China is the source of FDI. The inflows to the real estate sector were mainly from the Gulf, with developers seeking to build residential accommodation and commercial property which would appeal to Sudanese expatriates returning from work there. Telecommunications, in particular mobile services, have brought about a social revolution in Sudan, as well as elsewhere in Africa. The government’s aim was to open the market up, with competition making phone tariffs more affordable. Overall, government policies to encourage FDI have been successful but it is evident that different policies are needed for each sector
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