Effect of luteinized unruptured follicle cycles on clinical outcomes of frozen thawed embryo transfer in Chinese women

Objective To determine the effect of luteinized unruptured follicle (LUF) cycles on frozen thawed embryo transfer (FET). Design A retrospective analysis comparing the clinical outcomes after FET among 144 cases of luteinized unruptured follicle (LUF) cycles and 866 cases of ovulation cycles. Setting Reproductive medical center, Beijing China. Patient(s) Chinese infertile women who underwent FET. Intervention(s) None. Main outcome measure(s) Clinical pregnancy rate (PR), implantation rate. Result(s) The implantation rate, clinical pregnancy rate, on-going pregnancy rate and live birth rate in LUF group were 12.76% (49/384), 27.78% (40/144), 24.31% (35/144) and 19.44% (28/144), respectively, and in ovulation group, 14.74% (332/2251), 31.29% (271/866), 28.29% (245/866) and 22.23% (193/866), respectively (p > 0.05). Conclusion(s) LUF does not affect the clinical outcomes of FET. Patients of LUF should be included in FET treatment.Genetics & HeredityObstetrics & GynecologyReproductive BiologySCI(E)PubMed5ARTICLE6229-2332

Leiomyomatosis peritonealis disseminata in association with Currarino syndrome?

<p>Abstract</p> <p>Background</p> <p>Leiomyomatosis peritonealis disseminata (LPD) is a rare disease in which multiple smooth muscle or smooth muscle-like nodules develop subperitoneally in any part of the abdominal cavity. No reports of multiple congenital malformations associated with LPD have been found in the English literature.</p> <p>Case presentation</p> <p>A 27 year-old patient referred to our gynaecology unit for pelvic pain, amenorrhoea, stress incontinence, chronic constipation and recurrent intestinal and urinary infections. Multiple congenital malformations had previously been diagnosed. Most of these had required surgical treatment in her early life: anorectal malformation with rectovestibular fistula, ectopic right ureteral orifice, megadolichoureter and hemisacrum.</p> <p>An ultrasound scan and computed tomography performed in our department showed an irregular, polylobate, complex 20 cm mass originating from the right pelvis that reached the right hypochondrium and the epigastrium. The patient underwent laparotomy. The three largest abdominal-pelvic masses and multiple independent nodules within the peritoneum were progressively removed. The histological diagnosis was of LPD.</p> <p>Conclusion</p> <p>The case we report is distinctive in that a rare acquired disease, LPD, coexists with multiple congenital malformations recalling a particular subgroup of caudal regression syndrome: the Currarino syndrome.</p