37 research outputs found

    Preparation and characterization of tunable oil-encapsulated alginate microfibers

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    © 2017 Elsevier LtdA single-step microfluidic approach was developed which allowed a wide range of oil-loaded calcium-alginate microfibers to be fabricated at the same compositions but with different morphologies. A framework for characterization of wavy fibers was developed which linked the fiber morphology and tensile strength to the encapsulation type and geometry. The geometry of oil encapsulates as well as the fibers surface morphology were conveniently tuned via the gelation reaction dynamics and phase flow rates. A 2D mathematical reconstruction of the fiber's surface revealed that fibers having spherical and ellipsoid encapsulates enjoyed the highest surface roughness. Tubular fibers endured the highest tensile force before failure, compared to fibers with other encapsulate geometries at a fixed alginate phase ratio (ϕalg). Fibers with increased ϕalg withstood a higher tensile force. However, the strength of fibers reduced if the increase in ϕalg altered the encapsulate geometry from tubular to discrete oil segments. Tubular fibers also underwent maximum elastic and plastic deformation prior to failure, among all fibers

    Cognitive reactivity: cultural adaptation and psychometric testing of the Persian version of the Leiden Index of Depression Sensitivity Revised (LEIDS-R) in an Iranian sample

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    Cognitive reactivity (CR) to the experimental induction of sad mood has been found to predict relapse in recovered depressed patients. The Leiden Index of Depression Sensitivity Revised (LEIDS-R) is a self-report measure of CR. The aim of the present study was to establish the validity and reliability of the Persian version of the LEIDS-R. The participants were recovered depressed and non-depressed Iranian individuals (n = 833). The analyses included content validation, factor analysis, construct validity, and reliability testing. Preliminary construct validation analysis confirmed that factor analysis was appropriate for the Persian version of the LEIDS-R. Factor analysis displayed similar factor loadings to the original English version. The total internal consistency of the translated version, which was assessed using Cronbach’s alpha coefficient, was equal to 0.90. The test-retest reliability of the total score was equal to that of the test-retest conducted after a two-week interval at 0.94. Content validity, face validity, and construct validity, as well as reliability analysis were all found to be satisfactory for the Persian version of the LEIDS-R. The Persian version of the LEIDS-R appears to be valid and reliable for use in future studies, and has properties comparable to the original version and to that obtained in previous studies
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