12,874 research outputs found

    Few-Shot Single-View 3-D Object Reconstruction with Compositional Priors

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    The impressive performance of deep convolutional neural networks in single-view 3D reconstruction suggests that these models perform non-trivial reasoning about the 3D structure of the output space. However, recent work has challenged this belief, showing that complex encoder-decoder architectures perform similarly to nearest-neighbor baselines or simple linear decoder models that exploit large amounts of per category data in standard benchmarks. On the other hand settings where 3D shape must be inferred for new categories with few examples are more natural and require models that generalize about shapes. In this work we demonstrate experimentally that naive baselines do not apply when the goal is to learn to reconstruct novel objects using very few examples, and that in a \emph{few-shot} learning setting, the network must learn concepts that can be applied to new categories, avoiding rote memorization. To address deficiencies in existing approaches to this problem, we propose three approaches that efficiently integrate a class prior into a 3D reconstruction model, allowing to account for intra-class variability and imposing an implicit compositional structure that the model should learn. Experiments on the popular ShapeNet database demonstrate that our method significantly outperform existing baselines on this task in the few-shot setting

    Unusual Thermodynamics on the Fuzzy 2-Sphere

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    Higher spin Dirac operators on both the continuum sphere(S2S^2) and its fuzzy analog(SF2S^2_F) come paired with anticommuting chirality operators. A consequence of this is seen in the fermion-like spectrum of these operators which is especially true even for the case of integer-spin Dirac operators. Motivated by this feature of the spectrum of a spin 1 Dirac operator on SF2S_F^2, we assume the spin 1 particles obey Fermi-Dirac statistics. This choice is inspite of the lack of a well defined spin-statistics relation on a compact surface such as S2S^2. The specific heats are computed in the cases of the spin 12\frac{1}{2} and spin 1 Dirac operators. Remarkably the specific heat for a system of spin 12\frac{1}{2} particles is more than that of the spin 1 case, though the number of degrees of freedom is more in the case of spin 1 particles. The reason for this is inferred through a study of the spectrums of the Dirac operators in both the cases. The zero modes of the spin 1 Dirac operator is studied as a function of the cut-off angular momentum LL and is found to follow a simple power law. This number is such that the number of states with positive energy for the spin 1 and spin 12\frac{1}{2} system become comparable. Remarks are made about the spectrums of higher spin Dirac operators as well through a study of their zero-modes and the variation of their spectrum with degeneracy. The mean energy as a function of temperature is studied in both the spin 12\frac{1}{2} and spin 1 cases. They are found to deviate from the standard ideal gas law in 2+1 dimensions.Comment: 19 pages, 7 figures. The paper has been significantly modified. Main results are unchange

    Effects of stitching on delamination of satin weave carbon-epoxy laminates under mode I, mode II and mixed-mode I/II loadings

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    The objective of the present study is to characterize the effect of modified chain stitching on the delamination growth under mixed-mode I/II loading conditions. Delamination toughness under mode I is experimentally determined, for unstitched and stitched laminates, by using untabbed and tabbed double cantilever beam (TDCB) tests. The effect of the reinforcing tabs on mode I toughness is investigated. Stitching improves the energy release rate (ERR) up to 4 times in mode I. Mode II delamination toughness is evaluated in end-notched flexure (ENF) tests. Different geometries of stitched specimens are tested. Crack propagation occurs without any failure of stitching yarns. The final crack length attains the mid-span or it stops before and the specimen breaks in bending. The ERR is initially low and gradually increases with crack length to very high values. The mixedmode delamination behaviour is investigated using a mixed-mode bending (MMB) test. For unstitched specimens, a simple mixed-mode criterion is identified. For stitched specimens, stitching yarns do not break during 25% of mode I ratio tests and the ERR increase is relatively small compared to unstitched values. For 70% and 50% of mode I ratios, failures of yarns are observed during crack propagation and tests are able to capture correctly the effect of the stitching: it clearly improves the ERR for these two mixed modes, as much as threefold

    The electric field alignment of short carbon fibres to enhance the toughness of epoxy composites

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    An investigation is presented on increasing the fracture toughness of epoxy/short carbon fibre (SCF) composites by alignment of SCFs using an externally applied alternating current (AC) electric field. Firstly, the effects of SCF length, SCF content and AC electric field strength on the rotation of the SCFs suspended in liquid (i.e. uncured) epoxy resin are investigated. Secondly, it is shown the mode I fracture toughness of the cured epoxy composites increases with the weight fraction of SCFs up to a limiting value (5 wt%). Thirdly, the toughening effect is greater when the SCFs are aligned in the composite normal to the direction of crack growth. The SCFs increases the fracture toughness by inducing multiple intrinsic and extrinsic toughening mechanisms, which are identified. Based on the identified toughening mechanisms, an analytical model is proposed to predict the enhancement to the fracture toughness due to AC electric field alignment of the SCFs

    PGI13 LOWER DISEASE ACTIVITY AND CLINICAL REMISSION ARE ASSOCIATED WITH REDUCED HOSPITALIZATION RISK IN CROHN'S DISEASE

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    Network Analysis of Breast Cancer Progression and Reversal Using a Tree-Evolving Network Algorithm

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    The HMT3522 progression series of human breast cells have been used to discover how tissue architecture, microenvironment and signaling molecules affect breast cell growth and behaviors. However, much remains to be elucidated about malignant and phenotypic reversion behaviors of the HMT3522-T4-2 cells of this series. We employed a "pan-cell-state" strategy, and analyzed jointly microarray profiles obtained from different state-specific cell populations from this progression and reversion model of the breast cells using a tree-lineage multi-network inference algorithm, Treegl. We found that different breast cell states contain distinct gene networks. The network specific to non-malignant HMT3522-S1 cells is dominated by genes involved in normal processes, whereas the T4-2-specific network is enriched with cancer-related genes. The networks specific to various conditions of the reverted T4-2 cells are enriched with pathways suggestive of compensatory effects, consistent with clinical data showing patient resistance to anticancer drugs. We validated the findings using an external dataset, and showed that aberrant expression values of certain hubs in the identified networks are associated with poor clinical outcomes. Thus, analysis of various reversion conditions (including non-reverted) of HMT3522 cells using Treegl can be a good model system to study drug effects on breast cancer. © 2014 Parikh et al

    Penetration and intracellular uptake of poly(glycerol-adipate)nanoparticles into 3-dimensional brain tumour cell culture models

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    Nanoparticle (NP) drug delivery systems may potentially enhance the efficacy of therapeutic agents. It is difficult to characterise many important properties of NPs in vivo and therefore attempts have been made to use realistic in vitro multicellular spheroids instead. In this paper we have evaluated poly(glycerol-adipate) (PGA) NPs as a potential drug carrier for local brain cancer therapy. Various 3-dimensional (3-D) cell culture models have been used to investigate the delivery properties of PGA NPs. Tumour cells in 3-D culture showed a much higher level of endocytic uptake of NPs than a mixed normal neonatal brain cell population. Differences in endocytic uptake of NPs in 2-D and 3-D models strongly suggest that it is very important to use in vitro 3-D cell culture models for evaluating this parameter. Tumour penetration of NPs is another important parameter which could be studied in 3-D cell models. The penetration of PGA NPs through 3-D cell culture varied between models, which will therefore require further study to develop useful and realistic in vitro models. Further use of 3-D cell culture models will be of benefit in the future development of new drug delivery systems, particularly for brain cancers which are more difficult to study in vivo
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