ChemInform Abstract: Zinc Chloride‐Catalyzed Expeditious Route to Nitriles

A simple, solvent-free, and efficient method to get nitriles by microwave-assisted reaction of different aromatic aldehydes with hydroxylamine in the presence of ZnCl2 is described

ChemInform Abstract: An Efficient and Solvent‐Free One‐Pot Synthesis of Nitriles from Aldehydes

The process is green, efficient and extremely inexpensive

p-TSA catalysed efficient synthesis of 1,2,4,5-tetraaryl-imidazoles

Abstractp-TSA catalysed simple and efficient synthesis of 1,2,4,5-tetraaryl-imidazoles via a four component condensation of benzoin, aniline, ammonium acetate and araldehydes in ethanol under reflux condition is reported. The yields are high, procedure is mild and less time consuming

Molecular Iodine Catalysed One Pot Synthesis of Spirooxindoles by Tandem Knoevenagel Cyclisation

Spirooxindoles are heterocycles found in various natural and synthetic products with potent bio-, physio-, and pharmaceutical activities. Heterocyclic fused phthalazines possess   antimicrobial, antifungal, anticancer, anti- inflammatory, and cardiotonic activities. Hence, an efficient multi-component method has been developed for the synthesis of pyrazolophthalazinyl spirooxindoles through tandem Knoevenagel cyclisation from isatin, malononitrile and various phthalhydrazides in presence of readily available molecular iodine as a catalyst in ethanol solvent under ultrasonic condition to afford the products in very good yield within 15 mins. The method is simple, efficient, uses readily available commercial starting materials and gives good yield of product in short reaction time

Amberlite IR-120H: An improved reusable solid phase catalyst for the synthesis of nitriles under solvent free microwave irradiation

An efficient green protocol has been developed for the conversion of a range of aldehydes to the corresponding nitriles using a solid-phase reusable catalyst combined with microwave irradiation. The highlighting features of this method are short reaction time, environmentally compatible, reusability of the catalyst and good product yield

Solvent-free synthesis of 2H-indazolo[2,1-b] phthalazine-triones promoted by cavitational phenomenon using iodine as catalyst

An environmentally benign, simple and efficient protocol for the synthesis of 2H-indazolo[2,1-b] phthalazine-triones by condensation of phthalhydrazide, aromatic aldehydes and dimedone under solvent-free ultrasound assisted conditions employing a safe, readily available iodine as catalyst has been described. This process is a valuable addition as it devoids the use of any solvent and takes place in short duration of time giving good yield of the products