Searching for Gravitational Waves from Binary Inspirals with LIGO

We describe the current status of the search for gravitational waves from inspiralling compact binary systems in LIGO data. We review the result from the first scientific run of LIGO (S1). We present the goals of the search of data taken in the second scientific run (S2) and describe the differences between the methods used in S1 and S2.Comment: 9 pages, 2 figures. Published in proceedings of the 8th Gravitational Wave Data Analysis Workshop, Milwaukee, WI, USA, 17-20 December 200

Negative Energy in String Theory and Cosmic Censorship Violation

We find asymptotically anti de Sitter solutions in N=8 supergravity which have negative total energy. This is possible since the boundary conditions required for the positive energy theorem are stronger than those required for finite mass (and allowed by string theory). But stability of the anti de Sitter vacuum is still ensured by the positivity of a modified energy, which includes an extra surface term. Some of the negative energy solutions describe classical evolution of nonsingular initial data to naked singularities. Since there is an open set of such solutions, cosmic censorship is violated generically in supergravity. Using the dual field theory description, we argue that these naked singularities will be resolved in the full string theory.Comment: 23 pages, 2 figures, v2: argument for forming naked singularities clarified, references adde

Cosmic Strings and Superstrings

Cosmic strings are predicted by many field-theory models, and may have been formed at a symmetry-breaking transition early in the history of the universe, such as that associated with grand unification. They could have important cosmological effects. Scenarios suggested by fundamental string theory or M-theory, in particular the popular idea of brane inflation, also strongly suggest the appearance of similar structures. Here we review the reasons for postulating the existence of cosmic strings or superstrings, the various possible ways in which they might be detected observationally, and the special features that might discriminate between ordinary cosmic strings and superstrings.Comment: Minor errors corrected and some references added, 34 pages, 6 figure

Bounds on Universal Extra Dimensions

We show that the bound from the electroweak data on the size of extra dimensions accessible to all the standard model fields is rather loose. These "universal" extra dimensions could have a compactification scale as low as 300 GeV for one extra dimension. This is because the Kaluza-Klein number is conserved and thus the contributions to the electroweak observables arise only from loops. The main constraint comes from weak-isospin violation effects. We also compute the contributions to the S parameter and the $Zb\bar{b}$ vertex. The direct bound on the compactification scale is set by CDF and D0 in the few hundred GeV range, and the Run II of the Tevatron will either discover extra dimensions or else it could significantly raise the bound on the compactification scale. In the case of two universal extra dimensions, the current lower bound on the compactification scale depends logarithmically on the ultra-violet cutoff of the higher dimensional theory, but can be estimated to lie between 400 and 800 GeV. With three or more extra dimensions, the cutoff dependence may be too strong to allow an estimate.Comment: 22 pages, Latex, 1 eps figure. Published version; minor correction in the Kaluza-Klein decompositio

Semi-Inclusive Lambda and Kshort Production in p-Au Collisions at 17.5 GeV/c

The first detailed measurements of the centrality dependence of strangeness production in p-A collisions are presented. Lambda and Kshort dn/dy distributions from 17.5 GeV/c p-Au collisions are shown as a function of "grey" track multiplicity and the estimated number of collisions, nu, made by the proton. The nu dependence of the Lambda yield deviates from a scaling of p-p data by the number of participants, increasing faster than this scaling for nu<=5 and saturating for larger nu. A slower growth in Kshort multiplicity with nu is observed, consistent with a weaker nu dependence of K-Kbar production than Y-K production.Comment: 5 pages, 3 figures, formatted with RevTex, current version has enlarged figure catpion

B Production Asymmetries in Perturbative QCD

This paper explores a new mechanism for B production in which a b quark combines with a light parton from the hard-scattering process before hadronizing into the B hadron. This recombination mechanism can be calculated within perturbative QCD up to a few nonperturbative constants. Though suppressed at large transverse momentum by a factor Lambda_QCD m_b/p_t^2 relative to b quark fragmentation production, it can be important at large rapidities. A signature for this heavy-quark recombination mechanism in proton-antiproton colliders is the presence of rapidity asymmetries in B cross sections. Given reasonable assumptions about the size of nonperturbative parameters entering the calculation, we find that the asymmetries are only significant for rapidities larger than those currently probed by collider experiments.Comment: 17 pages, LaTeX, 4 ps figures, tightenlines, sections added, final version accepted for publication in Phys. Rev.

Don't Stop Thinking About Leptoquarks: Constructing New Models

We discuss the general framework for the construction of new models containing a single, fermion number zero scalar leptoquark of mass $\simeq 200-220$ GeV which can both satisfy the D0/CDF search constraints as well as low energy data, and can lead to both neutral and charged current-like final states at HERA. The class of models of this kind necessarily contain new vector-like fermions with masses at the TeV scale which mix with those of the Standard Model after symmetry breaking. In this paper we classify all models of this type and examine their phenomenological implications as well as their potential embedding into SUSY and non-SUSY GUT scenarios. The general coupling parameter space allowed by low energy as well as collider data for these models is described and requires no fine-tuning of the parameters.Comment: Modified text, added table, and updated reference

Cardiorespiratory fitness is associated with hard and light intensity physical activity but not time spent sedentary in 10–14 year old schoolchildren: the HAPPY study

Sedentary behaviour is a major risk factor for developing chronic diseases and is associated with low cardiorespiratory fitness in adults. It remains unclear how sedentary behaviour and different physical activity subcomponents are related to cardiorespiratory fitness in children. The purpose of this study was to assess how sedentary behaviour and different physical activity subcomponents are associated with 10–14 year-old schoolchildren's cardiorespiratory fitness

Functional Genomic and Proteomic Analysis Reveals Disruption of Myelin-Related Genes and Translation in a Mouse Model of Early Life Neglect

Early life neglect is an important public health problem which can lead to lasting psychological dysfunction. Good animal models are necessary to understand the mechanisms responsible for the behavioral and anatomical pathology that results. We recently described a novel model of early life neglect, maternal separation with early weaning (MSEW), that produces behavioral changes in the mouse that persist into adulthood. To begin to understand the mechanism by which MSEW leads to these changes we applied cDNA microarray, next-generation RNA-sequencing (RNA-seq), label-free proteomics, multiple reaction monitoring (MRM) proteomics, and methylation analysis to tissue samples obtained from medial prefrontal cortex to determine the molecular changes induced by MSEW that persist into adulthood. The results show that MSEW leads to dysregulation of markers of mature oligodendrocytes and genes involved in protein translation and other categories, an apparent downward biasing of translation, and methylation changes in the promoter regions of selected dysregulated genes. These findings are likely to prove useful in understanding the mechanism by which early life neglect affects brain structure, cognition, and behavior