Development of a technology for producing a gel composition for the treat-ment of an allergy complicated by fungal infection

The results of the development of the technology of the combined external drug for the treatment of allergies compli-cated by fungal infection are given. The rheological properties of the gel composition were studied in comparison with the similar preparation Fenistil gel, it was shown that the dynamic viscosity of the drug is 4.1 Pa·s, the active components (diphenylhydramine, fluconazole, Timoptin) do not destroy the structure of the gel base. A technological and instrumental scheme for the production of the drug has been developed

Polymer-Based Hybrid Nanoarchitectures for Cancer Therapy Applications

Globally, cancer is affecting societies and is becoming an important cause of death. Chemotherapy can be highly effective, but it is associated with certain problems, such as undesired targeting and multidrug resistance. The other advanced therapies, such as gene therapy and peptide therapy, do not prove to be effective without a proper delivery medium. Polymer-based hybrid nanoarchitectures have enormous potential in drug delivery. The polymers used in these nanohybrids (NHs) provide them with their distinct properties and also enable the controlled release of the drugs. This review features the recent use of polymers in the preparation of different nanohybrids for cancer therapy published since 2015 in some reputed journals. The polymeric nanohybrids provide an advantage in drug delivery with the controlled and targeted delivery of a payload and the irradiation of cancer by chemotherapeutical and photodynamic therapy